General characteristics and findings of the studies included in the analysis
| Study | Disease | Year | No. of patients | Mean age (years) | Male sex (%) | Outcome |
|---|---|---|---|---|---|---|
| Nihat et al.17 | Unstable angina pectoris/NSTEMI | 2020 | 403 | 64 ± 12 | 60.0 | Patients with unstable angina pectoris or NSTEMI and hypoalbuminemia are more likely to die over the long term than those without hypoalbuminemia. |
| Chien et al.19 | Coronary heart disease | 2017 | 734 | 62.1 ± 12.4 | 84.1 | Reduced serum albumin concentration (<3.5 g/dl) impairs patients’ chances of having stable congestive heart failure. |
| Ancion et al.20 | Acute non-ischemic heart failure | 2017 | 546 | 72 ± 12 | 59.0 | Serum albumin level is a simple predictive factor in non-ischemic heart failure. |
| Northern Manhattan Study29 | Incident stroke | 2014 | 2,986 | 69 ± 10 | 37.2 | There is a relationship between low serum albumin levels and stroke. |
| González-Pacheco et al.39 | Acute coronary syndrome | 2017 | 8,848 | 62 ± 13 | 74.9 | A serum albumin level <3.5 g/dl is an independent predictor of newly-diagnosed heart failure in patients with acute coronary syndrome. |
| Kempny et al.40 | Adult congenital heart disease | 2015 | 2,886 | 33.3 ± 12.9 | 50.1 | Hypoalbuminemia is a robust, independent predictor of mortality in patients with adult congenital heart disease. |
| Bhamidipati et al.41 | Coronary artery bypass grafting | 2011 | 2,794 | 64.6 ± 12.9 | 30.1 | In isolated coronary artery bypass grafting recipients, albumin is more closely linked to mortality and morbidity than the body mass index. |