Effectiveness of the combination of Fe tablets and beetroot juice in increasing Hb levels of pregnant women with anemia†

Amini, Aulia; Nurbaety, Baiq

doi:10.2478/fon-2025-0047

Abstract

Objective

This study aims to determine the effectiveness of giving a combination of Fe tablets and beetroot juice in increasing hemoglobin (Hb) levels of pregnant women with anemia in the Mataram City area.

Methods

This study was designed with quasi-experimental design with pre-test and post-test with control design. The location of this study was conducted in the city of Mataram on pregnant women with anemia. The sample of this study was pregnant women with mild anemia based on inclusion and exclusion criteria, divided into 2 groups: a control group and a treatment group of 15 respondents each, bringing the total respondents to 30 people. Analysis of Hb level measurement results was carried out using the independent sample t-test.

Results

The results obtained in the treatment group (combination of beet juice and Fe tablets) were the mean pre-test of 9.93 mg/dL and post-test of 11.90 mg/dL (P-value = 0.000), which means there is effectiveness in increasing hemoglobin levels while in the control group. Comparison of increased Hb levels of the control group and significantly different treatments marked by a P value of 0.001.

Conclusions

the combination of Fe tablets and beetroot juice is effective in increasing Hb levels of pregnant women with anemia in the Mataram City area.

References

Saifuddin AB, editor. Buku Panduan Praktis Pelayanan Kesehatan Maternal dan Neonatal. Jakarta: Yayasan Bina Pustaka Sarwono Prawirohardjo; 2002.
Search in Google Scholar Back to article
World Health Organization. World Health Statistics 2015. Geneva: World Health Organization; 2015.
Search in Google Scholar Back to article
Kemenkes RI. Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI. 2018;53:1689–1699.
Search in Google Scholar Back to article
Prawirohardjo S, editor. Ilmu Kebidanan Sarwono Prawirohardjo. Jakarta: PT Bina Pustaka Sarwono Prawirohardjo; 2010.
Search in Google Scholar Back to article
Kefarmasian S, Kesehatan DANA. Dinas kesehatan provinsi ntb. 2019:239007.
Search in Google Scholar Back to article
Cotoraci C, Ciceu A, Sasu A, et al. Natural antioxidants in anemia treatment. Int J Mol Sci. 2021;22:1–29.
Search in Google Scholar Back to article
Kuma MN, Tamiru D, Belachew T. Hemoglobin level and associated factors among pregnant women in rural Southwest Ethiopia. Biomed Res Int. 2021;2021:9922370.
Search in Google Scholar Back to article
Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN. Living with water stress: evolution of osmolyte systems. Annu Rev Physiol. 1982;44:31–50.
Search in Google Scholar Back to article
Wakwoya EB, Belachew T, Girma T. Determinants of nutritional status among pregnant women in East Shoa zone, Central Ethiopia. Front Nutr. 2022;9:958591.
Search in Google Scholar Back to article
Suryandari AE, Happinasari O. Comparison of increased HB levels in pregnant women given Fe with Fe and beetroot in the working area of the South Purwokerto Health Center. Journal of Mid-wifery. 2015;7:36–47.
Search in Google Scholar Back to article
Tan J, He G, Qi Y, et al. Prevalencia de anemia y anemia por deficiencia de hierro en mujeres embarazadas chinas (IRON WOMEN): una encuesta transversal nacional. BMC Pregnancy Childbirth. 2020;20:1–12.
Search in Google Scholar Back to article
Setyiyaningsih S, Kritiningrum W. The effectiveness of beetroot and lemon juice in increasing HB levels in pregnant women. JURNAL KEBIDANAN. 2020;6:71–76.
Search in Google Scholar Back to article
Clifford T, Howatson G, West DJ, et al. The potential benefits of red beetroot supplementation in health and disease. Nutrients. 2015;7:2801.
Search in Google Scholar Back to article
Lestari Y, Wahara W, Sembiring JB, et al. The Effect of Giving Bit Juice With Prevention of Anemia in Pregnant Women in Trimester III at the Clinic of Dina Karya Medan in 2021. Institut Kesehatan Helvetia Medan. Vol. 4. Jl. Kapten Sumarsono: Pangkalan Masyhur; 2022.
Search in Google Scholar Back to article
Abu-Ouf NM, Jan MM. The impact of maternal iron deficiency and iron deficiency anemia on child’s health. Saudi Med J. 2015;36:146.
Search in Google Scholar Back to article
Agustina R, Wirawan F, Sadariskar AA, et al. Associations of knowledge, attitude, and practices toward anemia with anemia prevalence and height- for-age z-score among Indonesian adolescent girls. Food Nutr Bull. 2021;42(1_suppl):S92–108.
Search in Google Scholar Back to article
Mariza A. Hubungan pendidikan dan sosial ekonomi dengan kejadian anemia pada ibu hamil di BPS T Yohan Way Halim Bandar Lampung tahun 2015. Jurnal Kesehatan Holistik. 2016;10:5–8 (In Indonesian).
Search in Google Scholar Back to article
Garzon S, Cacciato PM, Certelli C, et al. Iron deficiency anemia in pregnancy: novel approaches for an old problem. Oman Med J. 2020;35:e166.
Search in Google Scholar Back to article
Miller JL. Iron deficiency anemia: a common and curable disease. Cold Spring Harb Perspect Med. 2013;3:a011866.
Search in Google Scholar Back to article
Maulidanita R, Mardiah A. The effect of date juice to increase of hemoglobin levels on pregnant woman anemia. Jurnal Kesehatan LLDIKTI Wilayah. JUKES. 2021;1.
Search in Google Scholar Back to article
Li N, Zhao G, Wu W, et al. The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: a randomized clinical trial. JAMA Netw Open. 2020;3:e2023644.
Search in Google Scholar Back to article
Bone JN, Bellad M, Goudar S, et al. Anemia and adverse outcomes in pregnancy: subgroup analysis of the CLIP cluster-randomized trial in India. BMC Pregnancy Childbirth. 2022;22:1–11.
Search in Google Scholar Back to article
Tan ML, Hamid SBS. Beetroot as a potential functional food for cancer chemoprevention, a narrative review. J Cancer Prev. 2021;26:1.
Search in Google Scholar Back to article
Zahyrah S, Dondi S, Wijayanti I, et al. Effectiveness of beta vulgaris L (BIT) juice to increase haemoglobin levels in pregnant women anemia at Primary Health Care Kotaraja. Journal of Midwifery Science: Basic and Applied Research. 2020;2: 48–53.
Search in Google Scholar Back to article
Wenda S, Utami S, Elita V. Efektivitas pemberian jus buah bit terhadap kadar hemoglobin ibu hamil dengan anemia. Quarterly J Knowl Inform Manag. 2016;3:49–59 (In Indonesian).
Search in Google Scholar Back to article
Stephana W, Utami S, Elita V, et al. EFEKTIVITAS PEMBERIAN JUS BUAH BIT TERHADAP KADAR HEMOGLOBIN IBU HAMIL DENGAN ANEMIA. Jurnal Online Mahasiswa (JOM) Bidang Ilmu Keperawatan. 2018;5:334–341.
Search in Google Scholar Back to article
Kenjale AA, Ham KL, Stabler T, et al. Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. J Appl Physiol (1985). 2011;110:1582–1591.
Search in Google Scholar Back to article
Rusmiati1 D. Pengaruh Zat Besi PENGARUH PEMBERIAN SUPLEMEN ZAT BESI DENGAN DAN TANPA VITAMIN C TERHADAP KENAIKAN KADAR HEMOGLOBIN IBU HAMIL. Jurnal Ilmiah Bidan. 2019;4.
Search in Google Scholar Back to article
Manan A, Dinengsih KS, Siauta JA. The effect of date fruit consumption on hemoglobin levels in pregnant women in trimester III. Jurnal Midpro. 2021;13:78–84.
Search in Google Scholar Back to article
Pratiwi R, Widari D. Hubungan Konsumsi Sumber Pangan Enhancer Dan Inhibitor Zat Besi Dengan Kejadian Anemia Pada Ibu Hamil. Amerta Nutrition. 2018;2:283–291.
Search in Google Scholar Back to article
Liliana C, Oana-Viorela N. Red beetroot: composition and health effects - A review. J Nutr Med Diet Care. 2020;5.
Search in Google Scholar Back to article
Puspita AJ, Anjar J, Puspita P, et al. The effect of iron supplement and vitamin c towards increasing hemoglobin levels in pregnant woman with anemia. Jurnal Medika Hutama. 2021;2:1060–1066.
Search in Google Scholar Back to article
Al-Alimi AA, Bashanfer S, Morish MA. Prevalence of iron deficiency anemia among university students in Hodeida Province, Yemen. Anemia. 2018;2018:4157876.
Search in Google Scholar Back to article
Al-Shwyeh HA. Date palm (Phoenix dactylifera L.) fruit as potential antioxidant and antimicrobial agents. J Pharm Bioallied Sci. 2019;11:1.
Search in Google Scholar Back to article
Othman SME, Fleet JA, Steen M, Jayasekara R. Midwives’ views and experiences of providing healthy eating advice to pregnant women: a qualitative content analysis of semi-structured interviews. Front Nurs. 2020;7:345–358.
Search in Google Scholar Back to article