Correlation of duration of β-1,3/1,6-glucan administration with the effectiveness of immune stimulation in juvenile vimba bream (Vimba vimba)
References
- Amphan S., Unajak S., Printrakoon C., Areechon N.: Feeding-regimen of β-glucan to enhance innate immunity and disease resistance of Nile tilapia, Oreochromis niloticus Linn., against Aeromonas hydrophila and Flavobacterium columnare. Fish Shellfish Immunol 2019, 87, 120–128, doi: 10.1016/j.fsi.2018.12.062.
- Aramli M.S., Kamangar B., Nazari R.M.: Effects of dietary β-glucan on the growth and innate immune response of juvenile Persian sturgeon, Acipenser persicus. Fish Shellfish Immunol 2015, 47, 606–610, doi: 10.1016/j.fsi.2015.10.004.
- Bagni M., Romano N., Finoia M.G., Abelli L., Scapigliati G., Tiscar P.G., Sarti M., Marino G.: Short-and long-term effects of a dietary yeast β-glucan (Macrogard) and alginic acid (Ergosan) preparation on immune response in sea bass (Dicentrarchus labrax). Fish Shellfish Immunol 2005, 18, 311–325, doi: 10.1016/j.fsi.2004.08.003.
- Ching J.J., Shuib A.S., Majid N.A., Taufek N.M.: Immunomodulatory activity of β-glucans in fish: Relationship between β-glucan administration parameters and immune response induced. Aquacult Res 2021, 52, 1824–1845, doi: 10.1111/are.15086.
- Gopalakannan A., Arul V.: Enhancement of the innate immune system and disease-resistant activity in Cyprinus carpio by oral administration of β-glucan and whole cell yeast. Aquacult Res 2010, 41, 884–892, doi: 10.1111/j.1365-2109.2009.02368.x.
- Huu H.D., Sang H.M., Thuy N.T.T.: Dietary β-glucan improved growth performance, Vibrio counts, haematological parameters and stress resistance of pompano fish, Trachinotus ovatus Linnaeus, 1758. Fish Shellfish Immunol 2016, 54, 402–410, doi: 10.1016/j.fsi.2016.03.161.
- Ji L., Sun G., Li J., Wang Y., Du Y., Li X., Liu Y.: Effect of-dietary β-glucan on growth, survival and regulation of immune processes in rainbow trout (Oncorhynchus mykiss) infected by Aeromonas salmonicida. Fish Shellfish Immunol 2017, 64, 56–67, doi: 10.1016/j.fsi.2017.03.015.
- Kazuń B., Kazuń K., Małaczewska J., Kamiński R., Adamek-Urbańska D., Sikorska J., Wolnicki J., Szudrowicz H.: Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba (Vimba vimba). J Vet Res 2023, 67, 233–241, doi: 10.2478/jvetres-2023-0033.
- Kazuń B., Małaczewska J., Kazuń K., Kamiński R., Adamek-Urbańska D., Żylińska J.: Dietary administration of β-1,3/1,6-glucan and Lactobacillus plantarum improves innate immune response and increases the number of intestine immune cells in roach (Rutilus rutilus). BMC Vet Res 2020, 16, 216, doi: 10.1186/s12917-020-02432-1.
- Kazuń B., Małaczewska J., Kazuń K., Kamiński R., Żylińska J.: Dietary supplementation with Lactobacillus plantarum and β-glucan affects immune parameters in the tench (Tinca tinca) fry. Pol J Vet Sci 2020, 23, 611–618, doi: 10.24425/pjvs.2020.135808.
- Kazuń B., Małaczewska J., Kazuń K., Żylińska-Urban J., Siwicki A.K.: Immune-enhancing activity of potential probiotic strains of Lactobacillus plantarum in the Common Carp (Cyprinus carpio) fingerling. J Vet Res 2018, 62, 485–492, doi: 10.2478/jvetres-2018-0062.
- Koch J.F.A., de Oliveira C.A.F., Zanuzzo F.S.: Dietary β-glucan (MacroGard®) improves innate immune responses and disease resistance in Nile tilapia regardless of the administration period. Fish Shellfish Immunol 2021, 112, 56–63, doi: 10.1016/j.fsi.2021.02.014.
- Kühlwein H., Merrifield D.L., Rawling M.D., Foey A.D., Davies S.J.: Effects of dietary β-(1,3)(1,6)-D-glucan supplementation on growth performance, intestinal morphology and haemato-immunological profile of mirror carp (Cyprinus carpio L.). Anim Physiol Anim Nutr (Berl) 2014, 98, 279–289, doi: 10.1111/jpn.12078.
- Lin S., Pan Y., Luo L., Luo L.: Effects of dietary β-1,3-glucan, chitosan or raffinose on the growth, innate immunity and resistance of koi (Cyprinus carpio koi). Fish Shellfish Immunol 2011, 31, 788–794, doi: 10.1016/j.fsi.2011.07.0.
- Machuca C., Méndez-Martínez Y., Reyes-Becerril M., Angulo C.: Yeast β-glucans as fish immunomodulators: A review. Animals 2022, 12, 2154, doi: 10.3390/ani12162154.
- Misra C.K., Das B.K., Mukherjee S.C., Pattnaik P.: Effect of long term administration of dietary β-glucan on immunity, growth and survival of Labeo rohita fingerlings. Aquaculture 2006, 255, 82–94, doi: 10.1016/j.aquaculture.2005.12.009.
- Mokhtar D.M., Zaccone G., Alesci A., Kuciel M., Hussein M.T., Sayed R.K.A.: Main components of fish immunity: An overview of the fish immune system. Fishes 2023, 8, 93, doi: 10.3390/fishes8020093.
- Myszkowski L., Kamiński R., Quiros M., Stanny L.A., Wolnicki J.: Diet-influenced growth, size variability, condition and body deformities in juvenile crucian carp Carassius carassius L. reared under controlled conditions. Arch Pol Fish 2002, 10, 51–61, doi: 10.2478/v10086-012-0019-x.
- Neamat-Allah A.N.F., Mahsoub Y.H., Mahmoud E.A.: The potential benefits of dietary β-glucan against growth retardation, immunosuppression, oxidative stress and expression of related genes and susceptibility to Aeromonas hydrophila challenge in Oreochromis niloticus induced by herbicide pendimethalin. Aquacult Res 2021, 52, 518–528, doi: 10.1111/are.14910.
- Nieves-Rodríguez K.N., Álvarez-González C.A., Peña-Marín E.S., Vega-Villasante F., Martínez-García R., Camarillo-Coop S., Tovar-Ramírez D., Guzmán-Villanueva L.T., Andree K.B., Gisbert E.: Effect of β-glucans in giets on growth, survival, digestive enzyme activity, and immune system and intestinal barrier gene expression for Tropical gar (Atractosteus tropicus) juveniles. Fishes 2018, 3, 27, doi: 10.3390/fishes3030027.
- Nowosad J., Abdel-Latif H.M.R., Łuczyński M., Boroń A., Kapusta A., Kujawa R., Przybył A., Kucharczyk D.: Artificial reproduction of vimba bream (Vimba vimba) cultured generation F2 and eggs management under controlled conditions. Aquaculture 2023, 575, 739741, doi: 10.1016/j.aquaculture.2023.739741.
- Pilarski F., de Oliveira C.A.F., de Souza F.P.B.D., Zanuzzo F.S.: Different β-glucans improve the growth performance and bacterial resistance in Nile tilapia. Fish Shellfish Immunol 2017, 70, 25–29, doi: 10.1016/j.fsi.2017.06.059.
- Ringø E., Olsen R.E., Vecino J.L.G., Wadsworth S., Song S.K.: Use of immunostimulants and nucleotides in aquaculture: a review. J Marine Sci Res Dev 2012, 2, 1–22, doi: 10.4172/21559910.1000104.
- Rodrigues M.V., Zanuzzo F.S., Koch J.F.A., de Oliveira C.A.F., Sima P., Vetvicka V.: Development of fish immunity and the role of β-glucan in immune responses. Molecules 2020, 25, 5378, doi: 10.3390/molecules25225378.
- Sabioni R.E., Zanuzzo F.S., Gimbo R.Y., Urbinati E.C.: β-Glucan enhances respiratory activity of leukocytes suppressed by stress and modulates blood glucose levels in pacu (Piaractus mesopotamicus). Fish Physiol Biochem 2020, 46, 629–640, doi: 10.1007/s10695-019-00739-x.
- Selim K.M., Reda R.M.: Beta-glucans and mannan oligosaccharides enhance growth and immunity in Nile Tilapia. N Am J Aquacult 2015, 77, 22–30, doi: 10.1080/15222055.2014.951812.
- Wang W., Sun J., Liu C., Xue Z.: Application of immunostimulants in aquaculture: current knowledge and future perspectives. Aquacult Res 2017, 48, 1–23, doi: 10.1111/are.13161.
- Yoshida T., Kruger R., Inglis V.: Augmentation of non-specific protection in African catfish Clarias gariepinus (Burchell) by the long term oral administration of immunostimulants. J Fish Dis 1995, 18, 195–198, doi: 10.1111/j.1365-2761.1995.tb00278.x.
DOI: https://doi.org/10.2478/jvetres-2026-0023 | Journal eISSN: 2450-8608
Language: English
Page range: 227 - 232
Submitted on: Jul 9, 2025
Accepted on: Apr 16, 2026
Published on: Apr 18, 2026
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Keywords:
Related subjects:
© 2026 Barbara Kazuń, Krzysztof Kazuń, Joanna Małaczewska, Rafał Kaminski, Justyna Sikorska, Jacek Wolnicki, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution 4.0 License.