Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Brijender Bhushan; Prabhu Narain Saxena

doi:10.2478/intox-2018-0014

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Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Interdisciplinary Toxicology

Volume 11 (2018): Issue 2 (August 2018)

By: Brijender Bhushan and Prabhu Narain Saxena

Open Access

|Mar 2019

Abstract

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.

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Articles in this issue

DOI: https://doi.org/10.2478/intox-2018-0014 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853

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Language: English

Page range: 178 - 179

Submitted on: Nov 4, 2016

Accepted on: Oct 3, 2017

Published on: Mar 2, 2019

Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

Related subjects:

Pharmacology, toxicology

© 2019 Brijender Bhushan, Prabhu Narain Saxena, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 11 (2018): Issue 2 (August 2018)