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A Farewell to Arms - An Institutional Review of Conventional Staging for Intermediate-Risk Prostate Cancer Cover

A Farewell to Arms - An Institutional Review of Conventional Staging for Intermediate-Risk Prostate Cancer

Open Access
|May 2025

Figures & Tables

Figure 1.

Detection of metastatic disease using both bone scan and CT in Gleason 4+3 intermediate risk disease.
Detection of metastatic disease using both bone scan and CT in Gleason 4+3 intermediate risk disease.

Staging scans performed in patients with missed metastatic disease prior to RALP_

PSA ng/mLMRI T stageBone ScanCT CAPLymph node dissectionBiochemical recurrencePost-op PSMA PET/CT
Patient 118.0T3aNegativeNegativeNegativeYesPositive
Patient 26.4T2cNegativeNot performedNot performedYesNegative
Patient 35.3T3aNegativeNot performedNegativeYesNot performed
Patient 45.5Not performedNegativeNegativePositiveNon/a
Patient 53.9T3aNegativeNegativePositiveNon/a
Patient 64.7T3aNegativeNot performedPositiveNon/a

Patient demographics and staging scans for patients with Gleason 4+3 intermediate risk disease_

Patient demographics (n=134)Median (range or %)
Age72 (45 – 83)
PSA (ng/mL)7.8 (1.8 – 19.3)
Prostate volume (mL)40 (10 – 129)
Biopsy type
TRUS14 (10)
Transperineal120 (90)
MRI prostate (n=130)
PIRADS 215 (11)
PIRADS 39 (7)
PIRADS 466 (51)
PIRADS 540 (31)
MRI T stage
T18 (6)
T274 (57)
T3a48 (37)
MRI N Stage
N0128 (98)
N12 (2)
MRI M stage
M0130 (100)
Bone scan (n=124)
NM Bone scan121 (98)
SPECT CT3 (2)
CT scan (n=83)
CT chest / abdomen / pelvis77 (93)
CT Urogram4 (5)
CTKUB1 (1)
CT abdomen / pelvis1 (1)
Both CT & Bone scan (n=77)77 (53)
Language: English
Page range: 24 - 28
Published on: May 29, 2025
Published by: Shakuat Khanum Memorial Cancer Hospital and Research Centre
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2025 Rustam Karanjia, Pallab Sarkar, Vishnu Basavaraju, Oluwabunmi Tayo, Sashi Kommu, Humayun Bashir, Edward Streeter, published by Shakuat Khanum Memorial Cancer Hospital and Research Centre
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.