Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Comparison of withdrawal times between the control and experimental groups depending on the time morphine was administered_
| Groups | N | Withdrawal time (s) | Statistic test | |
|---|---|---|---|---|
| Mann-Whitney U | P value | |||
| Group control 1 – 0.9% saline | 10 | 5.742 ± 2.452 | 27.500 | 0.089 |
| Group 2 – morphine 5 mg/kg | 10 | 7.658 ± 2.253 | ||
| Group control 3 – 0.9% saline (3h) | 9 | 5.146 ± 2.212 | 12.000 | 0.012* |
| Group 4 - morphine 5 mg/kg (3h) | 9 | 9.187 ± 3.389 | ||
| Group control 5 – 0.9% saline (6 h) | 10 | 3.539 ± 1.161 | 17.000 | 0.011* |
| Group 6 - morphine 5 mg/kg (6 h) | 10 | 5.021 ± 1.427 | ||
| Group control 7 – 0.9% saline (24 h) | 10 | 2.746 ± 0.873 | 23.000 | 0.043* |
| Group 8 - morphine 5 mg/kg (24 h) | 10 | 3.429 ± 0,446 | ||
| Group control 9 – 0,9% saline (48 h) | 10 | 2.980 ± 0.758 | 19.500 | 0.019* |
| Group 10 - morphine 5 mg/kg (48 h) | 10 | 3.836 ± 0.662 | ||
Comparison of withdrawal time between the morphine administration groups
| Groups | N | Withdrawal time (s) | Statistic test | |
|---|---|---|---|---|
| Mann-Whitney U | p value | |||
| Group 2 – morphine 5 mg/kg | 10 | 7.658 ± 2.253 | 30.000 | 0.243 |
| Group 4 - morphine 5 mg/kg (3h) | 9 | 9.187 ± 3.389 | ||
| Group 2 – morphine 5 mg/kg | 9 | 7.658 ± 2.253 | 12.500 | 0.003* |
| Group 6 - morphine 5 mg/kg (6 h) | 9 | 5.021 ± 1.427 | ||
| Group 2 – morphine 5 mg/kg | 10 | 7.658 ± 2.253 | 0.000 | <0.001* |
| Group 8 - morphine 5 mg/kg (24 h) | 10 | 3.429 ± 0.446 | ||
| Group 2 – morphine 5 mg/kg | 10 | 7.658 ± 2.253 | 1.000 | <0.001* |
| Group 10 - morphine 5 mg/kg (48 h) | 10 | 3.836 ± 0.662 | ||
| Group 4 - morphine 5 mg/kg (3h) | 9 | 9.187 ± 3.389 | 11.000 | 0.004 |
| Group 6 - morphine 5 mg/kg (6 h) | 10 | 5.021 ± 1.427 | ||
| Group 4 - morphine 5 mg/kg (3h) | 9 | 9.187 ± 3.389 | 2.000 | <0.001* |
| Group 8 - morphine 5 mg/kg (24 h) | 10 | 3.429 ± 0.446 | ||
| Group 4 - morphine 5 mg/kg (3h) | 9 | 9.187 ± 3.389 | 3.500 | <0.001* |
| Group 10 - morphine 5 mg/kg (48 h) | 10 | 3.836 ± 0.662 | ||
| Group 6 - morphine 5 mg/kg (6 h) | 10 | 5.021 ± 1.427 | 8.000 | 0.001* |
| Group 8 - morphine 5 mg/kg (24 h) | 10 | 3.429 ± 0.446 | ||
| Group 6 - morphine 5 mg/kg (6 h) | 10 | 5.021 ± 1.427 | 20.500 | 0.023 |
| Group 10 - morphine 5 mg/kg (48 h) | 10 | 3.836 ± 0.662 | ||
| Group 8 - morphine 5 mg/kg (24 h) | 10 | 3.429 ± 0.446 | 32.500 | 0.190 |
| Group 10 - morphine 5 mg/kg (48 h) | 10 | 3.836 ± 0.662 | ||