Abstract
The major aim of the paper is to summarize the main paths of regional development in the Czech Republic during the period of political, economical and societal transition using the statistical data and own survey at the country level. Following this summary, we aim at differentiation of regional developmental paths at individual hierarchical levels. Our analyses shows that structured assessment of quality of socio-economic environment at the regional respectively meso-regional level provides the necessary information needed for creation and implementation of effectively decentralized regional policy.