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The use of intraventricular vancomycin in subacute brain abscess in an adolescent male: A case report Cover

The use of intraventricular vancomycin in subacute brain abscess in an adolescent male: A case report

Open Access
|Apr 2025

Abstract

Introduction

Brain abscess is a serious condition in children, leading to rapid deterioration, and permanent neurological damage associated with significant morbidity and mortality. Current management protocols for brain abscesses focus on intravenous antibiotics and surgical excision and drainage.

Case Presentation

A 12-year-old adolescent male who had headache and photophobia and was diagnosed with multiple brain abscesses and was refractory to conventional medical and neurosurgical intervention. A single dose of 10 mg vancomycin was administered through endo-ventricular drain, resulting in resolution of abscesses and alleviation of symptoms.

Conclusion

We describe the first instance of intraventricular vancomycin use in the pediatric age group for the treatment of multiple brain abscesses. Given the variability in dosing reported in the literature, our case report warrants further studies to standardize dosage for this rare intervention.

DOI: https://doi.org/10.2478/jccm-2024-0046 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 198 - 201
Submitted on: Nov 1, 2024
Accepted on: Nov 24, 2024
Published on: Apr 30, 2025
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Tomas Leng, Ibrahim Serhat Karakus, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.