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Exploring pharmacological strategies in the management of ARDS: Efficacy, limitations, and future directions Cover

Exploring pharmacological strategies in the management of ARDS: Efficacy, limitations, and future directions

Open Access
|Jul 2025

Abstract

Acute respiratory distress syndrome (ARDS) is a severe inflammatory reaction in the lungs caused by sudden pulmonary and systemic injuries. Clinically, this diverse syndrome is marked by sudden hypoxemic respiratory failure and the presence of bilateral lung infiltrates visible on a chest X-ray. ARDS management remains largely supportive, with a focus on optimizing mechanical ventilation strategies and addressing the underlying causes of lung injury. The current pharmacological approach for ARDS primarily focuses on corticosteroids, neuromuscular blocking agents, and beta-2 agonists, however, none has been definitively proven to be consistently effective in improving clinical outcomes. This review summarizes the latest evidence regarding the effectiveness and limitations of these pharmacological interventions, identifying key areas where further research is needed.

DOI: https://doi.org/10.2478/jccm-2025-0030 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 208 - 220
Submitted on: Feb 5, 2025
Accepted on: Jul 3, 2025
Published on: Jul 31, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Sultan Almuntashiri, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.