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A brief report on the association of preoperative hematological indices and acute deep vein thrombosis following total hip arthroplasty for osteoarthritis Cover

A brief report on the association of preoperative hematological indices and acute deep vein thrombosis following total hip arthroplasty for osteoarthritis

Open Access
|Apr 2025

Figures & Tables

Table 1.

Patient comorbidities and demographic data

All patients (n=199)DVT (n=12)non-DVT (n=187)p
Age (years) (mean±SD)65.56±10.8170.42±9.9965.25±10.810.13
Gender0.18
Male, n (%)104 (52.26)4 (3.85)100 (96.15)
Female, n (%)95 (47.74)8 (8.42)87 (91.58)
BMI (kg/m2)27.35 ± 4.628.08±3.9227.31±4.650.54
SHT, n (%)147 (73.87)8 (66.66)139 (74.33)0.81
CCD, n (%)76 (38.19)4 (33.33)72 (38.50)0.86
AFib, n (%)9 (4.52)1 (8.33)8 (4.27)0.99
Smoker, n (%)6 (3.02)1 (8.33)5 (2.67)0.76
CHF, n (%)11 (5.52)0 (0)11 (5.88)0.99
Dyslipidemia, n (%)8 (4.02)1 (8.33)6 (3.21)0.35
T2DM, n (%)21 (10.55)2 (16.66)19 (10.16)0.74
Obesity, n (%)11 (5.53)3 (25)8 (4.27)0.54
Malignancy, n (%)8 (4.02)0 (0)8 (4.27)0.99
CKD, n (%)2 (1)0 (0)2 (1.07)0.99
Varicose veins, n (%)14 (7.04)1 (8.33)13 (6.95)0.79

[i] BMI, body mass index; SHT, systemic hypertension; CCD, chronic coronary disease; AFib, atrial fibrillation; CHF, congestive heart failure; T2DM, type 2 diabetes mellitus; CKD, chronic kidney disease.

Table 2.

Laboratory parameters of the patients

Parameter median (Q1-Q3)All patients (n=199)DVT (n=12)non-DVT (n=187)p
Hb (g/dL)13.8 (12.83–14.77)13.71 (12.53 – 14.45)13.8 (12.8 – 14.8)0.42
Hct (%)41.7 (39.13–44.4)41.06 (37.23–42.26)41.8 (39.25 – 44.42)0.28
Neu (×103/µL)4.84 (3.7–5.98)4.47 (4.12–6.26)4.85 (3.69–5.98)0.66
Ly (×103/µL)1.97 (1.51–2.55)1.56 (1.09–2.44)1.98 (1.55–2.55)0.18
Mo (×103/µL)0.51 (0.41–0.68)0.47 (0.3–0.64)0.51 (0.41–0.68)0.60
Tr (×103/µL)246 (207.5–291.4)210.1 (178.5–284.25)246.4 (211.55–291.4)0.23
MLR0.27 (0.2–0.37)0.36 (0.22–0.53)0.27 (0.2–0.36)0.12
NLR2.45 (1.79–3.19)3.16 (1.7–5.52)2.42 (1.81–3.13)0.27
PLR124.05 (96.96–164.48)163.39 (114.32–175.73)123.01 (96.96–162.51)0.27
SII572.52 (429.22–846.22)660.26 (489.95–1100.5)568.52 (429.22–823.18)0.33
SIRI65.26 (49.05 – 85.63)67.5 (40.62–94.85)65.26 (49.73–85.31)0.89
AISI290.48 (199.83–480.87)302.35 (182.43–761.33)290.48 (204.22–477.56)0.85
Glycemia (mg/dL)102 (92–115)106.49 (83.5–115.75)102 (92–115)0.81
APTT (seconds)25.85 (23.9–28.13)27.45 (27.05–31)25.8 (23.9–28.1)0.09
INR0.98 (0.93–1.08)1 (0.96–1.06)0.98 (0.93–1.08)0.61
Serum urea (mg/dL)34.8 (28.35–42.9)29 (21.88–38.13)35.3 (28.8–42.9)0.13
Serum Creatinine (mg/dL)0.8 (0.72–0.94)0.93 (0.62–1.03)0.8 (0.73–0.94)0.60
LOS (days)7 (6–10)9 (7.75–11.25)7 (6–10)0.38
Death (number)330<0.001

[i] Hb, haemoglobin; Hct, haematocrit; Neu, neutrophil count; Ly, lymphocyte count; Mo, monocyte count; Tr, thrombocyte counts; MLR, monocyte-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; PLR, platelets-to-lymphocyte ratio; SII, systemic inflammatory index; SIRI, systemic inflammation response index (SIRI); AISI, aggregate index of systemic inflammation; APTT, activated partial thromboplastin time; INR, international normalised ratio; LOS, length of hospital stay;

DOI: https://doi.org/10.2478/jccm-2025-0018 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 192 - 197
Submitted on: Dec 7, 2024
Accepted on: Apr 3, 2025
Published on: Apr 30, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Razvan Marian Melinte, Matei Florin Negrut, Daniel Oltean-Dan, Adrian Dumitru Ivanescu, Tudor-Mihai Magdas, Oana Antal, Adela Hilda Onutu, Marian Andrei Melinte, Robert Bolcas, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.