References
- Teshome MK, Najib K, Nwagbara CC, Akinseye OA, Ibebuogu UN. Patent foramen ovale: a comprehensive review. Curr Probl Cardiol. 2020;45(2):100392. doi: 10.1016/j.cpcardiol.2018.08.004
- Schoenwolf GC. Larsen’s human embryology. 6th ed. Elsevier; 2021.
- Sadler TW. Langman’s medical embryology. 14th ed. Wolters Kluwer Health; 2018.
- Jensen B, Spicer DE, Sheppard MN, Anderson RH. Development of the atrial septum in relation to postnatal anatomy and interatrial communications. Heart. 2017;103(6):456-462. doi: 10.1136/heartjnl-2016-310660
- Rojas CA, et al. Embryology and developmental defects of the interatrial septum. AJR Am J Roentgenol. 2010;195(5):1100-1104. doi: 10.2214/AJR.10.4277
- Anderson RH, Brown NA, Webb S. Development and structure of the atrial septum. Heart. 2002;88(1):104-110. doi: 10.1136/heart.88.1.104
- Naqvi N, McCarthy KP, Ho SY. Anatomy of the atrial septum and interatrial communications. J Thorac Dis. 2018;10(Suppl 24):S2837-S2847. doi: 10.21037/jtd.2018.02.18
- Rojas CA, et al. Embryology and developmental defects of the interatrial septum. AJR Am J Roentgenol. 2010;195(5):1100-1104. doi: 10.2214/AJR.10.4277
- Marshall AC, Lock JE. Structural and compliant anatomy of the patent foramen ovale in patients undergoing transcatheter closure. Am Heart J. 2000;140(2):303-307. doi: 10.1067/mhj.2000.108236
- Hagen PT, Scholz DG, Edwards WD. Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts. Mayo Clin Proc. 1984;59(1):17-20. doi: 10.1016/S0025-6196(12)60336-X
- Ho SY, McCarthy KP, Rigby ML. Morphological features pertinent to interventional closure of patent foramen ovale. J Interv Cardiol. 2003;16(1):33-38. doi: 10.1046/j.1540-8183.2003.08000.x
- Rana BS, Thomas MR, Calvert PA, Monaghan MJ, Hildick-Smith D. Echocardiographic evaluation of patent foramen ovale prior to device closure. JACC Cardiovasc Imaging. 2010;3(7):749-760. doi: 10.1016/j.jcmg.2010.01.007
- Rana BS, Shapiro LM, McCarthy KP, Ho SY. Three-dimensional imaging of the atrial septum and patent foramen ovale anatomy: defining the morphological phenotypes of patent foramen ovale. Eur J Echocardiogr. 2010;11(10):119-i25. doi: 10.1093/ejechocard/jeq122
- Overell JR, Bone I, Lees KR. Interatrial septal abnormalities and stroke: a meta-analysis of case-control studies. Neurology. 2000;55(8):1172-1179. doi: 10.1212/WNL.55.8.1172
- Hanley PC, et al. Diagnosis and classification of atrial septal aneurysm by two-dimensional echocardiography: report of 80 consecutive cases. J Am Coll Cardiol. 1985;6(6):1370-1382. doi: 10.1016/S0735-1097(85)80228-X
- Pearson AC, Nagelhout D, Castello R, Gomez CR, Labovitz AJ. Atrial septal aneurysm and stroke: a transesophageal echocardiographic study. J Am Coll Cardiol. 1991;18(5):1223-1229. doi: 10.1016/0735-1097(91)90539-L
- Rigatelli G, et al. Migraine-patent foramen ovale connection: role of prominent eustachian valve and large Chiari network in migrainous patients. Am J Med Sci. 2008;336(6):458-461. doi: 10.1097/MAJ.0b013e31816e189d
- Schuchlenz HW, Saurer G, Weihs W, Rehak P. Persisting eustachian valve in adults: relation to patent foramen ovale and cerebrovascular events. J Am Soc Echocardiogr. 2004;17(3):231-233. doi: 10.1016/j.echo.2003.12.003
- Schneider B, Hofmann T, Justen MH, Meinertz T. Chiari’s network: normal anatomic variant or risk factor for arterial embolic events? J Am Coll Cardiol. 1995;26(1):203-210. doi: 10.1016/0735-1097(95)00144-O
- Butera G, Montinaro A, Carminati M. The “pull-push” technique to deal with a redundant eustachian valve interfering with placement of a PFO occluder. Catheter Cardiovasc Interv. 2006;68(6):961-964. doi: 10.1002/ccd.20903
- Windecker S, Stortecky S, Meier B, et al. Comparison of medical treatment with percutaneous closure of patent foramen ovale in patients with cryptogenic stroke. J Am Coll Cardiol. 2004;44(4):750-758. doi: 10.1016/j.jacc.2004.05.044
- Turner M, et al. Patent foramen ovale closure: British Cardiovascular Intervention Society position statement. Interv Cardiol(Lond). 2025;20:e04. doi: 10.15420/ICR.2024.18
- Silvestry FE, Cohen MS, Armsby LB, et al. Guidelines for the echocardiographic assessment of atrial septal defect and patent foramen ovale: from the American Society of Echocardiography and Society for Cardiac Angiography and Interventions. J Am Soc Echocardiogr. 2015;28(8):910-958. doi: 10.1016/j.echo.2015.05.015
- Tobe J, Bogiatzi C, Munoz C, Tamayo A, Spence JD. Transcranial Doppler is complementary to echocardiography for detection and risk stratification of patent foramen ovale. Can J Cardiol. 2016;32(8):986.e9-986.e16. doi: 10.1016/j.cjca.2015.12.009
- Komar M, et al. Transcranial Doppler ultrasonography: should it be the first choice for persistent foramen ovale screening? Cardiovasc Ultrasound. 2014;12:16. doi: 10.1186/1476-7120-12-16
- Hutayanon P, Muengtaweepongsa S. The role of transcranial Doppler in detecting patent foramen ovale. J Vasc Ultrasound. 2023;47(1):33-39. doi: 10.1177/15443167221108512
- Van der Giessen H, Wilson LC, Coffey S, Whalley GA. Detection of patent foramen ovale using transcranial Doppler or standard echocardiography. Australas J Ultrasound Med. 2020;23(4):210-218. doi: 10.1002/ajum.12232
- Pristipino C, Sievert H, D’Ascenzo F, et al. European position paper on the management of patients with patent foramen ovale. EuroIntervention. 2019;14(13):1389-1402. doi: 10.4244/EIJ-D-18-00622
- Incedayi M, et al. The incidence of left atrial diverticula in coronary CT angiography. Diagn Interv Radiol. 2012;18(6):542-546. doi: 10.4261/1305-3825.DIR.5388-11.1
- Cademartiri F, Mollet NR, Lemos PA, et al. Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser. Eur Radiol. 2004;14(2):178-183. doi: 10.1007/s00330-003-2188-x
- Yoo J, et al. Frequency and risk of preclinical coronary artery disease detected using multichannel cardiac computed tomography in patients with ischemic stroke. Cerebrovasc Dis. 2012;33(3):286-294. doi: 10.1159/000334980
- Lee S, et al. The role of cardiac CT throughout the full cardiac cycle in diagnosing patent foramen ovale in patients with acute stroke. Eur Radiol. 2021;31(12):8983-8990. doi: 10.1007/s00330-021-08037-y
- Williamson EE, Kirsch J, Araoz PA, et al. ECG-gated cardiac CT angiography using 64-MDCT for detection of patent foramen ovale. AJR Am J Roentgenol. 2008;190(4):929-933. doi: 10.2214/AJR.07.3140
- Shah AH, Horlick EM, Kass M, Carroll JD, Krasuski RA. The pathophysiology of patent foramen ovale and its related complications. Am Heart J. 2024. doi: 10.1016/j.ahj.2024.08.001
- Yan C, et al. Frequency and size of in situ thrombus within patent foramen ovale. Stroke. 2023;54(5):1205-1213. doi: 10.1161/STROKEAHA.122.041524
- Ren W, Huang H, Hu H. Optical coherence tomography imaging evidence of thrombus inside the tunnel of patent foramen ovale. Eur Heart J. 2022;43(39):3982. doi: 10.1093/eurheartj/ehac465
- Yan C, Li H. Preliminary investigation of in situ thrombus within patent foramen ovale in patients with and without stroke. JAMA. 2021;325(20):2116-2118. doi: 10.1001/jama.2021.4359
- Mackman N. New insights into the mechanisms of venous thrombosis. J Clin Invest. 2012;122(7):2331-2336. doi: 10.1172/JCI60229
- Parikh JD, et al. 4D flow MRI assessment of right atrial flow patterns in the normal heart: influence of caval vein arrangement and implications for patent foramen ovale. PLoS One. 2017;12(3):e0173046. doi: 10.1371/journal.pone.0173046
- Shah AH, Osten MD, Leventhal A, et al. Percutaneous intervention to treat platypnea-orthodeoxia syndrome: the Toronto experience. JACC Cardiovasc Interv. 2016;9(18):1928-1938. doi: 10.1016/j.jcin.2016.07.003
- Shah AH, Ravandi A, Kass M. Platypnea-orthodeoxia syndrome: reminder of the in utero vena cava flow pattern. JACC Cardiovasc Interv. 2019;12(2):e15-e16. doi: 10.1016/j.jcin.2018.10.040
- Foerch C, Misselwitz B, Sitzer M, Berger K, Steinmetz H, Neumann-Haefelin T. Difference in recognition of right and left hemispheric stroke. Lancet. 2005;366(9483):392-393. doi: 10.1016/S0140-6736(05)67024-9
- Carr IA, Nemoto N, Schwartz RS, Shadden SC. Size-dependent predilections of cardiogenic embolic transport. Am J Physiol Heart Circ Physiol. 2013;305(5):H732-H739. doi: 10.1152/ajpheart.00320.2013
- Chung EML, Hague JP, Chanrion MA, Ramnarine KV, Katsogridakis E, Evans DH. Embolus trajectory through a physical replica of the major cerebral arteries. Stroke. 2010;41(4):647-652. doi: 10.1161/STROKEAHA.109.574400
- Hedna VS, et al. Hemispheric differences in ischemic stroke: is left-hemisphere stroke more common? J Clin Neurol. 2013;9(2):97-102. doi: 10.3988/JCN.2013.9.2.97
- Brott T, et al. Baseline silent cerebral infarction in the asymptomatic carotid atherosclerosis study. Stroke. 1994;25(6):1122-1129. doi: 10.1161/01.STR.25.6.1122
- Badea RS, et al. PFO-spectrum disorder: two different cerebrovascular diseases in patients with PFO as detected by AI brain imaging software. Front Neurol. 2024;15:1357348. doi: 10.3389/fneur.2024.1357348
- Clergeau MR, Hameon M, Morello R, Saloux E, Viader F, Hamon M. Silent cerebral infarcts in patients with pulmonary embolism and a patent foramen ovale: a prospective diffusion weighted MRI study. Stroke. 2009;40(12):3758-3762. doi: 10.1161/STROKEAHA.109.559898
- Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-3826. doi: 10.1093/eurheartj/ehad191
- Shibata T, Kawakami S, Noguchi T, et al. Prevalence, clinical features, and prognosis of acute myocardial infarction attributable to coronary artery embolism. Circulation. 2015;132(4):241-250. doi: 10.1161/CIRCULATIONAHA.114.015134
- Ferrari MD, Klever RR, Terwindt GM, et al. Migraine pathophysiology: lessons from mouse models and human genetics. Lancet Neurol. 2015;14(1):65-80. doi: 10.1016/S1474-4422(14)70220-0
- Charles A. The pathophysiology of migraine: implications for clinical management. Lancet Neurol. 2018;17(2):174-182. doi: 10.1016/S1474-4422(17)30435-0
- Goadsby PJ, Holland PR, Martins-Oliveira M, et al. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97(2):553-622. doi: 10.1152/physrev.00034.2015
- Lipton RB, Bigal ME, Diamond M, et al. Migraine prevalence, disease burden, and the need for preventive therapy. Neurology. 2007;68(5):343-349. doi: 10.1212/01. WNL.0000252808.97649.21
- Azarbal B, Tobis J, Suh W, et al. Association of interatrial shunts and migraine headaches: impact of transcatheter closure. J Am Coll Cardiol. 2005;45(4):489-492. doi: 10.1016/j.jacc.2004.09.075
- Caputi L, Carriero MR, Falcone C, et al. Microembolic air load during contrast-transcranial Doppler: a trigger for migraine with aura? Headache. 2010;50(8):1320-1327. doi: 10.1111/j.1526-4610.2010.01621.x
- Sarvananthan T, Shepherd AC, Willenberg T, Davies AH. Neurological complications of sclerotherapy for varicose veins. J Vasc Surg. 2012;55(1):243-251. doi: 10.1016/j.jvs.2011.05.093
- Said SI. Metabolic functions of the pulmonary circulation. Circ Res. 1982;50(3):325-333. doi: 10.1161/01.RES.50.3.325
- Yan C, Li H, Chen Y, et al. Frequency and size of in situ thrombus within patent foramen ovale. Stroke. 2023;54(5):1205-1213. doi: 10.1161/STROKEAHA.122.041524
- Ren W, Huang H, Hu H. Optical coherence tomography imaging evidence of thrombus inside the tunnel of patent foramen ovale. Eur Heart J. 2022;43(39):3982. doi: 10.1093/eurheartj/ehac465
- Lantz M, Sieurin J, Sjölander A, et al. Migraine and risk of stroke: a national population-based twin study. Brain. 2017;140(10):2653-2662. doi: 10.1093/brain/awx223
- Schwerzmann M, Nedeltchev K, Lagger F, et al. Percutaneous closure of patent foramen ovale reduces the frequency of migraine attacks. Neurology. 2004;62(8):1399-1401. doi: 10.1212/01.WNL.0000120677.64217.A9
- Mojadidi MK, Gevorgyan R, Noureddin N, et al. Pooled analysis of PFO occluder device trials in patients with PFO and migraine. J Am Coll Cardiol. 2021;77(6):667-676. doi: 10.1016/j.jacc.2020.11.068
- Rodés-Cabau J, et al. Incidence, timing, and predictive factors of new-onset migraine headache after transcatheter closure of atrial septal defect or patent foramen ovale. Am J Cardiol. 2008;101(5):688-692. doi: 10.1016/j.amjcard.2007.10.034
- Rodés-Cabau J, et al. Effect of clopidogrel and aspirin vs aspirin alone on migraine headaches after transcatheter atrial septal defect closure: the CANOA randomized clinical trial. JAMA. 2015;314(20):2147-2154. doi: 10.1001/jama.2015.13919
- Dowson A, et al. Migraine intervention with STARFlex technology (MIST) trial. Circulation. 2008;117(11):1397-1404. doi: 10.1161/CIRCULATIONAHA.107.727271
- Tobis JM, Abudayyeh I. Platypnea-orthodeoxia syndrome: an overlooked cause of hypoxemia. JACC Cardiovasc Interv. 2016;9(18):1939-1940. doi: 10.1016/j.jcin.2016.08.002
- Henkin S, Negrotto S, Pollak PM, et al. Platypnea-orthodeoxia syndrome: case reports. Tex Heart Inst J. 2015;42(5):498-501. doi: 10.14503/THIJ-14-4596
- Henkin S, Negrotto S, Pollak PM, et al. Platypnea-orthodeoxia syndrome: diagnostic challenge and the importance of heightened clinical suspicion. Tex Heart Inst J. 2015;42(5):498-501. doi: 10.14503/THIJ-14-4596
- Caso V, et al. European Stroke Organisation (ESO) guidelines on the diagnosis and management of patent foramen ovale after stroke. Eur Stroke J. 2024;9(4):800-834. doi: 10.1177/23969873241247978
- Cotter PE, Martin PJ, Ring L, et al. Incidence of atrial fibrillation detected by implantable loop recorders in unexplained stroke. Neurology. 2013;80(17):1546-1550. doi: 10.1212/WNL.0b013e31828f1828
- Sanna T, Diener HC, Passman RS, et al. Cryptogenic stroke and underlying atrial fibrillation. N Engl J Med. 2014;370(26):2478-2486. doi: 10.1056/NEJMoa1313600
- Christensen LM, et al. Paroxysmal atrial fibrillation occurs often in cryptogenic ischaemic stroke: final results from the SURPRISE study. Eur J Neurol. 2014;21(6):884-889. doi: 10.1111/ene.12400
- Mir H, et al. Patent foramen ovale closure, antiplatelet therapy or anticoagulation in patients with PFO and cryptogenic stroke: systematic review and network meta-analysis. BMJ Open. 2018;8(7):e023761. doi: 10.1136/bmjopen-2018-023761
- Kent DM, et al. An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke. Neurology. 2013;81(7):619-625. doi: 10.1212/WNL.0b013e3182a08d59
- Kim JS. Patent foramen ovale and other cardiopathies as causes of embolic stroke with unknown source. J Stroke. 2024;26(3):349-359. doi: 10.5853/jos.2024.02670
- Krumsdorf U, et al. Incidence and clinical course of thrombus formation on atrial septal defect and patent foramen ovale closure devices in 1,000 consecutive patients. J Am Coll Cardiol. 2004;43(2):302-309. doi: 10.1016/j.jacc.2003.10.030
- Alqahtani F, et al. Intracardiac versus transesophageal echocardiography to guide transcatheter closure of interatrial communications. J Interv Cardiol. 2017;30(3):234-242. doi: 10.1111/joic.12382
- Devos P, Guedeney P, Montalescot G. Patent foramen ovale percutaneous closure: evolution and ongoing challenges. J Clin Med. 2023;13(1):54. doi: 10.3390/jcm13010054
- Kavinsky CJ, et al. SCAI guidelines for the management of patent foramen ovale. J Soc Cardiovasc Angiogr Interv. 2022;1(4):100039. doi: 10.1016/j.jscai.2022.100039
- Søndergaard L, et al. Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke. N Engl J Med. 2017;377(11):1033-1042. doi: 10.1056/NEJMoa1707404
- Kefer J, et al. Antithrombotic therapy duration after patent foramen ovale closure for stroke prevention: impact on longterm outcome. J Interv Cardiol. 2022;2022:6559447. doi: 10.1155/2022/6559447
- Dia AR, Cifu AS, Shah AP. Management of patients with a patent foramen ovale with history of stroke or TIA. JAMA. 2021;325(1):81-82. doi: 10.1001/jama.2020.22176
- Berdat PA, Chatterjee T, Pfammatter JP, et al. Surgical management of complications after transcatheter closure of an atrial septal defect or patent foramen ovale. J Thorac Cardiovasc Surg. 2000;120(6):1034-1039. doi: 10.1067/mtc.2000.111054
- Merkler AE, et al. Safety outcomes after percutaneous transcatheter closure of patent foramen ovale. Stroke. 2017;48(11):3073-3077. doi: 10.1161/STROKEAHA.117.018501
- Elgendy AY, et al. New-onset atrial fibrillation following percutaneous patent foramen ovale closure: systematic review and meta-analysis. EuroIntervention. 2019;14(17):1788-1790. doi: 10.4244/EIJ-D-18-00767
- Guedeney P, et al. Supraventricular arrhythmia following patent foramen ovale percutaneous closure. JACC Cardiovasc Interv. 2022;15(22):2315-2322. doi: 10.1016/j.jcin.2022.07.044
- Goel SS, Aksoy O, Tuzcu EM, et al. Embolization of patent foramen ovale closure devices: incidence and management. Tex Heart Inst J. 2013;40(4):439-444.
- Mas JL, et al. Patent foramen ovale closure or anticoagulation vs antiplatelets after stroke. N Engl J Med. 2017;377(11):1011-1021. doi: 10.1056/NEJMoa1705915
- Saver JL, et al. Long-term outcomes of patent foramen ovale closure or medical therapy after stroke. N Engl J Med. 2017;377(11):1022-1032. doi: 10.1056/NEJMoa1610057
- Reddy BT, Patel JB, Powell DL, Michaels AD. Interatrial shunt closure devices in patients with nickel allergy. Catheter Cardiovasc Interv. 2009;74(4):647-651. doi: 10.1002/ccd.22155
- Rabkin DG, Whitehead KJ, Michaels AD, et al. Unusual presentation of nickel allergy requiring explantation of an Amplatzer atrial septal occluder device. Clin Cardiol. 2009;32(8):E55-E57. doi: 10.1002/clc.20427