Fig. 1.
Medians of the studied parameters from peripheral blood (PB) and uterine blood (UB) along with the minimum–maximum range (pg/mL)
| OCP | CCP | C | P-value | |||
|---|---|---|---|---|---|---|
| CRP | PB | 205.8 (16.1 – 310.9) | 36.15 (6.8–304.3) | 7.8 (6.8–10.6) | OCP vs C | 0.0007 |
| CCP vs C | 0.0336 | |||||
| OCP vs CCP | 0.0299 | |||||
| UB | 186.8 (8–310.9) | 168.4 (5–482.5) | 6.6 (5.1–10.1) | CCP vs C | 0.0013 | |
| CCP vs C | 0.0644 | |||||
| OCP vs CCP | 0.6627 | |||||
| P-value | 0.5781 | 0.0728 | ||||
| IL-1α | PB | 22.16 (10.5–33.24) | 26.3 (11.37–210.5) | 5.46 (2.2–16.99) | OCP vs C | 0.008 |
| CCP vs C | 0.0004 | |||||
| OCP vs CCP | 0.1147 | |||||
| UB | 16.91 (11.4–30.57) | 27.03 (9.3–198.7) | 3.015 (0–9.6) | OCP vs C | 0.0007 | |
| CCP vs C | 0.0001 | |||||
| OCP vs CCP | 0.0658 | |||||
| P-value | 0.3828 | 0.9526 | ||||
| IL-1β | PB | 16.2 (6.21–50.62) | 16.17 (7.4–135.2) | 0.215 (0–4.85) | OCP vs C | 0.0007 |
| CCP vs C | 0.0001 | |||||
| OCP vs CCP | 0.5582 | |||||
| UB | 16.92 (8.59–39.56) | 19.66 (5.87–93.15) | 1.15 (0–6.04) | OCP vs C | 0.0007 | |
| CCP vs C | 0.0001 | |||||
| OCP vs CCP | 0.0658 | |||||
| P-value | 0.4609 | 0.9697 | ||||
| IL-6 | PB | 23.55 (11.18–135.1) | 118.2 (7.39–232.5) | 0 (0–5.19) | OCP vs C | 0.0007 |
| CCP vs C | 0.0001 | |||||
| OCP vs CCP | 0.2083 | |||||
| UB | 35.93 (15.99–285.4) | 123.6 (6.39–314.5) | 3.195 (0–11.58) | OCP vs C | 0.0007 | |
| CCP vs C | 0.0005 | |||||
| OCP vs CCP | 0.6378 | |||||
| P-value | 0.0078 | 0.001 | ||||
| IL-10 | PB | 123 (56.71–789) | 161.5 (45.1–979.6) | 60.38 (31.05–145.3) | OCP vs C | 0.0636 |
| CCP vs C | 0.0126 | |||||
| OCP vs CCP | 0.6101 | |||||
| UB | 76.25 (45.71–154.9) | 71.98 (37.77–795.8) | 89.08 (39.6–253.4) | OCP vs C | 0.5728 | |
| CCP vs C | 0.4936 | |||||
| OCP vs CCP | 0.8076 | |||||
| P-value | 0.0078 | 0.0005 |
Medians of morphological and biochemical parameters measured in peripheral blood with the minimum–maximum range
| OCP | CCP | C | Pair-wise comparison | P-value | |
|---|---|---|---|---|---|
| WBC (×109/L) | 21.43 (16.76–24.9) | 19.87 (14.76–24.53) | 7.35 (6.7–8.4) | C vs OCP | 0.0007 |
| C vs CCP | 0.0001 | ||||
| CCP vs OCP | 0.3431 | ||||
| RBC (×1012/L) | 4.9 (4.6–6.1) | 5.2 (3.6–6.6) | 4.8 (4.3–5.8) | CCP vs OCP | 0.4875 |
| C vs CCP | 0.5369 | ||||
| CCP vs OCP | 0.8349 | ||||
| HCT (%) | 45 (31–54) | 43 (28–59) | 45 (33–50) | C vs OCP | 0.9873 |
| C vs CCP | 0.8349 | ||||
| CCP vs OCP | 0.983 | ||||
| HGB (g/dL) | 17.2 (14.7–25.8) | 17.89 (13.7–20.3) | 17.9 (14.9–20.3) | C vs OCP | 0.8765 |
| C vs CCP | 0.7659 | ||||
| CCP vs OCP | 0.6919 | ||||
| ALT (IU) | 51.5 (29–87) | 46.5 (19–95) | 26 (12–31) | C vs OCP | 0.0023 |
| C vs CCP | 0.0075 | ||||
| CCP vs OCP | 0.5073 | ||||
| AST (IU) | 45 (12–54) | 34 (12–64) | 27.5 (18–35) | C vs OCP | 0.0989 |
| C vs CCP | 0.3916 | ||||
| CCP vs OCP | 0.137 | ||||
| ALP (IU) | 82.5 (45–99) | 93.5 (23–152) | 139.5 (129–152) | C vs OCP | 0.0007 |
| C vs CCP | 0.0023 | ||||
| CCP vs OCP | 0.4137 | ||||
| CR (mg/dL) | 1.7 (1.4–1.9) | 1.7 (0.5–2) | 0.95 (0.7–1.2) | C vs OCP | 0.0007 |
| C vs CCP | 0.0486 | ||||
| CCP vs OCP | 0.5045 | ||||
| Urea (mg/dL) | 33 (19–50) | 45.5 (21–59) | 21 (13–41) | C vs OCP | 0.1668 |
| C vs CCP | 0.0014 | ||||
| CCP vs OCP | 0.0358 | ||||
| PLT (109/L) | 361.5 (234–643) | 291 (194–498) | 405 (231–543) | C vs OCP | 0.7546 |
| C vs CCP | 0.1712 | ||||
| CCP vs OCP | 0.3144 |