Have a personal or library account? Click to login
A Survey of Distributed Ledger Technologies in the Health Domain Cover

A Survey of Distributed Ledger Technologies in the Health Domain

Open Access
|Feb 2025

Figures & Tables

Figure 1.

PRISMA Workflow, n is the number of research articles
PRISMA Workflow, n is the number of research articles

Figure 2.

Distributed ledger technology’s (DLT) framework concept
Distributed ledger technology’s (DLT) framework concept

Comparison chart of blockchain networks and the Transaction Fee (Dollars) and Speed (Transaction Per Second)

NameTransaction fee (Dollar)Speed (TPS)
Ethereum (ETH)10 to 10015-30
Tether (USDT)1.0015-30
BNB1.001000
Solana (SOL)0.0165,000
XRP0.011,500
Avalanche (AVAX)0.01 - 0.054500+
TRON (TRX)0.001 - 0.0052000+
Polkadot (DOT)0.01 - 0.101000+
Polygon (MATIC)0.001 - 0.0057500+
Bitcoin Cash (BCH)0.001 - 0.0560+
Cosmos (ATOM)0.01 - 0.10100+
Stacks (STX)0.01 - 0.1030+
Ethereum Classic (ETC)0.01 - 0.1015+
Hedera (HBAR)0.0001 - 0.00110,000+
NEAR Protocol0.01 - 0.054000+

Types of Blockchain

Pubic BlockchainPrivate BlockchainConsortium Blockchain
PermissionPublicPrivatePublic or Private
OrganizationDecentralizedPartially DecentralizedAlmost Decentralized
SecurityHighMediumMedium
CostHighMediumLow
IdentityAnonymousIdentifiedIdentified
ExampleBitcoin, EthereumCompany internalHyperledger, Corda

Comparison chart of blockchain implementations in healthcare

NameYearpublic/private BCFrameworkLanguage implementation
MedRec[58]2016Private blockchain (permissioned)Ethereum, PyEthereumSolidity (for smart contracts)
Medicalchain[59]2018Public blockchain (permissioned for certain features)Hyperledger FabricGo (Golang)
SimplyVital Health2017Public blockchain (permissioned for certain features)Ethereum blockchainSolidity (for smart contracts)
ProvChain[60]2017Not specified (proprietary implementation)Private Permissionedplatform-independent library
Patientory[61]2015Private blockchain (permissioned)Ethereum blockchainPTOY and solidity
IBM Blockchain Healthcare[62]2017Private blockchain (permissioned)Hyperledger FabricGo (Golang)
Gem Health Network2016Public blockchain (permissioned for certain features)Ethereum blockchainSolidity (for smart contracts)
Hashed Health2016Private blockchain (permissioned)Hyperledger FabricGo (Golang)
Tierion2015Public blockchain (anchoring data to Bitcoin blockchain)Bitcoin blockchainJavaScript
Factom2015Public blockchain (Factom Protocol)Factom ProtocolGo (Golang)
MedicalDao2017Public blockchain (permissioned)Ethereum blockchainSolidity (for smart contracts)
Health Nexus2018Public blockchain (permission for certain features)Ethereum blockchainSolidity (for smart contracts)
Blockchain Health Co.2017Not specified (likely a mix of public and private)Ethereum blockchainSolidity (for smart contracts)
MediBloc[63]2017Public blockchain(MediBloc Network)Ethereum blockchainSolidity (for smart contracts)
Nebula Genomics[64]2018Public blockchain (Gene-Chain)Ethereum blockchainSolidity (for smart contracts)

Distributed Ledger Technology Key benefits and use cases in bio medical healthcare

Distributed Ledger Technology Key benefitsImprove medical record managementEnhance insurance claim processAccelerate ResearchAdvance healthcare data
Decentralized ManagementThe distributed ledger technology and digital wallets enable patients to manage their health record online. This removes all obstacles for gaining access or transferring of their medical data to another healthcare provider [66].Real time claim processing becomes easy and transparent by replacing the health plan intermediation with transparent blockchain technology [67].Institutions can keep full control of their computational resources while collaborating with other institutes by sharing data and analysis [68].Decentralized health data becomes the backbone for digital health, incorporating data from patient-based and EMR systems to provide a data-pool, from which authorized users can access it [69].
Immutable Audit TrailThe data is unalterable, the stored data on private blockchain cannot be changed by anybody including healthcare providers and patients [70].Based on blockchain immutability, claim auditing and fraud detection becomes more smooth for the payer and insurers [71].Personal patient generated data with timestamp is available, this trackable data is available to research[72].The distributed network of nodes contains the timestamped, tamper proof, continuously updated data. This could be adapted for basic and experimental model science.
Data ProvenanceThe medical records are verifiable and signed by the source, false records are plausibly denied [73].The distributed Ledger Technology can address the problem of distributed nature of records with blockchain[74].The MedRec Blockchian based health record and medical research data is enabled with crucial properties of provenance [75].Altered and low quality medicine can be tracked and identified. Using blockchain the origin of the medicine product can be traced and transfer of ownership is clear and available to everyone [72].
Robustness/AvailabilityDecentralized network advantage is that no single institution can be hacked or robbed to obtain a large number of patient records [66].Enhance accessibility of patient data through decentralized ledger with online data access [71].Healthcare data availability across the globe online for research and advancement of science and technology with decentralized blockchain networks. Real time data is accessible to improve emergency medical situations [76].Blockchain enabled anti tampering capabilities during manufacturing, supply and disposition systems, which could make drug counterfeiting a non-issue [71].
Security/PrivacyThe data is encrypted and only accessible with the private key of the patient. Even if the network is infiltrated the data is not readable [66].Financial information is secured with the block chain mechanism [71].Individuals, healthcare providers, healthcare entities and medical researchers share vast amounts of genetic, diet, lifestyle, environmental and health data with security and privacy protection [76].Patient centric consent management system.
DOI: https://doi.org/10.2478/ias-2024-0017 | Journal eISSN: 1554-1029 | Journal ISSN: 1554-1010
Language: English
Page range: 249 - 265
Published on: Feb 21, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2025 Ikramullah Khan, Sudip Phuyal, Ricardo Correia, Joao C. Ferreira, published by Cerebration Science Publishing Co., Limited
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.