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Assessment of urinary paraben levels and associated health risks in adults: a preliminary study on methyl and propyl paraben exposure Cover

Assessment of urinary paraben levels and associated health risks in adults: a preliminary study on methyl and propyl paraben exposure

Open Access
|Oct 2025

Abstract

Parabens, often used as preservatives in consumer products, have raised concerns due to their endocrine-disrupting properties. The aim of this study was to quantify the levels of methyl and propyl paraben in adult urine samples and to assess potential health risks. Using high-performance liquid chromatography (HPLC), methyl and propyl parabens were detected in 20 participants at different concentrations. Methylparaben was more prevalent than propylparaben. Risk assessment was performed by calculating the estimated daily intake (EDI) and the hazard quotient (HQ), with HQ values indicating no significant health risk for the participants. Although current exposure levels appear to be safe, the long-term effects of chronic exposure remain uncertain, highlighting the need for further research. This preliminary study provides insight into paraben exposure in adults and contributes to the growing literature on the safety and prevalence of parabens.

DOI: https://doi.org/10.2478/intox-2025-0004 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 25 - 31
Submitted on: Nov 14, 2024
Accepted on: Jun 2, 2025
Published on: Oct 17, 2025
Published by: Slovak Academy of Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year

© 2025 Ajla Šehović, Amila Turalić, Belma Imamović, Ervina Bečić, Mirza Dedić, Elma Omeragić, published by Slovak Academy of Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.