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Tetra-ConvBiNet: MRI-based brain tumor classification using distributed tetra head attention-enabled convolutional bidirectional network Cover

Tetra-ConvBiNet: MRI-based brain tumor classification using distributed tetra head attention-enabled convolutional bidirectional network

Open Access
|Jan 2026

Figures & Tables

Figure 1:

Block diagram of the SEnO-DTCBiNet framework. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Block diagram of the SEnO-DTCBiNet framework. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 2:

OFA-based DW-Net model architecture.
OFA-based DW-Net model architecture.

Figure 3:

Bottleneck attention mechanism.
Bottleneck attention mechanism.

Figure 4:

SE attention. SE, squeeze and excitation.
SE attention. SE, squeeze and excitation.

Figure 5:

Structure of ULSAM.
Structure of ULSAM.

Figure 6:

Structural diagram of CC. CC, criss-cross.
Structural diagram of CC. CC, criss-cross.

Figure 7:

Architecture of DTCBiNet. DTCBiNet, distributed tetra head attention-based convolutional bidirectional network.
Architecture of DTCBiNet. DTCBiNet, distributed tetra head attention-based convolutional bidirectional network.

Figure 8:

The flowchart of the SEnO algorithm.
The flowchart of the SEnO algorithm.

Figure 9:

Dataset visualization. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.
Dataset visualization. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.

Figure 10:

Image results based on the BraTS 2020 dataset. ROI, region of interest.
Image results based on the BraTS 2020 dataset. ROI, region of interest.

Figure 11:

BT dataset-based image results. BT, brain tumor; ROI, region of interest.
BT dataset-based image results. BT, brain tumor; ROI, region of interest.

Figure 12:

BraTS 2018 dataset-based image results. ROI, region of interest.
BraTS 2018 dataset-based image results. ROI, region of interest.

Figure 13:

SEnO-DTCBiNet model performance on the BraTS 2020 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
SEnO-DTCBiNet model performance on the BraTS 2020 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 14:

Performance of the SEnO-DTCBiNet model using the BT dataset. BT, brain tumor. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Performance of the SEnO-DTCBiNet model using the BT dataset. BT, brain tumor. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 15:

Performance of SEnO-DTCBiNet model using the BraTS 2018 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Performance of SEnO-DTCBiNet model using the BraTS 2018 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 16:

SEnO-DTCBiNet model performance comparison on the BraTS 2020 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
SEnO-DTCBiNet model performance comparison on the BraTS 2020 dataset. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 17:

K-fold analysis on the BraTS 2020 dataset.
K-fold analysis on the BraTS 2020 dataset.

Figure 18:

Comparison of the SEnO-DTCBiNet model based on the training percentage using the BT dataset. BT, brain tumor. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Comparison of the SEnO-DTCBiNet model based on the training percentage using the BT dataset. BT, brain tumor. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 19:

K-fold analysis on the BT dataset. BT, brain tumor.
K-fold analysis on the BT dataset. BT, brain tumor.

Figure 20:

Comparison of the SEnO-DTCBiNet model based on training percentage using the BraTS 2018 dataset.
Comparison of the SEnO-DTCBiNet model based on training percentage using the BraTS 2018 dataset.

Figure 21:

K-fold based on the BraTS 2018 dataset.
K-fold based on the BraTS 2018 dataset.

Figure 22:

Comparison of the SEnO-DTCBiNet model on the real-time dataset concerning training percentage. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Comparison of the SEnO-DTCBiNet model on the real-time dataset concerning training percentage. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 23:

K-fold analysis on the real-time dataset.
K-fold analysis on the real-time dataset.

Figure 24:

ROC analysis. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.
ROC analysis. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.

Figure 25:

Time complexity analysis. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.
Time complexity analysis. (A) BraTS 2020 dataset, (B) BT dataset, and (C) BraTS 2018 dataset. BT, brain tumor.

Figure 26:

Convergence analysis. SSA, Sparrow Search Algorithm.
Convergence analysis. SSA, Sparrow Search Algorithm.

Figure 27:

Computational complexity analysis in terms of FLOPS. FLOPS, floating-point operations per second.
Computational complexity analysis in terms of FLOPS. FLOPS, floating-point operations per second.

Figure 28:

Ablation study for SEnO-DTCBiNet model components. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.
Ablation study for SEnO-DTCBiNet model components. SEnO-DTCBiNet, sonar energy optimized distributed tetra head attention-based convolutional bidirectional network.

Figure 29:

Ablation study for attention mechanisms. CC, criss-cross; DTHA, distributed tetra head attention; SE, squeeze and excitation.
Ablation study for attention mechanisms. CC, criss-cross; DTHA, distributed tetra head attention; SE, squeeze and excitation.

Figure 30:

Confusion matrix.
Confusion matrix.

T-test analysis based on the BraTS 2020 dataset

MethodsT-test analysis

AccuracyPrecisionRecallF1-score

p-valueT-statisticp-valueT-statisticp-valueT-statisticp-valueT-statistic
EDN-SVM0.122.200.102.390.161.870.132.11
Dense-CNN0.092.420.092.530.122.190.102.36
CJHBA-DRN0.112.210.112.270.122.130.122.19
PatchResNet0.112.240.122.140.102.400.112.28
BA-MCBM0.132.110.112.250.181.760.132.04
2D-CNN-CAE0.132.070.112.220.191.700.142.00
DE-MCBM0.142.020.132.110.161.860.141.98
SSA-DTCBiNet0.122.200.112.220.122.160.122.19
SPO-MCBM0.112.210.122.170.112.280.112.22
SEnO-DTCBiNet0.082.580.112.240.063.000.072.71

Results of the SEnO-DTCBiNet and baseline models based on training percentage

Methods/metricsDE-MCBMPatch ResNetEDN-SVMDense-CNN2D-CNN-CAECJHBA-DRNBA-MCBMSSA-DTCBiNetSPO-MCBMSEnO-DTCBiNet
BraTS 2020 datasetPrecision (%)91.1187.9085.3383.4289.3687.3390.2290.6795.4997.30
Recall (%)96.2493.7392.9291.9095.4893.3796.0796.1597.7797.88
Accuracy (%)93.6789.8987.4086.1990.7288.8191.2492.4696.5397.17
F1-Score (%)93.6190.7288.9687.4592.3290.2593.0593.3396.6297.25

BT datasetPrecision (%)94.3989.0486.7385.0990.1286.7490.5795.5596.7196.86
Recall (%)96.1593.1492.5191.7494.7492.9795.8397.3398.5298.72
Accuracy (%)94.3091.3589.0588.5791.7891.1391.8296.1197.9198.48
F1-Score (%)95.26391.0589.5388.2992.3789.7593.12896.4397.6197.98

BraTS 2018 datasetPrecision (%)93.1491.6589.9589.3392.7690.0993.0893.4993.8994.16
Recall (%)94.7592.8290.6090.1593.0192.7294.0695.4597.0397.42
Accuracy (%)95.5994.0589.9188.1694.1391.2194.3095.6996.8097.76
F1-Score (%)93.9492.2390.2789.7492.8891.3993.5694.4695.4395.76

Real-time datasetPrecision (%)94.8093.2791.6290.4593.9691.7394.2495.2995.3195.99
Recall (%)95.8894.5792.9392.5694.8893.8595.1396.8997.0397.10
Accuracy (%)95.1693.7092.0691.1594.2792.4494.5495.8295.8896.36
F1-Score (%)95.3493.9292.2791.4994.4292.7894.6896.0896.1696.54

Real-time dataset-based statistical analysis

Methods/metricsDense-CNNEDN-SVMCJHBA-DRNPatch ResNet2D-CNN-CAEBA-MCBMDE-MCBMSSA-DTCBiNetSPO-MCBMSEnO-DTCBiNet
AccuracyBest88.0090.4691.2392.9293.6694.5295.3895.5295.5896.48
Mean84.1785.4586.6887.5988.5989.3490.3190.9091.6893.11
Variance6.3011.0811.8914.7416.7415.9113.4012.309.846.77
Standard deviation2.513.333.453.844.093.993.663.513.142.60

PrecisionBest89.6590.0390.8392.4193.5093.5494.3994.5594.6195.78
Mean84.9485.5586.2987.1288.2088.7089.8390.5490.7192.31
Variance9.449.6910.0413.5717.2113.7010.5010.229.996.81
Standard deviation3.073.113.173.684.153.703.243.203.162.61

RecallBest84.7191.3392.0493.9693.9696.4797.3497.4597.5197.87
Mean82.6285.2587.4788.5489.3690.6191.2591.6293.6294.71
Variance1.9814.5316.8517.5015.9920.9520.6217.649.586.74
Standard deviation1.413.814.104.184.004.584.544.203.092.60

F1-scoreBest87.7390.6191.3592.7593.3194.2495.4896.3196.5396.63
Mean84.7685.8186.7387.5988.2988.9689.7390.6191.0993.16
Variance4.3710.0112.1915.0312.0713.6014.8315.5013.609.17
Standard deviation2.093.163.493.883.473.693.853.943.693.03

BT dataset-based statistical analysis

Methods/metricsSSA-DTCBiNetDense-CNNBA-MCBMMEDN-SVM2D CNN-CAECJHBA-DRNPatch ResNetDE-MCBMSPO-MCBMSEnO-DTCBiNet
AccuracyBest95.2489.3294.8491.4994.7192.1992.9194.9795.6396.24
Mean90.8985.4489.2186.2188.5187.3587.9490.3691.8093.10
Variance16.569.6619.5814.0719.3114.6314.8117.2914.618.64
Standard deviation4.073.114.433.754.393.823.854.163.822.94

PrecisionBest94.0589.7393.5990.6293.5391.0591.3793.7394.6095.49
Mean90.4185.6488.6186.0688.2687.0387.5990.1191.4493.02
Variance12.5010.4814.2211.8314.3110.839.8212.1211.314.85
Standard deviation3.543.243.773.443.783.293.133.483.362.20

RecallBest97.6388.4997.3493.2397.0794.4996.0097.4797.6997.72
Mean91.8685.0590.4186.4989.0088.0088.6490.8692.5393.27
Variance26.478.2433.8119.7031.9424.1128.3730.9122.6220.79
Standard deviation5.142.875.824.445.654.915.335.564.764.56

F1-scoreBest95.8189.1195.4391.9195.2792.7493.6395.5696.1296.59
Mean91.1285.3489.4986.2788.6287.5088.0990.4791.9893.12
Variance18.719.2722.5215.2922.0316.6817.5920.2016.3711.21
Standard deviation4.333.044.753.914.694.084.194.494.053.35

Hyperparameters of the SEnO-DTCBiNet model

HyperparametersValues
Kernel size(3 × 3)
Pooling(2,2)
Convolution 2D layers2
Activation functionReLU
Learning rate0.02
Dropout rate0.5
No. of BiLSTM layers2
LSTM Units64
Loss functionCategorical-cross entropy
OptimizerAdam
Number of epochs100
PoolingMaxPooling2D
MetricsAccuracy
PaddingSame
Stride size2

BraTS 2018 dataset-based statistical analysis

Methods/metricsDense-CNNEDN-SVMCJHBA-DRNPatchRes Net2D-CNN-CAEBA-MCBMDE-MCBMSSA-DTCBiNetSPO-MCBMSEnO-DTCBiNet
AccuracyBest89.1189.8191.6092.6293.1793.7594.2294.5994.7895.51
Mean84.8585.6487.0087.8788.9589.3989.9490.2390.9692.12
Variance7.407.5311.5112.3312.9113.8315.5215.2114.4011.72
Standard deviation2.722.743.393.513.593.723.943.903.793.42

PrecisionBest90.3591.2591.8593.0393.6694.0494.5694.8394.9595.37
Mean85.4086.2887.4287.9389.1489.5890.2290.4891.1791.98
Variance10.3210.3011.2312.6313.3513.6015.3914.5715.8514.38
Standard deviation3.213.213.353.553.653.693.923.823.983.79

RecallBest86.6486.9591.1091.8192.1893.1693.5494.1394.4395.80
Mean83.7684.3786.1787.7388.5789.0289.3689.7390.5592.40
Variance3.093.4412.4412.2712.3614.4616.1816.6811.997.68
Standard deviation1.761.853.533.503.523.804.024.083.462.77

F1-scoreBest88.4689.0591.4892.4292.9293.6094.0594.4894.6995.58
Mean84.5785.3186.7987.8388.8589.3089.7990.1090.8692.19
Variance6.066.2311.7112.2312.7313.9615.6415.5713.7410.58
Standard deviation2.462.503.423.503.573.743.953.953.713.25

BraTS 2018 dataset-based T-test analysis

Methods/metricsT-test analysis

PrecisionAccuracyF1-scoreRecall

p-valueT-statisticp-valueT-statisticp-valueT-statisticp-valueT-statistic
SSA-DTCBiNet0.072.730.072.720.072.720.072.69
EDN-SVM0.132.080.132.090.132.100.132.10
CJHBA-DRN0.102.370.112.230.122.150.151.94
PatchResNet0.112.230.112.290.102.310.102.37
Dense-CNN0.171.800.171.780.181.770.191.68
BA-MCBM0.082.660.082.670.082.670.082.67
DE-MCBM0.072.780.072.750.072.730.082.66
2D-CNN-CAE0.082.640.082.680.072.690.072.72
SPO-MCBM0.072.780.072.720.082.680.082.54
SEnO-DTCBiNet0.072.720.072.730.072.720.082.66

Real-time dataset-based T-test analysis

Methods/metricsT-test analysis

PrecisionF1-scoreAccuracyRecall

p-valueT-statisticp-valueT-statisticp-valueT-statisticp-valueT-statistic
PatchResNet0.102.300.102.350.102.340.102.39
EDN-SVM0.112.250.142.030.132.100.171.83
CJHBA-DRN0.112.290.092.510.092.450.082.63
SPO-MCBM0.092.440.102.390.102.410.102.34
2D-CNN-CAE0.102.350.102.340.102.340.102.32
BA-MCBM0.102.320.112.250.112.270.122.19
DE-MCBM0.112.290.122.200.112.230.122.12
SSA-DTCBiNet0.092.440.122.180.112.260.141.96
Dense-CNN0.132.040.141.970.142.000.171.79
SEnO-DTCBiNet0.122.130.122.170.122.160.112.22

Features based on statistical deep flow

FeaturesDescriptionMathematical notationOutput size
MeanIt is the ratio between the total intensity of all pixels and the total number of pixels within the deep flow feature image. T1=1ri=1rφi {T_1} = {1 \over r}\sum\limits_{i = 1}^r {{\varphi _i}} [N,120,120,1]
where φi is the feature and r the total images.
KurtosisKurtosis is defined as the shape of the selected images taken for the statistical measurement. T2=T1T1¯4rT3 {T_2} = {{\sum {{{\left( {{T_1} - \overline {{T_1}} } \right)}^4}} } \over {r\left( {{T_3}} \right)}} [N,120,120,1]
T2 is the kurtosis
Standard deviationThe standard deviation is defined as the square root of the variance and represents the average deviation of each pixel intensity from the mean. T3=1ri=1rφiT12 {T_3} = \sqrt {{1 \over r}\sum\limits_{i = 1}^r {{{\left( {{\varphi _i} - {T_1}} \right)}^2}} } [N,120,120,1]
standard deviation is denoted as T3
SkewSkewness is defined as a measure of symmetry of the image. T4=1ri=1rφiT1T3 {T_4} = {1 \over r}\sum\limits_{i = 1}^r {\left[ {{{{\varphi _i} - {T_1}} \over {{T_3}}}} \right]} [N,120,120,1]
T4 Is the skew
VarianceVariance is defined as the square of the standard deviation. T5=T32=1ri=1rφiT12 {T_5} = {\left( {{T_3}} \right)^2} = {1 \over r}\sum\limits_{i = 1}^r {{{\left( {{\varphi _i} - {T_1}} \right)}^2}} [N,120,120,1]
T5 Is the variance

T-test Analysis based on the BT dataset

Methods/metricsT-test analysis

PrecisionF1-scoreAccuracyRecall

p-valueT-statisticp-valueT-statisticp-valueT-statisticp-valueT-statistic
DE-MCBM0.092.540.102.360.092.410.112.24
EDN-SVM0.141.980.141.960.141.970.151.92
CJHBA-DRN0.102.370.112.250.112.290.122.17
PatchResNet0.092.420.112.220.112.280.132.08
Dense-CNN0.132.050.122.200.122.150.102.35
BA-MCBM0.102.380.112.250.112.290.122.15
2D-CNN-CAE0.102.310.122.160.122.200.132.04
SSA-DTCBiNet0.082.620.082.560.082.580.092.51
SPO-MCBM0.072.770.072.710.072.730.082.66
SEnO-DTCBiNet0.102.310.072.700.082.620.072.83

Features based on GLCM

FeaturesOverviewFormulaDimensions of outputs
HomogeneityHomogeneity calculates the similarity of the texture in the distributed gray-level object pairs. E3=kln1Mkl1+kl {E_3} = \sum\limits_{kl}^{n - 1} {{{{M_{kl}}} \over {1 + \left| {k - l} \right|}}} [N,120,120,1]
homogeneity feature is represented as E3.
EnergyEnergy is used to calculate the uniformity of an image. E1=kln1Mkl2 {E_1} = \sum\limits_{kl}^{n - 1} {{{\left( {{M_{kl}}} \right)}^2}} [N,120,120,1]
E1 It is the energy feature, and GLCM of the image Q is denoted as Mkl.
EntropyEntropy reproduces the complexity of an image present in the GLCM features. E4=kln1Mkllog2Mkl {E_4} = \sum\limits_{kl}^{n - 1} {{M_{kl}}{{\log }_2}\left( {{M_{kl}}} \right)} [N,120,120,1]
E4 Represents the entropy.
ContrastContrast calculates the local variation amounts present in the image. E5=kln1M(kl)2 {E_5} = \sum\limits_{kl}^{n - 1} {M{{(k - l)}^2}} [N,120,120,1]
E5 Depicts the contrast.
DissimilarityIt measures the gaps between the mean variances and ROI in the gray-scale image E2=kln1Mklkl {E_2} = \sum\limits_{kl}^{n - 1} {{M_{kl}}\left| {k - l} \right|} [N,120,120,1]
E2 Denotes the dissimilarity feature of GLCM.

Results of the SEnO-DTCBiNet model and comparative methods based on K-fold

Methods/metrics2D-CNN-CAEDE-MCBMDense-CNNCJHBA-DRNPatch ResNetEDN-SVMBA-MCBMSSA-DTCBiNetSPO-MCBMSEnO-DTCBiNet
BraTS 2020 datasetPrecision (%)92.5093.6587.5789.8192.2489.3393.2295.1195.3995.53
Recall (%)94.1497.3887.8992.9493.2691.9295.2897.5597.6997.75
Accuracy (%)93.0594.8987.6890.8592.5890.1993.9195.9296.1696.27
F1-Score (%)93.3195.4887.7391.3592.7590.6194.2496.3196.5396.63

BT datasetPrecision (%)93.5393.7389.7391.0591.3790.6293.5994.0594.6095.49
Recall (%)97.0797.4788.4994.4996.0093.2397.3497.6397.6997.72
Accuracy (%)94.7194.9789.3292.1992.9191.4994.8495.2495.6396.24
F1-Score (%)95.2795.5689.1192.7493.6391.9195.4395.8196.1296.59

BraTS 2018 datasetPrecision (%)93.6694.5690.3591.8593.0391.2594.0494.8394.9595.37
Recall (%)92.1893.5486.6491.1091.8186.9593.1694.1394.4395.80
Accuracy (%)93.1794.2289.1191.6092.6289.8193.7594.5994.7895.51
F1-Score (%)92.9294.0588.4691.4892.4289.0593.6094.4894.6995.58

Real-time datasetPrecision (%)93.5094.3989.6590.8392.4190.0393.5494.5594.6195.78
Recall (%)93.9697.3484.7192.0493.9691.3396.4797.4597.5197.87
Accuracy (%)93.6695.3888.0091.2392.9290.4694.5295.5295.5896.48
F1-Score (%)93.7395.8487.1191.4393.1790.6794.9995.9896.0496.82

BraTS 2020 dataset-based statistical analysis

Methods/metricsPatchRes NetBA-MCBMDense-CNNCJHBA-DRNEDN-DRN2D-CNN-CAESPO-MCBMSSA-DTCBiNetDE-MCBMSEnO-DTCBiNet
AccuracyBest92.5893.9187.6890.8590.1993.0594.8995.9296.1696.27
Mean87.4088.5984.8186.4985.7887.9689.3390.2490.7092.34
Variance14.6513.724.2710.559.0312.6314.0515.2813.5010.02
Standard deviation3.833.702.073.253.013.553.753.913.673.16

PrecisionBest92.2493.2287.5789.8189.3392.5093.6595.1195.3995.53
Mean87.0287.8084.9285.9885.6987.2888.5089.4689.8990.51
Variance13.9414.224.097.567.3114.0412.4514.8513.3112.81
Standard deviation3.733.772.022.752.703.753.533.853.653.58

RecallBest93.2695.2887.8992.9491.9294.1497.3897.5597.6997.75
Mean88.1790.1784.5987.5085.9489.3491.0091.7892.3195.99
Variance16.3413.514.7618.4113.7610.4317.6816.2613.957.93
Standard deviation4.043.682.184.293.713.234.204.033.742.82

F1-scoreBest92.7594.2487.7391.3590.6193.3195.4896.3196.5396.63
Mean87.5988.9684.7686.7385.8188.2989.7390.6191.0993.16
Variance15.0313.604.3712.1910.0112.0714.8315.5013.609.17
Standard deviation3.883.692.093.493.163.473.853.943.693.03
Language: English
Submitted on: Aug 22, 2025
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Published on: Jan 30, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 Aasha Mahesh Chavan, Vanita Mane, published by Professor Subhas Chandra Mukhopadhyay
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.