TABLE 1.
Preoperative demographic characteristics
| Variable | Patients with CTD (n = 18) | Patients without CTD (n = 98) |
|---|---|---|
| Age at the time of surgery, mean ± s.d. (years) | 52 ± 20 | 52 ± 22 |
| Male, n (%) | 7 (39%) | 70 (71%) |
| Female, n (%) | 11 (61%) | 28 (29%) |
| Obesity (BMI > 30 kg/m2), n (%) | 2 (11%) | 25 (25%) |
| Hypertension, n (%) | 14 (78%) | 84 (86%) |
| Diabetes mellitus, n (%) | 1 (5%) | 7 (7%) |
| Atherosclerosis, n (%) | 3 (16%) | 20 (20%) |
| Stroke/neurological disorder, n (%) | 3 (16%) | 25 (25%) |
| Renal failure, n (%) | 0 (0%) | 11 (11%) |
| Atrial fibrillation, n (%) | 5 (28%) | 40 (41%) |
| Immunosuppression, n (%) | 1 (5%) | 4 (4%) |
| Aortic valve disease | ||
| Aortic regurgitation, n (%) | 17 (94%) | 72 (73%) |
| Aortic stenosis, n (%) | 0 | 8 (8%) |
| Mixed aortic valve disease, n (%) | 0 | 3 (3%) |
| No aortic valve disease, n (%) | 1 (5%) | 16 (16%) |
TABLE 2.
Peri- and postprocedural characteristics of primary surgery before TAFA development
| Variable | Patients with CTD (n = 18) | Patients without CTD (n = 98) |
|---|---|---|
| Duration of cardiopulmonary bypass, min, mean ± s.d. | 174 ± 56 | 182 ± 72 |
| Cross-clamp time, min, mean ± s.d. | 112 ± 32 | 112 ± 35 |
| Duration of circulatory arrest, min, mean ± s.d. | 16 ± 27 | 20 ± 28 |
| Proximal suture with PTFE circumferential felt strip, n (%) | 2 (11%) | 36 (37%) |
| Distal suture with PTFE circumferential felt strip, n (%) | 7 (39%) | 49 (50%) |
| Use of biological glue, n (%) | 18 (100%) | 94 (96%) |
| Surgical re-exploration, n (%) | 2 (11%) | 25 (25%) |
| Wound infection, n (%) | 0 (0%) | 9 (9%) |
| Multiple surgeries until TAFA development, n (%) | 4 (22%) | 8 (8%) |
| Antiplatelet therapy after surgery, n (%) | 1 (5%) | 26 (26%) |
| Anticoagulation after surgery, n (%) | 17 (94%) | 59 (60%) |

FIGURE 1.
CT scan of aortic pseudoaneurysm.

FIGURE 2.
Kaplan–Meier analysis of survival of patients with TAFA (with CTD vs. without CTD)

FIGURE 3.
Kaplan–Meier analysis of survival of patients with TAFA and CTD (aortic aneurysm, dissection)

FIGURE 4.
Kaplan–Meier analysis of survival of patients with TAFA and without CTD (aortic aneurysm, dissection)