Factors predicting fatigue among patients undergoing hemodialysis

Variables	N	%
Age (years)
18-30	33	16.5
30-50	105	52.5
≥ 50	62	31.0
Gender
Male	97	48.5
Female	103	51.5
Working Status
Working	82	41.0
Not working	118	59.0
Marital status
Single	36	18.0
Married	104	52.0
Widow/divorce	60	30.0
Level of Education
Primary	61	30.5
Secondary	97	48.5
Bachelor	38	19.0
Postgraduate	4	2.0
History of hemodialysis, years
< 1	49	24.5
1 to < 5	62	31.0
5 to < 10	64	32.0
≥ 10	25	12.5
Frequency of dialysis sessions/Week
Two	37	18.5
Three	163	81.5
Duration of hemodialysis sessions, hours
< 3	8	2.0
3	41	20.5
4	151	75.5

Table 2.

Fatigue levels among study subjects as measured by the Piper Fatigue Scale (N=200).

Piper Fatigue Scale Sub-dimensions	Mild		Moderate		Sever		Mean	SD
Piper Fatigue Scale Sub-dimensions	N	%	N	%	N	%	Mean	SD
Behavioral/Severity	13	6.5	162	81.0	25	12.5	34.69	9.9
Affective Meaning	50	25.0	115	57.5	35	17.5	26.34	10.7
Sensory	52	26.0	100	50.0	48	24.0	26.69	12.6
Cognitive/Mood	52	26.0	106	53.0	42	21.0	32.14	11.2
Overall Fatigue	36	18.0	146	73.0	18	9.0	116.74	31.8

Anxiety and depression levels as measured by HAS among Study Subjects (N=200).

Mean ranks of the Total Symptom Distress Scale of the Study Subjects (N=200).

Table 3.

Relation between the Sociodemographic Characteristics of the Study Subjects and Their Mean Fatigue, Anxiety, and Depression Scores (N=200).

Variables	Anxiety				Depression				Fatigue
Variables	Normal	Borderline	Abnormal	p-value	Normal	Borderline	Abnormal	p-value	Normal	Borderline	Abnormal	p-value
Age (years)				0.50 FET				0.34				0.98
18-30	1	9	23		13	5	15		7	23	3
30-50	2	19	84		59	15	31		18	78	9
≥50	3	9	50		36	10	16		11	45	6
Gender				0.38 FET				0.01*				0.53
Male	3	14	80		47	22	28		17	69	11
Female	3	23	77		61	8	34		19	77	7
Working Status				0.58 FET				0.64				0.78
Working	3	18	61		46	10	26		15	61	6
Not working	3	19	96		62	20	36		21	85	12
Marital status				0.09 FET				0.40				0.94
Single	1	12	23		15	5	16		8	25	3
Married	2	15	87		60	16	28		17	78	9
Widow/divorce	3	10	47		33	9	18		11	43	6
Level of Education				0.25 FET				0.87				0.72 FET
Primary	3	5	53		34	10	17		8	45	8
Secondary	2	19	76		51	16	30		18	72	7
Bachelor	2	7	29		21	3	14		9	26	3
Postgraduate	0	0	4		2	1	1		1	3	0
History of the Hemodialysis,years				0.22 FET				0.17				0.52 FET
< 1	0	9	40		20	13	16		8	35	6
1 to < 5	0	13	49		38	5	19		9	48	5
5 to < 10	4	11	49		36	8	20		15	46	3
≥ 10	2	4	19		14	4	7		4	17	4
No of dialysis sessions/Week				0.17 FET				0.38				0.69
Two	0	4	33		23	6	8		5	28	4
Three	6	33	124		85	24	54		31	118	14
Duration of hemodialysis sessions, hours				0.77 FET				0.35 FET				0.88 FET
< 3	0	2	6		5	2	1		2	6	0
3	1	5	35		26	3	12		3	31	3
4	5	30	116		77	25	49		27	109	15

1* Note:. Statistically Significant (P < 0.05); FET: Fisher Exact Test.

Table 4.

Pearson Correlation between study variables (N=200).

Variables	Fatigue	Anxiety	Depression	Overall symptom distress	Ability to manage symptoms
Hemodialysis session frequency
Pearson correlation	–0.039	–0.193	0.031	-0.078	-0.027
P-value	0.579	0.006**	0.66	0.274	0.704
Fatigue
Pearson correlation		0.287	0.148	0.325	-0.21
P-value		< 0.001**	0.036*	< 0.001**	0.003**
Anxiety
Pearson correlation			0.356	0.422	–0.273
P-value			< 0.001**	< 0.001**	< 0.001**
Depression
Pearson correlation				0.212	0.111
P-value				0.003**	0.117
Overall symptom distress
Pearson correlation					–0.436
P-value					< 0.001**

2* Note: Statistically Significant (P <0.05);

3** Statistically Highly Significant (P <0.01)

Table 5.

Multiple linear regression model of psychological factors predicting fatigue (N = 200).

Items	Unstandardized coefficient		Standardized coefficient	t	P value
Items	B	Sth. Error	B	t	P value
Constant	34.646	17.063		2.031	0.044
Total anxiety	3.264	0.879	0.274	3.716	<0.001**
Total depression	1.913	0.426	0.305	4.489	<0.001**
Overall symptom distress	6.155	1.873	0.248	3.285	0.001**
Ability to manage symptoms	–1.163	1.337	–0.062	–0.869	0.386
ANOVA
Model	Df			F
Regression	4			13.527	<0.001**

4 Note: Dependent variable: total fatigue score;

5* Significant at P <0.05;

6** Highly significant at P <0.01.

References

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Articles in this issue

DOI: https://doi.org/10.2478/fon-2025-0040 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368

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Language: English

Page range: 365 - 373

Submitted on: Jul 3, 2024

Accepted on: Sep 18, 2024

Published on: Sep 25, 2025

Published by: Shanxi Medical Periodical Press

In partnership with: Paradigm Publishing Services

Keywords:

anxiety,

fatigue,

Related subjects:

Assistive professions, nursing

© 2025 Bahia Galal Abd Elrazik Siam, Wafaa G. M. Ali, Mohamed E. H. Elzeky, Eman H. Y. Heggy, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 12 (2025): Issue 3 (September 2025)

Factors predicting fatigue among patients undergoing hemodialysis

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