Abstract
Portable isolation units (PIUs) represent a critical component in the management of chemical, biological, radiological and nuclear (CBRN) threats, as well as for addressing broader medical needs during infectious disease outbreaks. These units are designed to offer a controlled environment that can be easily deployed to isolate individuals either suspected of carrying infectious agents or contaminated with hazardous materials. The functionality of PIUs is enhanced by their ability to maintain specific atmospheric conditions, such as positive or negative pressure, to prevent the spread of contaminants. In the context of CBRN threats, PIUs provide a safe space for decontamination and initial medical treatment, reducing the risk of broader environmental contamination and exposure. Similarly, during pandemics or outbreaks of highly infectious diseases, PIUs are indispensable for containing pathogens and protecting both healthcare personnel and the public. This study outlines the design and testing of the BIOEVAC portable isolation unit, which can operate with both positive and negative pressure for transporting contaminated individuals. Originally developed as a technological demonstrator during the COVID-19 pandemic for emergency use, its capabilities have been enhanced and it has now been transferred to the industry for mass production.