Establishment of primary cell cultures from canine mammary gland malignant tumours: a preliminary study
By:
References
- Abdelmegeed S.M., Mohammed S.: Canine mammary tumors as a model for human disease. Oncol Lett 2018, 15, 8195–8205, doi: 10.3892/ol.2018.8411.
- Baba A.I., Câtoi C.: Chapter 11 Mammary Gland Tumors. In:
Comparative Oncology . The Publishing House of the Romanian Academy, Bucharest, Romania, 2007. - Barak V., Goike H., Panaretakis K.W., Einarsson R.: Clinical utility of cytokeratins as tumor markers. Clin Biochem 2004, 37, 529–540, doi: 10.1016/j.clinbiochem.2004.05.009.
- Benavente M.A., Bianchi C.P., Aba M.A.: Canine Mammary Tumors: Risk Factors, Prognosis and Treatments. J Vet Adv 2016, 6, 1291–1300, doi: 10.5455/jva.20160916045115.
- Brunetti B., Bacci B., Angeli C., Benazzi C., Muscatello L.V.: p53, ER, and Ki67 Expression in Canine Mammary Carcinomas and Correlation With Pathological Variables and Prognosis. Vet Pathol 2021, 58, 325–331, doi: 10.1177/0300985820973462.
- Caceres S., Peña L., de Andres P.J., Illera M.J., Lopez M.S., Woodward W.A., Reuben J.M.: Establishment and characterization of a new cell line of canine inflammatory mammary cancer: IPC-366. PLoS One 2015, 10, e0122277, doi: 10.1371/journal.pone.0122277.
- Chen A., Ye S., Zheng J., Li J., Chen Z., Zhang Y., Li S.: Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line. BMC Vet Res 2023, 19, 22, doi: 10.1186/s12917-023-03573-9.
- Davis B.W., Ostrander E.A.: Domestic Dogs and Cancer Research: A Breed-Based Genomics Approach. ILAR J 2014, 55, 59–68, doi: 10.1093/ilar/ilu017.
- de Oliveira J.T., Pinho S.S., de Matos A.J., Hespanhol V., Reis C.A., Gärtner, F.: MUC1 expression in canine malignant mammary tumours and relationship to clinicopathological features. Vet J 2009, 182, 491–493, doi: 10.1016/j.tvjl.2008.09.007.
- Dominguez P.A., Dervisis N.G., Cadile C.D., Sarbu L., Kitchell B.E.: Combined gemcitabine and carboplatin therapy for carcinomas in dogs. J Vet Intern Med 2009, 23, 130–137, doi: 10.1111/j.1939-1676.2008.0248.x.
- Gao H., Zhou H., Gao Y., He L., Li W., Xu M., Feng H., Feng X., Qui Ch.: Establishment of a new cell line of canine inflammatory mammary cancer: IMC-118. Vet Comp Oncol 2022, 20, 679–687, doi: 10.1111/vco.12822.
- Guillen-Poza P.A., Sánchez-Fernández E.M., Artigas G., García Fernández J.M., Hinou H., Mellet C.O., Nishimura S.-I., Garcia-Martin F.: Amplified detection of breast cancer autoantibodies using MUC1-based Tn antigen mimics. J Med Chem 2020, 63, 8524–8533, doi: 10.1021/acs.jmedchem.0c00908.
- Hashmi A.A., Naz S., Hashmi S.K., Hussain Z.F., Irfan M., Abu Bakar S.M., Faridi N., Khan A., Edhi M.M.: Cytokeratin 5/6 and cytokeratin 8/18 expression in triple negative breast cancers: clinicopathologic significance in South-Asian population. BMC Res Notes 2018, 11, 372, doi: 10.1186/s13104-018-3477-4.
- Henry C.J.: Biomarkers in veterinary cancer screening: Applications, limitations and expectations. Vet J 2010, 185, 10–14, doi: 10.1016/j.tvjl.2010.04.005.
- Kaszak I., Ruszczak A., Kanafa S., Kacprzak K., Król M., Jurka P.: Current biomarkers of canine mammary tumors. Acta Vet Scand 2018, 60, 66, doi: 10.1186/s13028-018-0417-1.
- Król M., Pawłowski K.M., Szyszko K., Maciejewski H., Dolka I., Manuali E., Jank M., Motyl T.: The gene expression profiles of canine mammary cancer cells grown with carcinoma-associated fibroblasts (CAFs) as a co-culture
in vitro . BMC Vet Res 2012, 8, 35, doi: 10.1186/1746-6148-8-35. - Lainetti P. de F., Brandi A., Leis Filho A.F., Prado M.C.M., Kobayashi P.E., Laufer-Amorim R., Fonseca-Alves C.E.: Establishment and characterization of canine mammary gland carcinoma cell lines with vasculogenic mimicry ability
in vitro andin vivo . Front Vet Sci 2020, 7, 583874, doi: 10.3389/fvets.2020.583874. - Li R., Wu H., Sun Y., Zhu J., Tang J., Kuang Y., Li G.: A novel canine mammary cancer cell line: preliminary identification and utilization for drug screening studies. Front Vet Sci 2021, 8, 665906, doi: 10.3389/fvets.2021.665906.
- Liu Y., Hu T., Shen J., Li S.F., Lin J.W., Zheng X.H., Gao Q.H., Zhou H.M.: Separation, cultivation and biological characteristics of oral carcinoma-associated fibroblasts. Oral Dis 2006, 12, 375–380, doi: 10.1111/j.1601-0825.2005.01207.x.
- Manuali E., De Giuseppe A., Feliziani F., Forti K., Casciari C., Marchesi M.Ch., Pacifico E., Pawłowski K.M., Majchrzak K., Król M.: CA 15-3 cell lines and tissue expression in canine mammary cancer and the correlation between serum levels and tumour histological grade. BMC Vet Res 2012, 8, 86, doi: 10.1186/1746-6148-8-86.
- Marchesi M., Manuali E., Pacifico E., Ferri C., Romagnoli M., Mangili V., Fruganti G.: Cancer antigen 15/3: possible diagnostic use in veterinary clinical oncology. Preliminary study. Vet Res Commun 2010, 34, 103–106, doi: 10.1007/s11259-010-9392-3.
- Mei C., Xin L., Liu Y., Lin J., Xian H., Zhang X., Hu W., Xia Z., Wang H., Lyu Y.: Establishment of a New Cell Line of Canine Mammary Tumor CMT-1026. Front Vet Sci 2021, 8, 744032, doi: 10.3389/fvets.2021.744032.
- Misdorp W.: Volume 7, Histological classification of mammary tumors of the dog and the cat. In:
International Histological Classification of Domestic Animals, Second Series , Armed Forces Institute of Pathology, American Registry of Pathology, World Health Organization Collaborating Center for Worldwide Reference on Comparative Oncology, Washington, D.C., 1999. - Muniappan N., Ramesh S., Hemalatha S., Shafiuzama M., Preetha S.P.: Expression of Biomarkers in Canine Mammary Tumours. Int J Curr Microbiol App Sci 2019, 8, 1464–1473, doi: 10.20546/ijcmas.2019.805.168.
- Nguyen F., Peña L., Ibisch C., Loussouarn D., Gama A., Rieder N., Belousov A., Campone M., Abadie J.: Canine invasive mammary carcinomas as models of human breast cancer. Part 1: natural history and prognostic factors. Breast Cancer Res Treat 2018, 167, 635–648, doi: 10.1007/s10549-017-4548-2.
- Nowak M., Madej J.A., Pula B., Dzięgiel P., Ciaputa R.: Expression of matrix metalloproteinase 2 (MMP-2), E-cadherin and Ki-67 in metastatic and non-metastatic canine mammary carcinomas. Ir Vet J 2016, 69, 9, doi: 10.1186/s13620-016-0068-3.
- Peña L.L., Nieto A.I., Pérez-Alenza D., Cuesta P., Castaño M.: Immunohistochemical detection of Ki-67 and PCNA in canine mammary tumors: relationship to clinical and pathologic variables. J Vet Diagn Invest 1998, 10, 237–246, doi: 10.1177/104063879801000303.
- Rasotto R., Goldschmidt M.H., Castagnaro M., Carnier P., Caliari D., Zappulli V.: The dog as a natural animal model for study of the mammary myoepithelial basal cell lineage and its role in mammary carcinogenesis. J Comp Pathol 2014, 151, 166–180, doi: 10.1016/j.jcpa.2014.04.013.
- Rezaie A., Tavasoli A., Mehrazma M., Bahonar A.: Immuno-histochemical staining expression of Ki67 protein in canine mammary gland carcinoma. Comp Clin Path 2010, 20, 557–561, doi: 10.1007/s00580-010-1032-3.
- Richter M., Piwocka O., Musielak M., Piotrowski I., Suchorska W.M., Trzeciak T.: From donor to the lab: a fascinating journey of primary cell lines. Front Cell Dev Biol 2021, 9, 711381, doi: 10.3389/fcell.2021.711381.
- Sammarco A., Gomiero C., Beffagna G., Cavicchioli L., Ferro S., Michieletto S., Orvieto E., Patruno M., Zappulli V.: Epithelial-to-mesenchymal transition and phenotypic marker evaluation in human, canine, and feline mammary gland tumors. Animals 2023, 13, 878, doi: 10.3390/ani13050878.
- Schindelin J., Arganda-Carreras I., Frise E., Kaynig V., Longair M., Pietzsch T., Preibisch S., Rueden C., Saalfeld S., Schmid B., Tinevez J.-Y., White D.J., Hartenstein V., Eliceiri K., Tomancak P., Cardona A.: Fiji: an open-source platform for biological-image analysis. Nat Methods 2012, 9, 676–682, doi: 10.1038/nmeth.2019.
- Sorenmo K.U., Worley D.R., Zappulli V.: Tumors of the Mammary Gland. In:
Withrow and MacEwen’s Small Animal Clinical Oncology , Sixth Edition, edited by D.M. Vail, D.H. Thamm, J.M. Liptak. W.B. Saunders, St. Louis, MO, USA, 2019, pp 604-625. - Stephens T.: The use of chemotherapy to prolong the life of dogs suffering from cancer: the ethical dilemma. Animals 2019, 9, 441, doi: 10.3390/ani9070441.
- Tran C.M., Moore A.S., Frimberger A.E.: Surgical treatment of mammary carcinomas in dogs with or without postoperative chemotherapy. Vet Comp Oncol 2016, 14, 252–262, doi: 10.1111/vco.12092.
- Zhang H., Pei S., Zhou B., Wang H., Du H., Zhang D., Lin D.: Establishment and characterization of a new triple-negative canine mammary cancer cell line. Tissue Cell 2018, 54, 10–19, doi: 10.1016/j.tice.2018.07.003.
- Zhao Y., Lin Z., Lin Z., Zhou Ch., Liu G., Lin J., Zhang D., Lin D.: Overexpression of mucin 1 suppresses the therapeutical efficacy of disulfiram against canine mammary tumor. Animals 2021, 11, 37, doi: 10.3390/ani11010037.
- Zhou B., Chen W.-L., Wang Y.-Y., Lin Z.-Y., Zhang D.-M., Fan S., Li J.-S.: A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma. J Oral Pathol Med 2014, 43, 585–592, doi: 10.1111/jop.12172.
- Zuccari D.A.P.C., Santana A.E., Cury P.M., Cordeiro J.A.: Immunocytochemical study of Ki-67 as a prognostic marker in canine mammary neoplasia. Vet Clin Pathol 2004, 33, 23–28, doi 10.1111/j.1939-165X.2004.tb00345.x.
DOI: https://doi.org/10.2478/jvetres-2025-0007 | Journal eISSN: 2450-8608
Language: English
Page range: 159 - 168
Submitted on: Jul 17, 2024
Accepted on: Feb 10, 2025
Published on: Mar 1, 2025
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
Related subjects:
© 2025 Patŕicia Petrouškova, Nikola Hudáková, Viera Almášiová, Alexandra Valenčáková, L’ubica Horňáková, Mykhailo Huniadi, Daša Čížková, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution 4.0 License.