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Factors predicting fatigue among patients undergoing hemodialysis Cover

Factors predicting fatigue among patients undergoing hemodialysis

Open Access
|Sep 2025

Figures & Tables

Figure 1.

Anxiety and depression levels as measured by HAS among Study Subjects (N=200).
Anxiety and depression levels as measured by HAS among Study Subjects (N=200).

Figure 2.

Mean ranks of the Total Symptom Distress Scale of the Study Subjects (N=200).
Mean ranks of the Total Symptom Distress Scale of the Study Subjects (N=200).

Fatigue levels among study subjects as measured by the Piper Fatigue Scale (N=200)_

Piper Fatigue Scale Sub-dimensionsMildModerateSeverMeanSD
N%N%N%
Behavioral/Severity136.516281.02512.534.699.9
Affective Meaning5025.011557.53517.526.3410.7
Sensory5226.010050.04824.026.6912.6
Cognitive/Mood5226.010653.04221.032.1411.2
Overall Fatigue3618.014673.0189.0116.7431.8

Pearson Correlation between study variables (N=200)_

VariablesFatigueAnxietyDepressionOverall symptom distressAbility to manage symptoms
Hemodialysis session frequency
  Pearson correlation–0.039–0.1930.031-0.078-0.027
  P-value0.5790.006**0.660.2740.704
Fatigue
  Pearson correlation 0.2870.1480.325-0.21
  P-value < 0.001**0.036*< 0.001**0.003**
Anxiety
  Pearson correlation 0.3560.422–0.273
  P-value < 0.001**< 0.001**< 0.001**
Depression
  Pearson correlation 0.2120.111
  P-value 0.003**0.117
Overall symptom distress
  Pearson correlation –0.436
  P-value < 0.001**

Multiple linear regression model of psychological factors predicting fatigue (N = 200)_

ItemsUnstandardized coefficientStandardized coefficienttP value
BSth. ErrorB
Constant34.64617.063 2.0310.044
Total anxiety3.2640.8790.2743.716<0.001**
Total depression1.9130.4260.3054.489<0.001**
Overall symptom distress6.1551.8730.2483.2850.001**
Ability to manage symptoms–1.1631.337–0.062–0.8690.386
ANOVA
ModelDf F
Regression4 13.527<0.001**

Sociodemographic Characteristics of the Study Subjects (N=200)_

VariablesN%
Age (years)
  18-303316.5
  30-5010552.5
  ≥ 506231.0
Gender
  Male9748.5
  Female10351.5
Working Status
  Working8241.0
  Not working11859.0
Marital status
  Single3618.0
  Married10452.0
  Widow/divorce6030.0
Level of Education
  Primary6130.5
  Secondary9748.5
  Bachelor3819.0
  Postgraduate42.0
History of hemodialysis, years
  < 14924.5
  1 to < 56231.0
  5 to < 106432.0
  ≥ 102512.5
Frequency of dialysis sessions/Week
  Two3718.5
  Three16381.5
Duration of hemodialysis sessions, hours
  < 382.0
  34120.5
  415175.5

Relation between the Sociodemographic Characteristics of the Study Subjects and Their Mean Fatigue, Anxiety, and Depression Scores (N=200)_

VariablesAnxietyDepressionFatigue
NormalBorderlineAbnormalp-valueNormalBorderlineAbnormalp-valueNormalBorderlineAbnormalp-value
Age (years) 0.50 FET 0.34 0.98
  18-301923 13515 7233
  30-5021984 591531 18789
  ≥503950 361016 11456
Gender 0.38 FET 0.01* 0.53
  Male31480 472228 176911
  Female32377 61834 19777
Working Status 0.58 FET 0.64 0.78
  Working31861 461026 15616
  Not working31996 622036 218512
Marital status 0.09 FET 0.40 0.94
  Single11223 15516 8253
  Married21587 601628 17789
  Widow/divorce31047 33918 11436
Level of Education 0.25 FET 0.87 0.72 FET
  Primary3553 341017 8458
  Secondary21976 511630 18727
  Bachelor2729 21314 9263
  Postgraduate004 211 130
History of the Hemodialysis,years 0.22 FET 0.17 0.52 FET
  < 10940 201316 8356
  1 to < 501349 38519 9485
  5 to < 1041149 36820 15463
  ≥ 102419 1447 4174
No of dialysis sessions/Week 0.17 FET 0.38 0.69
  Two0433 2368 5284
  Three633124 852454 3111814
Duration of hemodialysis sessions, hours 0.77 FET 0.35 FET 0.88 FET
  < 3026 521 260
  31535 26312 3313
  4530116 772549 2710915
DOI: https://doi.org/10.2478/fon-2025-0040 | Journal eISSN: 2544-8994 | Journal ISSN: 2097-5368
Language: English
Page range: 365 - 373
Submitted on: Jul 3, 2024
|
Accepted on: Sep 18, 2024
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Published on: Sep 25, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Bahia Galal Abd Elrazik Siam, Wafaa G. M. Ali, Mohamed E. H. Elzeky, Eman H. Y. Heggy, published by Shanxi Medical Periodical Press
This work is licensed under the Creative Commons Attribution 4.0 License.