FIGURE 1.
FIGURE 2.
FIGURE 3.
FIGURE 4.
FIGURE 5.
FIGURE 6.
Pro-atherogenic and prothrombotic mechanisms of Lp(a)4
| Study population (n = 92) | Group 1 – LP (n = 46) | Group 2 – HP (n = 46) | p value | |
|---|---|---|---|---|
| Baseline characteristics of the study groups | ||||
| Age, years (mean ± s.d.) | 61.34 ± 10.72 | 61.38 ± 10.29 | 61.30 ± 11.27 | 0.92 |
| Male sex, n (%) | 67 (72.82%) | 37 (40.22 %) | 30 (32.61 %) | 0.04 |
| Weight (kg, mean ± s.d.) | 83.00 ± 20.99 | 83.84 ± 19.22 | 82.21 ± 22.77 | 0.71 |
| Height (m, mean ± s.d.) | 1.70 ± 0,07 | 1.71 ± 0.08 | 1.69 ± 0.07 | 0.38 |
| BMI (kg/m2, mean ± s.d.) | 28.02 ± 6.92 | 28.35 ± 4.81 | 28.47 ± 7.18 | 0.75 |
| ACS type | ||||
| STEMI, n (%) | 63 (68.47%) | 27 (29.35 %) | 36 (39.13 %) | 0.04 |
| NSTEMI, n (%) | 29 (31.52 %) | 19 (20.65 %) | 10 (10.87 %) | |
| Cardiovascular risk factors/comorbidities | ||||
| Obesity, n (%) | 23 (25.00%) | 11 (12.22 %) | 12 (12.22 %) | >0.99 |
| Recurrent ACS, n (%) | 9 (18.75%) | 4 (4.44 %) | 5 (5.56 %) | >0.99 |
| Heart failure, n (%) | 27 (29.34 %) | 7 (7.87%) | 20 (22.47 %) | 0.002 |
| Dyslipidemia, n (%) | 54 (58.69 %) | 30 (33.33 %) | 24 (26.67 %) | 0.13 |
| Smoker status, n (%) | 41 (50.00 %) | 21 (22.83 %) | 20 (21.72 %) | >0.99 |
| Chronic renal disease, n (%) | 7 (7.60 %) | 3 (3.26 %) | 4 (4.35 %) | >0.99 |
| Diabetes mellitus, n (%) | 19 (20.65 %) | 8 (8.70 %) | 11 (11.96 %) | 0.60 |
| Hypertension, n (%) | 69 (75.00%) | 35 (77.78 %) | 34 (72.34 %) | 0.63 |
| Atrial fibrillation, n (%) | 27 (29.34%) | 7 (7.78%) | 20 (22.22%) | 0.005 |
| Culprit lesion | ||||
| Left anterior descending artery, n (%) | 68 (73.91 %) | 33 (36.67 %) | 35 (38.89 %) | >0.99 |
| Circumflex artery, n (%) | 50 (54.34 %) | 27 (30.00 %) | 23 (25.56 %) | 0.29 |
| Right coronary artery, n (%) | 53 (57.60 %) | 27 (30.00 %) | 26 (28.89 %) | 0.67 |