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Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review Cover

Serum Albumin Concentration and the Risk of Cardiovascular Disease and Acute Coronary Syndrome — a Narrative Review

Open Access
|Mar 2025

Abstract

Cardiovascular diseases are the primary cause of global health decline. Conditions that cause inflammation and excessive oxidation are present in the early development of the majority of cardiovascular diseases, including coronary artery disease and heart failure. Among the many physiological functions of albumin, its antioxidant, anti-inflammatory, anticoagulant, and antiaggregant properties are the most important. Low serum albumin levels are associated with the occurrence of various cardiovascular diseases such as coronary artery disease, stroke, heart failure, and atrial fibrillation. Several recent meta-analyses support the idea that hypoalbuminemia may act as a modifiable risk factor that increases oxidative stress and inflammation, contributing to the development and progression of cardiovascular diseases. However, it is unclear whether correcting hypoalbuminemia can improve outcomes for patients with cardiovascular diseases and reduce mortality rates. In this regard, further research is crucial.

DOI: https://doi.org/10.2478/jce-2024-0024 | Journal eISSN: 2457-5518 | Journal ISSN: 2457-550X
Language: English
Page range: 11 - 19
Submitted on: Aug 27, 2024
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Accepted on: Sep 20, 2024
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Published on: Mar 28, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Maria Czinege, Florina Ruța, Victoria Nyulas, Vasile-Bogdan Halațiu, Tiberiu Nyulas, Theodora Benedek, published by Asociatia Transilvana de Terapie Transvasculara si Transplant KARDIOMED
This work is licensed under the Creative Commons Attribution 3.0 License.