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Metoprolol Use in Hypertensive Pregnancy Disorder – a Single-center Study Cover

Metoprolol Use in Hypertensive Pregnancy Disorder – a Single-center Study

Open Access
|Mar 2025

References

  1. Verma V, Parashar S, Lata K, Gaur P, Kaushik R, Sharma V. Pattern of treatment approaches for preeclampsia during pregnancy. Journal of Applied Pharmaceutical Sciences and Research. 2024;7(2):10–14. doi: 10.31069/japsr.v7i2.02
  2. Mitranovici MI, Chiorean DM, Moraru R, et al. Understanding the Pathophysiology of Preeclampsia: Exploring the Role of Antiphospholipid Antibodies and Future Directions. J Clin Med. 2024 May 2;13(9):2668. doi: 10.3390/jcm13092668
  3. Mitranovici MI, Chiorean DM, Oală IE, Petre I, Cotoi OS. Evaluation of the Obstetric Patient: Pregnancy Outcomes during COVID-19 Pandemic—A Single-Center Retrospective Study in Romania. Reports. 2022;5(3):27. doi: 10.3390/reports5030027
  4. Khan DSA, Hamid LR, Ali A, Salam RA, Zuberi N, Lassi ZS, Das JK. Differences in pregnancy and perinatal outcomes among symptomatic versus asymptomatic COVID-19-infected pregnant women: a systematic review and meta-analysis. BMC Pregnancy Childbirth. 2021 Dec 1;21(1):801. doi: 10.1186/s12884-021-04250-1
  5. Garovic VD, Dechend R, Easterling T, et al; American Heart Association Council on Hypertension; Council on the Kidney in Cardiovascular Disease, Kidney in Heart Disease Science Committee; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Lifestyle and Cardiometabolic Health; Council on Peripheral Vascular Disease; and Stroke Council. Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals, and Pharmacotherapy: A Scientific Statement From the American Heart Association. Hypertension. 2022 Feb;79(2):e21–e41. doi: 10.1161/HYP.0000000000000208
  6. Binder NK, MacDonald TM, Beard SA, et al. Pre-Clinical Investigation of Cardioprotective Beta-Blockers as a Therapeutic Strategy for Preeclampsia. J Clin Med. 2021 Jul 30;10(15):3384. doi: 10.3390/jcm10153384.
  7. Anand S. Antihypertensive in Pregnancy-Pharmacotherapy Options. Biomedical and Pharmacology Journal. 2015;7(1):289–294. doi: 10.13005/bpj/490
  8. Sinkey RG, Battarbee AN, Bello NA, Ives CW, Oparil S, Tita ATN. Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines. Curr Hypertens Rep. 2020 Aug 27;22(9):66. doi: 10.1007/s11906-020-01082-w
  9. Mitranovici MI, Pușcașiu L, Oală IE, et al. A Race against the Clock: A Case Report and Literature Review Concerning the Importance of ADAMTS13 Testing in Diagnosis and Management of Thrombotic Thrombocytopenic Purpura during Pregnancy. Diagnostics (Basel). 2022 Jun 27;12(7):1559. doi: 10.3390/diagnostics12071559
  10. Leonard SA, Siadat S, Main EK, et al. Chronic Hypertension During Pregnancy: Prevalence and Treatment in the United States, 2008–2021. Hypertension. 2024 Aug;81(8):1716–1723. doi: 10.1161/HYPERTENSIONAHA.124.22731
  11. Yakoob MY, Bateman BT, Ho E, et al. The risk of congenital malformations associated with exposure to β-blockers early in pregnancy: a meta-analysis. Hypertension. 2013 Aug;62(2):375–381. doi: 10.1161/HYPERTENSIONAHA.111.00833
  12. Bozdağ H, Öğütcüoğlu FB, Duran EA, et al. The frequency and fetomaternal outcomes of early-and late-onset preeclampsia: The experience of a single tertiary health center in the bustling metropolis of Turkey; Istanbul. Medeniyet Medical Journal. 2015;30(4):163–169. doi: 10.5222/MMJ.2015.163
  13. Gryglas P, Jedrusik P, Wojciechowska E, et al. [PP.24.01] Serial ambulatory blood pressure monitoring, intensity of antihypertensive drug treatment, and pregnancy outcomes in women with hypertension found early during pregnancy. Journal of Hypertension. 2016;34:p e261. doi: 10.1097/01.hjh.0000492094.66024.ce
  14. Das SR, Bhusanpanigrahi B, Pani MK. Metoprolol succinate as selective drugs for treatment of hypertension in pregnancyas bi layer floating tablet: a review. International Journal of Pharmaceutical Research. 2019;11(4):673. doi: 10.31838/ijpr/2019.11.04.025
  15. Ghafarzadeh M, Shakarami A, Yari F, Namdari P. The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. Hypertens Pregnancy. 2020 Aug;39(3):314–318. doi: 10.1080/10641955.2020.1766489
  16. Redman CW. Controlled trials of antihypertensive drugs in pregnancy. Am J Kidney Dis. 1991 Feb;17(2):149–53. doi: 10.1016/s0272-6386(12)81120-6
  17. Kubota K, Inai K, Shimada E, Shinohara T. α/β- and β-Blocker Exposure in Pregnancy and the Risk of Neonatal Hypoglycemia and Small for Gestational Age. Circ J. 2023 Mar 24;87(4):569–577. doi: 10.1253/circj.CJ-22-0647
  18. Akgün Aktaş B, Uzuner PF, Tanacan A, Sahin D. Obstetrics and fetal outcomes in pregnant women with beta-blocker treatment in maternal arrhythmia. JGON. 2024;21(1):8–12. doi: 10.38136/jgon.1275121
  19. Kayser A, Beck E, Hoeltzenbein M, et al. Neonatal effects of intrauterine metoprolol/bisoprolol exposure during the second and third trimester: a cohort study with two comparison groups. J Hypertens. 2020 Feb;38(2):354–361. doi: 10.1097/HJH.0000000000002256
  20. Sandström B. Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy. Gynecol Invest. 1978;9(4):195–204. doi: 10.1159/000300984
  21. Katsi V, Papakonstantinou IP, Papazachou O, Makris T, Tsioufis K. Beta-Blockers in Pregnancy: Clinical Update. Curr Hypertens Rep. 2023 Feb;25(2):13–24. doi: 10.1007/s11906-023-01234-8
  22. Wang Y, Liu C, He X, Li Y, Zou Y. Effects of metoprolol, methyldopa, and nifedipine on endothelial progenitor cells in patients with gestational hypertension and preeclampsia. Clin Exp Pharmacol Physiol. 2019 Apr;46(4):302–312. doi: 10.1111/1440-1681.13063
  23. Vázquez-Rodríguez JG, Sánchez-Pardo CI. Postpartum Arterial Hypertension Management in Patients with Severe Preeclampsia. The Experience of a High Specialty Hospital of Mexico City. Journal of Advances in Medicine and Medical Research. 2022;34(23):111–121. doi: 10.9734/jammr/2022/v34i234844
  24. Miller J, Mishra S, Jena S, et al. Pregnancy induced hypertension & pre eclampsia: Pathophysiology & recent management trends: A review. IJPRAS. 2016;5(3):326–334.
  25. Pankiewicz K, Szczerba E, Fijałkowska A, Sierdziński J, Issat T, Maciejewski TM. The Impact of Coexisting Gestational Diabetes Mellitus on the Course of Preeclampsia. J Clin Med. 2022 Oct 28;11(21):6390. doi: 10.3390/jcm11216390
  26. Haas DM. Pharmacogenetics and individualizing drug treatment during pregnancy. Pharmacogenomics. 2014 Jan;15(1):69–78. doi: 10.2217/pgs.13.228
  27. Iannaccone A, Reisch B, Kimmig R, et al. Therapeutic Plasma Exchange in Early-Onset Preeclampsia: A 7-Year Monocentric Experience. J Clin Med. 2023 Jun 26;12(13):4289. doi: 10.3390/jcm12134289
  28. Attar A, Hosseinpour A, Moghadami M. The impact of antihypertensive treatment of mild to moderate hypertension during pregnancy on maternal and neonatal outcomes: An updated meta-analysis of randomized controlled trials. Clin Cardiol. 2023 May;46(5):467–476. doi: 10.1002/clc.24013
  29. Cox AG, Marshall SA, Palmer KR, Wallace EM. Current and emerging pharmacotherapy for emergency management of preeclampsia. Expert Opin Pharmacother. 2019 Apr;20(6):701–712. doi: 10.1080/14656566.2019.1570134
  30. Cavallasca JA, Costa CA, Maliandi MDR, Musuruana JL. Hot topics in lupus pregnancy. World J Rheumatol. 2013;3(3):32–39. doi: 10.5499/wjr.v3.i3.32
  31. Mitranovici M-I, Chiorean DM, Mureșan MC, et al. Treating Preeclampsia in the COVID-19 Era: Is Allopurinol Useful as an Adjuvant Therapy? A Case Report and Review of the Literature. Stresses. 2023;3(1):125–135. doi : 10.3390/stresses3010010
  32. Editors. Hypertension Editors' Picks: Preeclampsia, Pregnancy, and Hypertension. Hypertension. 2018 Jul;72(1):e1–e18. doi: 10.1161/HYPERTENSIONAHA.118.11037
  33. Saleh L, Verdonk K, Jan Danser AH, et al. The sFlt-1/PlGF ratio associates with prolongation and adverse outcome of pregnancy in women with (suspected) preeclampsia: analysis of a high-risk cohort. Eur J Obstet Gynecol Reprod Biol. 2016 Apr;199:121–6. doi: 10.1016/j.ejogrb.2016.02.013
  34. Chiorean DM, Cobankent Aytekin E, Mitranovici MI, et al. Human Placenta and Evolving Insights into Pathological Changes of Preeclampsia: A Comprehensive Review of the Last Decade. Fetal Pediatr Pathol. 2024 Jan–Feb;43(1):33–46. doi: 10.1080/15513815.2023.2274823
  35. Wang X, Guan M, Zhang X, et al. The Association Between S100A8/A9 and the Development of Very Late Stent Thrombosis in Patients With Acute Myocardial Infarction. Clin Appl Thromb Hemost. 2020;26:1076029620943295. doi: 10.1177/1076029620943295
DOI: https://doi.org/10.2478/jce-2025-0001 | Journal eISSN: 2457-5518 | Journal ISSN: 2457-550X
Language: English
Page range: 20 - 25
Submitted on: Dec 3, 2024
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Accepted on: Jan 8, 2025
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Published on: Mar 28, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Corneliu-Florin Buicu, Melinda-Ildiko Mitranovici, Septimiu Voidazan, Marius Craina, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution 3.0 License.