Baseline characteristics in groups of brachycephalic obstructive airway syndrome patients and control group
| Control | Grade 1 | Grade 2 | Grade 3 | |
|---|---|---|---|---|
| Number | 9 | 5 | 16 | 13 |
| Sex (female/male) | 4/5 | 3/2 | 5/11 | 6/7 |
| Age (years) Median; IQR | 3.25; 1.84–3.96 | 3.75; 1.08–6.96 | 2.88; 1.14–7.11 | 1.75; 1.46–8.88 |
| Weight (kg) Median; IQR | 9.50; 8.45–11.25 | 9.56; 5.75–11.54 | 10.20; 7.78–12.53 | 9.60; 8.37–10.70 |
| BCS Median; IQR | 3.0; 3.0–3.5 | 3.0; 2.5–3.5 | 3.0; 3.0–4.0 | 3.0; 3.0–3.0 |
Clinical signs (mean) in groups of brachycephalic obstructive airway syndrome patients before and after surgery
| Respiratory signs | Gastrointestinal signs | Exercise intolerance | Sleep disorders | |
|---|---|---|---|---|
| Grade 1 | ||||
| Before surgery | 3.1 | 1.8 | 2.1 | 3.7 |
| After surgery | 1.5 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 1.2 | 1.0 | 2.0 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present |
| Grade 2 | ||||
| Before surgery | 3.2 | 2.3 | 1.8 | 4.1 |
| After surgery | 1.8 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 1.6 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 1.5 | 2.4 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present |
| Grade 3 | ||||
| Before surgery | 3.1 | 2.1 | 1.8 | 3.8 |
| After surgery | 1.9 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 1.4 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 1.2 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present | 2.7 Significant (P < 0.05) difference in comparison to values before surgery 1.0 means that the clinical sign was not present and 5.0 means that the clinical sign was always present |
Oxidative stress parameters (mean ± standard deviation) in groups of brachycephalic obstructive airway syndrome patients before and after surgery and in the control group
| SOD (U/g Hgb) | GPX (U/g Hgb) | MDA (μmol/L) | |
|---|---|---|---|
| Grade 1 | |||
| Before surgery | 1821.1 ± 155.9 significant (P < 0.05) difference in comparison to activity determined in grade 2 and 3 groups before surgery | 451.7 ± 41.3 | 6.06 ± 1.80 |
| After surgery | 1816.5 ± 116.1 | 460.0 ± 49.9 | 6.37 ± 1.11 |
| Grade 2 | |||
| Before surgery | 1554.4 ± 200.1 | 454.3 ± 83.1 | 6.68 ± 1.02 |
| After surgery | 1593.7 ± 207.4 significant (P < 0.05) difference in comparison to activity before surgery | 466.0 ± 76.7 | 6.49 ± 0.89 |
| Grade 3 | |||
| Before surgery | 1543.1 ± 222.3 | 508.2 ± 97.6 | 6.53 ± 1.62 |
| After surgery | 1683.2 ± 222.8 significant (P < 0.05) difference in comparison to activity before surgery | 504.8 ± 80.8 | 6.22 ± 1.12 |
| Control | 1625.1 ± 280.4 | 501.7 ± 73.5 | 6.92 ± 0.97 |