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Is Carboxyhaemoglobin an Effective Bedside Prognostic Tool for Sepsis and Septic Shock Patients? Cover

Is Carboxyhaemoglobin an Effective Bedside Prognostic Tool for Sepsis and Septic Shock Patients?

Open Access
|Nov 2023

References

  1. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810.
  2. Cecconi M, Evans L, Levy M, et al. Sepsis and septic shock. Lancet. 2018;392(10141):75–87.
  3. Rehman FU, Khan A, Aziz A, et al. Neutrophils to Lymphocyte Ratio: Earliest and Efficacious Markers of Sepsis. Cureus. 2020;12(10):e10851.
  4. Drăgoescu AN, Pădureanu V, Stănculescu AD, et al. Neutrophil to Lymphocyte Ratio (NLR)-A Useful Tool for the Prognosis of Sepsis in the ICU. Biomedicines. 2021;10(1):75.
  5. Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med. 2017;43:304–377.
  6. Lazăr A, Georgescu A, Vitin A, Azamfirei L. Precision Medicine and its Role in the Treatment of Sepsis: A Personalised View. The Journal of Critical Care Medicine. 2019;5(3): 90–96.
  7. Zahorec R. Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5–14.
  8. Zahorec R. Neutrophil-to-lymphocyte ratio, past, present and future perspectives. Bratisl Lek Listy. 2021;122(7):474–488.
  9. Farkas JD. The complete blood count to diagnose septic shock. J Thorac Dis. 2020;12(Suppl 1):S16–S21.
  10. Sarı R, Karakurt Z, Ay M, et al. Neutrophil to lymphocyte ratio as a predictor of treatment response and mortality in septic shock patients in the intensive care unit. Turk J Med Sci. 2019;49(5):1336–1349.
  11. Lelubre C, Vincent JL. Mechanisms and treatment of organ failure in sepsis. Nat. Rev. Nephrol. 2018;14:417–427.
  12. McArdle AJ, Webbe J, Sim K, et al. Determinants of Carboxyhemoglobin Levels and Relationship with Sepsis in a Retrospective Cohort of Preterm Neonates. PLoS One. 2016;11(8):e0161784.
  13. Grigorescu BL, Săplăcan I, Bordea IR, et al. Endogenous Carboxyhemoglobin Level Variation in COVID-19 and Bacterial Sepsis: A Novel Approach? Microorganisms 2022;10:305.
  14. Georgescu AM, Szederjesi J, Copotoiu SM, Azamfirei L. Predicting scores correlations in patients with septic shock - a cohort study. Rom J Anaesth Intensive Care. 2014;21(2):95–98.
  15. Wang G, Mivefroshan A, Yaghoobpoor S, et al. Prognostic Value of Platelet to Lymphocyte Ratio in Sepsis: A Systematic Review and Meta-analysis. Biomed Res Int. 2022;2022:9056363.
  16. Almasy E, Szederjesi J, Grigorescu B, et al. The Diagnostic and Prognostic Role of Vascular Endothelial Growth Factor C in Sepsis and Septic Shock. The Journal of Critical Care Medicine. 2020;6(3):152–158.
  17. Hai PD, Viet Hoa LT. The Prognostic Accuracy Evaluation of mNUTRIC, APACHE II, SOFA, and SAPS 2 Scores for Mortality Prediction in Patients with Sepsis. Crit Care Res Pract. 2022;2022:4666594.
  18. Fuchs PA, Czech IJ, Krzych ŁJ. The Pros and Cons of the Prediction Game: The Never-ending Debate of Mortality in the Intensive Care Unit. Int J Environ Res Public Health. 2019;16(18):3394.
  19. Lipinska-Gediga M. Sepsis and septic shock-is a microcirculation a main player? Anaesthesiol Intensive Ther. 2016;48(4):261–265.
  20. Chung J, Chen C, Paw BH. Heme metabolism and erythropoiesis. Curr Opin Hematol. 2012;19(3):156–62.
  21. Palmeri R, Gupta V. Carboxyhemoglobin Toxicity. 2023 Apr 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan–. PMID: 32491811.
  22. Vardar G, Ozek E. Carboxyhemoglobin Levels in Preterm Neonatal Late-Onset Sepsis: to Predict or not to Predict. Mediterr J Hematol Infect Dis. 2023;15(1):e2023017.
  23. Martins EC, Silveira LDF, Viegas K, et al. Neutrophil-lymphocyte ratio in the early diagnosis of sepsis in an intensive care unit: a case-control study. Rev Bras Ter Intensiva. 2019;31(1):64–70.
  24. Ni J, Wang H, Li Y, Shu Y, Liu Y. Neutrophil to lymphocyte ratio (NLR) as a prognostic marker for in-hospital mortality of patients with sepsis: A secondary analysis based on a single-center, retrospective, cohort study. Medicine (Baltimore). 2019;98(46):e18029.
  25. Drewry AM, Samra N, Skrupky LP, et al. Persistent lymphopenia after diagnosis of sepsis predicts mortality. Shock. 2014;42(5):383–91.
  26. Buonacera A, Stancanelli B, Colaci M, Malatino L. Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases. Int. J. Mol. Sci. 2022;23:3636.
  27. Huang Z, Fu Z, Huang W, Huang K. Prognostic value of neutrophil-to-lymphocyte ratio in sepsis: A meta-analysis. Am. J.Emerg. Med. 2020;38:641–647.
  28. Riché F, Gayat E, Barthélémy R, et al. Reversal of neutrophil-to-lymphocyte count ratio in early versus late death from septic shock. Crit Care. 2015;19:439.
  29. Carrola A, Romão CC, Vieira HLA. Carboxyhemoglobin (COHb): Unavoidable Bystander or Protective Player? Antioxidants. 2023;12(6):1198.
  30. Mao Q, Kawaguchi AT, Mizobata S. et al. Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication. Commun Biol. 2021;4:425.
  31. Haines DD, Tosaki A. Heme Degradation in Pathophysiology of and Countermeasures to Inflammation-Associated Disease. Int J Mol Sci. 2020;21(24):9698.
  32. Chan Kai Man, Lam Koon Nga, Endogenous carbon monoxide production in extracorporeal membrane oxygenation-related hemolysis: potential use of point-of-care CO-oximetry carboxyhemoglobin to detect hemolysis. Clinical Case Reports. 2018;6(2):346–349.
DOI: https://doi.org/10.2478/jccm-2023-0031 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 239 - 251
Submitted on: Sep 22, 2023
Accepted on: Oct 22, 2023
Published on: Nov 14, 2023
Published by: University of Medicine, Pharmacy, Science and Technology of Targu Mures
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year

© 2023 Bianca-Liana Grigorescu, Oana Coman, Anca Meda Văsieșiu, Anca Bacârea, Marius Petrișor, Irina Săplăcan, Raluca Ștefania Fodor, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.