Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Bhushan, Brijender; Saxena, Prabhu Narain

doi:10.2478/intox-2018-0014

Abstract

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.

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Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Abstract

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