Published definitions of MS in pediatrics_
| Risk factors | de Ferranti et al.7 | Cook et al.9 | Cruz et al.12 |
|---|---|---|---|
| Abdominal obesity | >75 percentile | ≥90 percentile | ≥90 percentile |
| HDL-C | Female <50 mg/dL; male <45 mg/dL | ≤40 mg/dL | ≥10 percentile |
| Triglycerides | ≥100 mg/dL | ≥110 mg/dL | ≥90 percentile |
| Fasting glucose | ≥110 mg/dL | ≥110 mg/dL | IGT:ADA criterion |
| Blood pressure | >90 percentile | >90 percentile | >90 percentile |
NCEP-ATP III definition of MS in adults_
| Items | All | Female | Male |
|---|---|---|---|
| Central obesity | Waist ≥102 cm | Waist ≥88 cm | |
| Blood pressure | Systolic ≥130 mmHg; Diastolic ≥85 mmHg | ||
| Triglycerides | ≥1.7 mmol/L | ≥1.7 mmol/L | |
| HDL-C | <1.3 mmol/L | <1.0 mmol/L | |
| Fasting glucose | ≥6.1 mmol/L | ≥6.1 mmol/L |
IDF definition of MS in adolescents and children
| Items | Age group | ||
|---|---|---|---|
| 6–10 years | 10–16 years | >16 years | |
| Obesity (WC) | ≥90 percentile | ≥90 percentile (or adult cutoff) | Using adult criteria |
| Triglycerides | MS cannot be diagnosed | ≥150 mg/dL | Using adult criteria |
| HDL-C | MS cannot be diagnosed | <40 mg/dL | Using adult criteria |
| Blood pressure | MS cannot be diagnosed | Systolic: ≥130 mmHg; diastolic: ≥85 mmHg | Using adult criteria |
| Glucose | MS cannot be diagnosed | OGTE: ≥5.6 mmol/L; or known type 2 diabetes | Using adult criteria |