Fig. 1.

Fig. 2.

Fig. 3.

Mebendazole and its derivative in control of nematode infection_
| Parasite | Group | Drug | Pre Treatment (Mean ± SD) | Post treatment (Mean ± SD) | Reduction % | P-value |
|---|---|---|---|---|---|---|
| Ascaridia galli | X | Control | 340 ± 40 | 370 ± 40 | 0 | 0.18 |
| Y | Derivative | 340 ± 50 | 30.6 ± 50 | 91 | 0.0001*** | |
| Z | Mebendazole | 340 ± 60 | 74.8 ± 60 | 78 | 0.0001*** | |
| Capillaria spp. | X | Control | 250 ± 35 | 265 ± 35 | 0 | 0.3 |
| Y | Derivative | 250 ± 45 | 30 ± 45 | 88 | 0.0001*** | |
| Z | Mebendazole | 250 ± 55 | 75 ± 55 | 70 | 0.0001*** | |
| H. gallinarum | X | Control | 280 ± 38 | 310 ± 38 | 0 | 0.13 |
| Y | Derivative | 280 ± 48 | 28 ± 48 | 90 | 0.0001*** | |
| Z | Mebendazole | 280 ± 50 | 72.8 ± 50 | 74 | 0.0001*** | |
| Trichuris spp. | X | Control | 220 ± 32 | 235 ± 32 | 0 | 0.23 |
| Y | Derivative | 220 ± 42 | 17.6 ± 42 | 92 | 0.0001*** | |
| Z | Mebendazole | 220 ± 53 | 55 ± 53 | 75 | 0.0001*** | |
Multivariate Logistic Regression Analysis of Associated Risk Factors in Chickens (n= 456)_
| Variable | Category | Examined (n) | Infected (n) | Prevalence (%) | OR | 95% CI | P-value |
|---|---|---|---|---|---|---|---|
| Gender | Male | 189 | 130 | 68.6 | Ref | — | — |
| Female | 267 | 200 | 74.8 | 1.47 | 1.01 – 2.17 | 0.044* | |
| Age | Young | 274 | 233 | 85 | Ref | — | — |
| Old | 182 | 97 | 53.3 | 0.25 | 0.16 – 0.41 | 0.001*** | |
| Body condition | Healthy | 317 | 204 | 64.4 | Ref | — | — |
| Weak | 139 | 126 | 90.6 | 3.85 | 2.23 – 6.63 | 0.001*** | |
| Rearing System | Semi-intensive | 101 | 75 | 71.8 | Ref | — | — |
| Free range | 355 | 255 | 74.3 | 1.54 | 1.02 – 2.32 | 0.039* | |
| Feeding Type | Additional feed | 112 | 83 | 71.1 | Ref | — | — |
| Scavenging | 344 | 247 | 74.8 | 1.41 | 1.00 – 2.29 | 0.047* | |
| Deworming Status | Yes | 100 | 69 | 69 | Ref | — | — |
| No | 356 | 261 | 73.3 | 1.61 | 1.03 – 2.63 | 0.036* | |
| Locality | Swat | 152 | 105 | 69.1 | Ref | — | — |
| Malakand | 151 | 114 | 75.5 | 1.49 | 1.02 – 2.18 | 0.041* | |
| Lower Dir | 153 | 111 | 72.5 | 1.32 | 0.87 – 1.99 | 0.18 | |