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Lung cancer with thyroid and colon metastases: a report of two cases Cover

Lung cancer with thyroid and colon metastases: a report of two cases

Forum of Clinical Oncology
Volume 14 (2023): Issue 3 (December 2023)
By: Maha Saif,  Manar Hamed,  Wagdi Elkashef,  Dina Abdallah Ibrahim,  Heba Sheta,  Reem Khaled,  Mohamed Ezzat,  Omar Hamdy and  Shadi Awny  
Open Access
|Jun 2024

Figures & Tables

Figure 1:

Chest computed tomography (CT) scan: Speculated soft tissue mass seen on the left main bronchus, measuring about 6.1 × 5.2 cm (measured lesion) and associated with subcarinal ln and minimal pleural effusion.
Chest computed tomography (CT) scan: Speculated soft tissue mass seen on the left main bronchus, measuring about 6.1 × 5.2 cm (measured lesion) and associated with subcarinal ln and minimal pleural effusion.

Figure 2:

Microscopic examination. (A) (Hematoxylin and eosin; ×40). Moderately differentiated adenocarcinoma infiltrates the colonic wall. (B) (CK7 immunohistochemistry; ×40), diffuse positive. (C) (TTF-1 immunohistochemistry; ×40), diffuse positive. (D) (Napsin A immunohistochemistry; ×40), diffuse positive. (E) (CK20 immunohistochemistry; ×40), negative reaction. (F) (CDX2 immunohistochemistry; ×40), negative reaction.
Microscopic examination. (A) (Hematoxylin and eosin; ×40). Moderately differentiated adenocarcinoma infiltrates the colonic wall. (B) (CK7 immunohistochemistry; ×40), diffuse positive. (C) (TTF-1 immunohistochemistry; ×40), diffuse positive. (D) (Napsin A immunohistochemistry; ×40), diffuse positive. (E) (CK20 immunohistochemistry; ×40), negative reaction. (F) (CDX2 immunohistochemistry; ×40), negative reaction.

Figure 3:

Microscopic examination. (A) (Hematoxylin and eosin; ×20). Photomicrograph that shows infiltration of thyroid gland tissue by malignant tumoral proliferation formed of malignant acini lined by multiple layers of malignant epithelial cells with moderate degree atypia and abundant pale eosinophilic to clear cytoplasm (B) (Napsin A immunohistochemistry; ×20), diffuse positive with negative reaction of the surrounding thyroid tissue. (C) (Thyroglobulin immunohistochemistry; ×10), malignant acini that show negative reaction for thyroglobulin with the positive reaction of the surrounding thyroid tissue (internal control). (D) (×10), Malignant deposits of the cervical lymph node by the same tumor tissue with a small rim of lymphoid tissue on the periphery. (E) (Napsin A immunohistochemistry; ×20), diffuse positive reaction. (F) (Thyroglobulin immunohistochemistry; ×20), negative reaction.
Microscopic examination. (A) (Hematoxylin and eosin; ×20). Photomicrograph that shows infiltration of thyroid gland tissue by malignant tumoral proliferation formed of malignant acini lined by multiple layers of malignant epithelial cells with moderate degree atypia and abundant pale eosinophilic to clear cytoplasm (B) (Napsin A immunohistochemistry; ×20), diffuse positive with negative reaction of the surrounding thyroid tissue. (C) (Thyroglobulin immunohistochemistry; ×10), malignant acini that show negative reaction for thyroglobulin with the positive reaction of the surrounding thyroid tissue (internal control). (D) (×10), Malignant deposits of the cervical lymph node by the same tumor tissue with a small rim of lymphoid tissue on the periphery. (E) (Napsin A immunohistochemistry; ×20), diffuse positive reaction. (F) (Thyroglobulin immunohistochemistry; ×20), negative reaction.
DOI: https://doi.org/10.2478/fco-2023-0023 | Journal eISSN: 1792-362X | Journal ISSN: 1792-345X
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Language: English
Page range: 43 - 50
Submitted on: Dec 1, 2023
Accepted on: May 4, 2024
Published on: Jun 27, 2024
Published by: Helenic Society of Medical Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
Keywords:
Lung cancer,
metastasis,
thyroid cancer,
intestinal obstruction,
case report
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology

© 2024 Maha Saif, Manar Hamed, Wagdi Elkashef, Dina Abdallah Ibrahim, Heba Sheta, Reem Khaled, Mohamed Ezzat, Omar Hamdy, Shadi Awny, published by Helenic Society of Medical Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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