Have a personal or library account? Click to login
Development of a method for the determination of sedatives in bovine and porcine urine and kidneys by liquid chromatography–tandem mass spectrometry Cover

Development of a method for the determination of sedatives in bovine and porcine urine and kidneys by liquid chromatography–tandem mass spectrometry

Open Access
|Mar 2024

References

  1. Bock C., Stachel C.S.: Development and validation of a confirmatory method for the determination of tranquilisers and a β-blocker in porcine and bovine kidney by LC-MS/MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2013, 30, 1000–1011, doi: <a href="https://doi.org/10.1080/19440049.2013.795292." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1080/19440049.2013.795292.</a>
  2. Cerkvenik-Flajs V.: Determination of residues of azaperone in the kidneys by liquid chromatography with fluorescence detection. Anal Chim Acta 2007, 586, 374–382, doi: <a href="https://doi.org/10.1016/j.aca.2006.11.010." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.aca.2006.11.010.</a>
  3. Cheng J.-Q., Liu T., Nie X.-M., Chen F.-M., Wang C.-S., Zhang F.: Analysis of 27 β-Blockers and Metabolites in Milk Powder by High Performance Liquid Chromatography Coupled to Quadrupole Orbitrap High-Resolution Mass Spectrometry. Molecules 2019, 24, 820, doi: <a href="https://doi.org/10.3390/molecules24040820." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3390/molecules24040820.</a>
  4. Choi J.-H., Lamshöft M., Zühlke S., Park J.-H., Rahman M.M., Abd El-Aty A.M., Spiteller M., Shim J.-H.: Determination of anxiolytic veterinary drugs from biological fertilizer blood meal using liquid chromatography high-resolution mass spectrometry. Biomed Chromatogr 2014, 28, 751–759, doi: <a href="https://doi.org/10.1002/bmc.30." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1002/bmc.30.</a>
  5. Commission of the European Communities: Commission Decision 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. OJEC, 17/8/2002, L 221, 45, 8–36.
  6. Cooper J., Delahaut P., Fodey T.L., Elliott C.T.: Development of a rapid screening test for veterinary sedatives and the beta-blocker carazolol in porcine kidney by ELISA. Analyst 2004, 129, 169–174, doi: <a href="https://doi.org/10.1039/b311709j." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1039/b311709j.</a>
  7. Delahaut P., Levaux C., Eloy P., Dubois M.: Validation of a method for detecting and quantifying tranquillisers and a β-blocker in pig tissues by liquid chromatography-tandem mass spectrometry. Anal Chim Acta 2003, 483, 335–340, doi: <a href="https://doi.org/10.1016/S0003-2670(02)01024-3." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/S0003-2670(02)01024-3.</a>
  8. Ebrahimzadeh H., Dehghani Z., Asgharinezhad A.-A., Shekari N., Molaei K.: Determination of haloperidol in biological samples with the aid of ultrasound-assisted emulsification microextraction followed by HPLC-DAD. J Sep Sci 2013, 36, 1597–1603, doi: <a href="https://doi.org/10.1002/jssc.201201099." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1002/jssc.201201099.</a>
  9. European Commission: Commission Regulation (EU) No 37/2010 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin. OJEU 20/1/2010, L 15, 53, 1–72.
  10. European Commission: Commission Implementing Regulation (EU) 2021/808 of 22 March 2021 on the performance of analytical methods for residues of pharmacologically active substances used in food-producing animals and on the interpretation of results as well as on the methods to be used for sampling and repealing Decisions 2002/657/EC and 98/179/EC. OJEU 21/5/2021, L 180, 64, 112–113.
  11. European Commission: Commission Delegated Regulation (EU) 2022/1644 of 7 July 2022 supplementing Regulation (EU) 2017/625 of the European Parliament and of the Council with specific requirements for the performance of official controls on the use of pharmacologically active substances authorised as veterinary medicinal products or as feed additives and of prohibited or unauthorised pharmacologically active substances and residues thereof. OJEU 26/9/2022, L 248, 65, 3–17.
  12. European Commission: Commission Implementing Regulation (EU) 2022/1646 of 23 September 2022 on uniform practical arrangements for the performance of official controls as regards the use of pharmacologically active substances authorised as veterinary medicinal products or as feed additives and of prohibited or unauthorised pharmacologically active substances and residues thereof, on specific content of multi-annual national control plans and specific arrangements for their preparation. OJEU 26/9/2022, L 248, 65, 32–45.
  13. European Parliament and the Council of the European Union: Regulation (EU) 2017/625 of the European Parliament and of the Council of 15 March 2017 on official controls and other official activities performed to ensure the application of food and feed law, rules on animal health and welfare, plant health and plant protection products, amending Regulations (EC) No 999/2001, (EC) No 396/2005, (EC) No 1069/2009, (EC) No 1107/2009, (EU) No 1151/2012, (EU) No 652/2014, (EU) 2016/429 and (EU) 2016/2031 of the European Parliament and of the Council, Council Regulations (EC) No 1/2005 and (EC) No 1099/2009 and Council Directives 98/58/EC, 1999/74/EC, 2007/43/EC, 2008/119/EC and 2008/120/EC, and repealing Regulations (EC) No 854/2004 and (EC) No 882/2004 of the European Parliament and of the Council, Council Directives 89/608/EEC, 89/662/EEC, 90/425/EEC, 91/496/EEC, 96/23/EC, 96/93/EC and 97/78/EC and Council Decision 92/438/EEC. OJEU 7/4/2017, L 95, 60, 1–142.
  14. European Union Reference Laboratories: Guidance on minimum method performance requirements (MMPRs) for specific pharmacologically active substances in specific animal matrices Version 2.0, June 2022. EURL, Wageningen University & Research, Wageningen, 2022.
  15. Flieger J., Tatarczak-Michalewska M., Kowalska A., Madejska A, Śniegocki T., Sroka-Bartnicka A., Szymańska-Chargot M.: Effective phospholipid removal from plasma samples by solid phase extraction with the use of copper (II) modified silica gel cartridges. J Chromatogr B Analyt Technol Biomed Life Sci 2017, 1070, 1–6, doi: <a href="https://doi.org/10.1016/j.jchromb.2017.10.021." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.jchromb.2017.10.021.</a>
  16. Gbylik-Sikorska M., Posyniak A., Sniegocki T., Zmudzki J.: Liquid chromatography-tandem mass spectrometry multiclass method for the determination of antibiotics residues in water samples from water supply systems in food-producing animal farms. Chemosphere 2015, 119, 8–15, doi: <a href="https://doi.org/10.1016/j.chemosphere.2014.04.105." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.chemosphere.2014.04.105.</a>
  17. Ginkel L.A.V., Schwillens P.L.W.J., Olling M.: Liquid chromatographic method with on-line UV spectrum identification and off-line thin-layer chromatographic confirmation for the detection of tranquillizers and carazolol in pig kidneys. Analytica Chimica Acta 1989, 225, 137–146, doi: <a href="https://doi.org/10.1016/S0003-2670(00)84602-4." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/S0003-2670(00)84602-4.</a>
  18. Haagsma N., Bathelt E.R., Engelsma J.W.: Thin-layer chromatographic screening method for the tranquillizers azaperone, propiopromazine and carazolol in pig tissues. J Chromatogr 1988, 436, 73–79, doi: <a href="https://doi.org/10.1016/s0021-9673(00)94567-9." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/s0021-9673(00)94567-9.</a>
  19. Hoogland H., Beek W.M.J., Keukens H.J., Aerts M.M.L.: Confirmation of tranquillizers in porcine kidney by GC-MS. Arch Lebensmittelhyg 1991, 42, 79–83.
  20. Kaufmann A., Ryser B.: (2001). Multiresidue analysis of tranquilizers and the beta-blocker Carazolol in meat by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2001, 15, 1747–1751, doi: <a href="https://doi.org/10.1002/rcm.393." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1002/rcm.393.</a>
  21. Keukens H.J., Aerts M.M.L.: Determination of residues of carazolol and a number of tranquillizers in swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection. J Chromatog 1989, 464, 149–161, doi: <a href="https://doi.org/10.1016/s0021-9673(00)94231-6." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/s0021-9673(00)94231-6.</a>
  22. Kośka I., Kubalczyk P.: Development of the Chromatographic Method for Simultaneous Determination of Azaperone and Azaperol in Animal Kidneys and Livers. Int J Mol Sci 2022, 24, 100, doi: <a href="https://doi.org/10.3390/ijms24010100." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3390/ijms24010100.</a>
  23. López-García E., Mastroianni N., Postigo C., Barceló D., López de Alda M.: A fully automated approach for the analysis of 37 psychoactive substances in raw wastewater based on on-line solid phase extraction-liquid chromatography-tandem mass spectrometry. J Chromatogr A 2018, 1576, 80–89, doi: <a href="https://doi.org/10.1016/j.chroma.2018.09.038." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.chroma.2018.09.038.</a>
  24. Mendes L.F., Rodrigues Souza e Silva A., Bacil R.P., Pires Serrano S.H., Angnes L., Paixão T.R.L.C., Reis de Araujo W.: Forensic electrochemistry: Electrochemical study and quantification of xylazine in pharmaceutical and urine samples. Electrochimica Acta 2019, 295, 726–734, doi: <a href="https://doi.org/10.1016/j.electacta.2018.10.120." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.electacta.2018.10.120.</a>
  25. Mitrowska K., Posyniak A., Zmudzki J.: Rapid method for the determination of tranquilizers and a beta-blocker in porcine and bovine kidney by liquid chromatography with tandem mass spectrometry. Anal Chim Acta 2009, 637, 185–92, doi: <a href="https://doi.org/10.1016/j.aca.2008.10.030." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.aca.2008.10.030.</a>
  26. Olmos-Carmona M.L., Hernández-Carrasquilla M.: Gas chromatographic-mass spectrometric analysis of veterinary tranquillizers in urine: evaluation of method performance. J Chromatogr B Biomed Sci Appl 1999, 734, 113–120, doi: <a href="https://doi.org/10.1016/s0378-4347(99)00334-5." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/s0378-4347(99)00334-5.</a>
  27. Sanagi M.M., Hanapi N.S.M., Ismail A.K., Ibrahim W.A.W., Saim N., Yahaya N.: Two-phase electrodriven membrane extraction combined with liquid chromatography for the determination of tricyclic antidepressants in aqueous matrices. Anal Methods 2014, 6, 8802–8809, doi: <a href="https://doi.org/10.1039/C4AY01700E." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1039/C4AY01700E.</a>
  28. Shang J., He X., Xi C., Tang B., Wang G., Chen D., Peng T., Mu Z.: Determination of the potential illegal addition of β-blockers to function foods by QuEChERS sample preparation and UPLC-MS/MS analysis. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2015, 32, 1040–1048, doi: <a href="https://doi.org/10.1080/19440049.2015.1042073." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1080/19440049.2015.1042073.</a>
  29. Sun S., Zhu L., Hu Y., Liu Y., Xu L.: Determination of sedative and β-receptor hormone residues in feed by ultra high performance liquid chromatography-tandem mass spectrometry. Chin J Chromatogr 2018, 36, 150–158, doi: <a href="https://doi.org/10.3724/SP.J.1123.2017.10025." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3724/SP.J.1123.2017.10025.</a>
  30. Śniegocki T., Gbylik-Sikorska M., Posyniak A.: Analytical Strategy for Determination of Chloramphenicol in Different Biological Matrices by Liquid Chromatography - Mass Spectrometry. J Vet Res 2017, 61, 321–327, doi: <a href="https://doi.org/10.1515/jvetres-2017-0032." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1515/jvetres-2017-0032.</a>
  31. Śniegocki T., Gbylik-Sikorska M., Posyniak A., Zmudzki J.: Determination of carbadox and olaquindox metabolites in swine muscle by liquid chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2014, 944, 25–29, doi: <a href="https://doi.org/10.1016/j.jchromb.2013.09.039." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.jchromb.2013.09.039.</a>
  32. Śniegocki T., Giergiel M., Sell B., Posyniak A.: New Method of Analysis of Nitrofurans and Nitrofuran Metabolites in Different Biological Matrices Using UHPLC-MS/MS. J Vet Res 2018, 62, 161–166, doi: <a href="https://doi.org/10.2478/jvetres-2018-0025." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.2478/jvetres-2018-0025.</a>
  33. Śniegocki T., Sell B., Giergiel M., Posyniak A.: QuEChERS and HPLC-MS/MS Combination for the Determination of Chloramphenicol in Twenty Two Different Matrices. Molecules 2019, 24, 384, doi: <a href="https://doi.org/10.3390/molecules24030384." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3390/molecules24030384.</a>
  34. Śniegocki T., Sell B., Posyniak A.: Analysis of β-agonists in Different Biological Matrices By Liquid Chromatography-tandem Mass Spectrometry. J Vet Res 2021, 65, 469–475, doi: <a href="https://doi.org/10.2478/jvetres-2021-0058." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.2478/jvetres-2021-0058.</a>
  35. Wang Y., Li X., Ke Y., Wang C., Zhang Y., Ye D., Hu X., Zhou L., Xia X.: Determination of Tranquilizers in Swine Urine by Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Molecules 2018, 23, 3215, doi: <a href="https://doi.org/10.3390/molecules23123215." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3390/molecules23123215.</a>
  36. Wei J., Luo Y., Zhang L., Fang S.: Determination of 15 sedative residues in mutton by rapid resolution liquid chromatography-tandem mass spectrometry. J Sci Food Agric 2015, 95, 598–606, doi: <a href="https://doi.org/10.1002/jsfa.6794." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1002/jsfa.6794.</a>
  37. Wozniak B., Matraszek-Żuchowska I., Kłopot A., Posyniak A.: Fast analysis of 19 anabolic steroids in bovine tissues by high performance liquid chromatography with tandem mass spectrometry. J Sep Sci 2019, 42, 3319–3329, doi: <a href="https://doi.org/10.1002/jssc.201900494." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1002/jssc.201900494.</a>
  38. Xiao X., Zhang M., Wang Z.: Determination of β-blockers in bovine and porcine tissues and bovine milk by high-performance liquid chromatography – tandem mass spectrometry. Anal Lett 2019, 52, 439–451, doi: <a href="https://doi.org/10.1080/00032719.2018.1470638." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1080/00032719.2018.1470638.</a>
  39. Zhang J., Shao B., Yin J., Wu Y., Duan H.: Simultaneous detection of residues of β-adrenergic receptor blockers and sedatives in animal tissues by high-performance liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2009, 877, 1915–1922, doi: <a href="https://doi.org/10.1016/j.jchromb.2009.05.025." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.1016/j.jchromb.2009.05.025.</a>
  40. Zhu L., Ruan L., Liu H., Ji W., Ma Y.: Simultaneous determination of 23 sedative drugs in health foods by high performance liquid chromatography-tandem mass spectrometry. Se Pu 2013, 31, 709–713, doi: <a href="https://doi.org/10.3724/sp.j.1123.2012.12025." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3724/sp.j.1123.2012.12025.</a>
  41. Zou Y., Shao L., Chen S., Ouyang S., Lin F.: Determination of three tranquillizer residues in animal foods by QuEChERS-high performance liquid chromatography-tandem mass spectrometry. Se Pu 2017, 35, 801–807, doi: <a href="https://doi.org/10.3724/SP.J.1123.2017.03043." target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">10.3724/SP.J.1123.2017.03043.</a>
Language: English
Page range: 137 - 145
Submitted on: Aug 17, 2023
Accepted on: Jan 4, 2024
Published on: Mar 23, 2024
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year

© 2024 Tomasz Śniegocki, Elżbieta Samorek, Bartosz Sell, Weronika Krajewska, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.