Have a personal or library account? Click to login
Hyperglycemia, diabetes, and de novo diabetes in patients hospitalized in intensive care units for COVID-19 in Colombia: Results from a longitudinal cohort study Cover

Hyperglycemia, diabetes, and de novo diabetes in patients hospitalized in intensive care units for COVID-19 in Colombia: Results from a longitudinal cohort study

Open Access
|Jul 2025

References

  1. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–42.
  2. Docherty AB, Harrison EM, Green CA, Hardwick HE, Pius R, Norman L, et al. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterization Protocol: prospective observational cohort study. BMJ. 2020;369:m1985.
  3. Al-Kuraishy HM, Al-Gareeb AI, Alblihed M, Guerreiro SG, Cruz-Martins N, Batiha GE. COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus. Front Cardiovasc Med. 2021;8:644095
  4. Yang JK, Lin SS, Ji XJ, Guo LM. Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol. 2010;47(3):193–9.
  5. Kazakou P, Lambadiari V, Ikonomidis I, Kountouri A, Panagopoulos G, Athanasopoulos S, et al. Diabetes and COVID-19; A Bidirectional Interplay. Front Endocrinol (Lausanne). 2022;13:780663.
  6. Knebusch Toriello N, Prato Alterio NM, Ramírez Villeda LM. Newly Diagnosed Diabetes Mellitus During COVID-19: The New Pandemic - A Literature Review. Curr Trop Med Rep. 2022;9(4):250–256.
  7. Hirani D, Salem V, Khunti K, Misra S. Newly detected diabetes during the COVID-19 pandemic: What have we learnt? Best Pract Res Clin Endocrinol Metab. 2023;37(4):101793.
  8. de Sá-Ferreira CO, da Costa CHM, Guimarães JCW, Sampaio NS, Silva LML, de Mascarenhas LP, Rodrigues NG, Dos Santos TL, Campos S, Young EC. Diabetic ketoacidosis and COVID-19: what have we learned so far? Am J Physiol Endocrinol Metab. 2022;322(1):E44–E53
  9. Chandrashekhar Joshi S, Pozzilli P. COVID-19 induced Diabetes: A novel presentation. Diabetes Res Clin Pract. 2022;191:110034.
  10. Pantea Stoian A, Bica IC, Salmen T, Al Mahmeed W, Al-Rasadi K, Al-Alawi K et al; Cardiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO). New-Onset Diabetes Mellitus in COVID-19: A Scoping Review. Diabetes Ther. 2023.
  11. Pantea Stoian A, Pricop-Jeckstadt M, Pana A, Ileanu BV, Schitea R, Geanta M, Catrinoiu D, Suceveanu AI, Serafinceanu C, Pituru S, Poiana C, Timar B, Nitipir C, Parvu S, Arsene A, Mazilu L, Toma A, Hainarosie R, Ceriello A, Rizzo M, Jinga V. Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study. Sci Rep. 2020;10(1):21613.
  12. Singh AK, Singh R. Hyperglycemia without diabetes and new-onset diabetes are both associated with poorer outcomes in COVID-19. Diabetes Res Clin Pract. 2020 Sep;167:108382.
  13. American Diabetes Association. 16. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2022. Diabetes Care. 2021 16;45(Supplement_1):S244–53.
  14. Hobohm L, Sagoschen I, Barco S, Schmidtmann I, Espinola-Klein C, Konstantinides S, Münzel T, Keller K. Trends and Risk Factors of In-Hospital Mortality of Patients with COVID-19 in Germany: Results of a Large Nationwide Inpatient Sample. Viruses. 2022;14(2):275.
  15. Schmitt VH, Hobohm L, Sagoschen I, Sivanathan V, Hahad O, Espinola-Klein C, Münzel T, Keller K. Diabetes Mellitus and Its Association with Adverse In-Hospital Outcomes in Patients with COVID-19-A Nationwide Study. Viruses. 2023;15(8):1627.
  16. Xiao F, Zhou YC, Zhang MB, Chen D, Peng SL, Tang HN, Li L, Tang CY, Liu JY, Li B, Zhou HD. Hyperglycemia and blood glucose deterioration are risk factors for severe COVID-19 with diabetes: A two-center cohort study. J Med Virol. 2022;94(5):1967–1975.
  17. Chang MC, Hwang JM, Jeon JH, Kwak SG, Park D, Moon JS. Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study. Endocrinol Metab (Seoul). 2020;35(3):595–601.
  18. Liu Z, Bai X, Han X, Jiang W, Qiu L, Chen S, Yu X. The association of diabetes and the prognosis of COVID-19 patients: A retrospective study. Diabetes Res Clin Pract. 2020;169:108386
  19. Greco C, Pirotti T, Brigante G, Filippini T, Pacchioni C, Trenti T, Simoni M, Santi D. Glycemic control predicts SARS-CoV-2 prognosis in diabetic subjects. Acta Diabetol. 2023;60(6):817–825
  20. Liu L, Wei W, Yang K, Li S, Yu X, Dong C, Zhang B. Glycemic control before admission is an important determinant of prognosis in patients with coronavirus disease 2019. J Diabetes Investig. 2021;12(6):1064–1073.
  21. Xie Y, Al-Aly Z. Risks and burdens of incident diabetes in long COVID: a cohort study. Lancet Diabetes Endocrinol. 2022;10(5):311–321
  22. Zhang Y, Li H, Zhang J, Cao Y, Zhao X, Yu N, et al. The clinical characteristics and outcomes of patients with diabetes and secondary hyperglycaemia with coronavirus disease 2019: A single-center, retrospective, observational study in Wuhan. Diabetes Obes Metab. 2020;22(8):1443–1454. doi:10.1111/dom.14086.
  23. Li H, Tian S, Chen T, Cui Z, Shi N, Zhong X, et al. Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID-19. Diabetes Obes Metab. 2020;22(10):1897–1906. doi:10.1111/dom.14099.
  24. Fadini GP, Morieri ML, Boscari F, Fioretto P, Maran A, Busetto L, et al. Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration. Diabetes Res Clin Pract. 2020;168:108374. doi:10.1016/j.diabres.2020.108374.
  25. Ssentongo P, Zhang Y, Witmer L, Chinchilli VM, Ba DM. Association of COVID-19 with diabetes: a systematic review and meta-analysis. Sci Rep. 2022;12(1):20191. doi:10.1038/s41598-022-24185-7.
DOI: https://doi.org/10.2478/jccm-2025-0026 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 257 - 264
Submitted on: Jun 10, 2024
Accepted on: Jun 5, 2025
Published on: Jul 31, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 John Jaime Sprockel, Ana Maria Perez, Maria Camila Chamorro, Jose Alejandro Vergel, Ximena Espinosa, Juan Carlos Vargas, Carlos Angarita, Jhon Edinson Parra, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.