Vitamin D3 as possible diagnostic marker of Eating Disorders

Vanessa La Bella; Giulia Gizzi; Elisabetta Albi; Michela Codini; Simonetta Marucci; Laura Dalla Ragione; Tommaso Beccari; Maria Rachele Ceccarini

doi:10.2478/ebtj-2021-0005

Figures & Tables

Different diagnoses of Eating Disorders. Percentage distribution of different subtypes of Eating Disorders in a population of 28 female patients. AN-RES (restrictive-type anorexia nervosa) in black, AN-PUR (purging-type anorexia nervosa) in dark grey, BN (bulimia nervosa) in light grey, and OSFED (other specified feeding or eating disorder) in white.

Patients with Eating Disorders divided by age. While 79% were over 14 years old, 21% were under 14 years old.

Percentage of patients with irregular blood count and procedure divided by type of EDs. AN-RES, restrictive-type anorexia nervosa, AN-PUR, purging-type anorexia nervosa, BN, bulimia nervosa, OSFED, other specified feeding or eating disorder.

Statistical analysis using non-parametric Kruskal-Wallis: a) leukocytes levels and EDs types (number 1 CTR, number 2 AN-RES, number 3 AN-PUR, number 4 BN and number 5 OSFED) b) erythrocytes levels and EDs types (number 1 CTR, number 2 AN-RES, number 3 AN-PUR, number 4 BN and number 5 OSFED), c) Pairwise Comparison to compare leukocytes levels and EDs types in pairs (significant correlation in yellow lines) d) Pairwise Comparison to compare erythrocytes levels and EDs types in pairs (significant correlation in yellow lines).

Percentage of patients with hypoglycemia and divided by type of EDs. AN-RES, restrictive-type anorexia nervosa, AN-PUR, purging-type anorexia nervosa, BN, bulimia nervosa, OSFED, other specified feeding or eating disorder.

Percentage of patients with hypercholesterolemia divided by type of EDs. AN-RES, restrictive-type anorexia nervosa, AN-PUR, purging-type anorexia nervosa, BN, bulimia nervosa, OSFED, other specified feeding or eating disorder.

Vitamin D3 values in adults patients divided by type of EDs. AN-RES, restrictive-type anorexia nervosa, AN-PUR, purging-type anorexia nervosa, BN, bulimia nervosa, OSFED, other specified feeding or eating disorder.

Vitamin D3 values in “girls” patients divided by type of Eating Disorders Only AN-RES, restrictive-type anorexia nervosa and OSFED, other specified feeding or eating disorder.

Statistical analysis using non-parametric Kruskal-Wallis: a) Vitamin D3 levels and EDs types (number 1 CTR, number 2 AN-RES, number 3 AN-PUR, number 4 BN and number 5 OSFED) b) Vitamin D3 levels and EDs types in different age groups (number 1 CTR<14, number 2 CTR>14, number 3 AN-RES<14, number 4 AN-RES>14, number 5 AN-PUR, number 6 BN and number 7 OSFED<14, number 8 OSFED>14), c) Pairwise Comparison to compare EDs types in pairs (significant correlation in yellow lines) d) Pairwise Comparison to compare EDs types in different age groups in pairs (significant correlation in yellow lines).

Sociodemographic characteristics (age) and clinical characteristics (BMI, clinical manifestations in the skin, muscle and genitourinary tract) of all the patients in the study according to type of EDs_

N°	Diagnoses	Age	BMI	Skin	Muscle	Genitourinary
1	AN-RES	11	14,2	pale-dehydrated	hypotrophic	no menarche
2	OSFED	11	14,1	hypotrophic	normotrophic-normotonic	secondary amenorrhea
3	AN-RES	12	15,1	hypertrophic-lanugo	hypotrophic	no menarche
4	AN-RES	12	15,4	pale-lanugo	hypotrophic-hypotonic	secondary amenorrhea
5	AN-RES	12	15,6	hypertrophic-lanugo	hypotrophic	secondary amenorrhea
6	AN-RES	12	17,2	normal	normotrophic-normotonic	no menarche
7	AN-RES	15	13,8	pale-normohydrated	normotrophic-normotonic	secondary amenorrhea
8	AN-RES	15	14,4	pale-lanugo	hypotonic	primary amenorrhea
9	AN-PUR	16	14,3	normal	hypotonic	regular menstrual cycle
10	AN-RES	16	12,8	pale-dehydrated	hypotrophic	secondary amenorrhea
11	AN-RES	16	13,2	pale-dehydrated	hypotrophic-hypotonic	secondary amenorrhea
12	AN-RES	16	15,1	hypotrophic	hypotrophic	primary amenorrhea
13	AN-RES	16	15,2	hypotrophic	hypotrophic	secondary amenorrhea
14	AN-PUR	17	16,2	pale-lanugo	hypotrophic	secondary amenorrhea
15	AN-RES	19	13,5	pale-dehydrated	hypotrophic-hypotonic	secondary amenorrhea
16	AN-RES	19	13,6	normal	normotrophic-normotonic	secondary amenorrhea
17	AN-RES	19	13,7	hypotrophic-lanugo	hypotrophic-hypotonic	secondary amenorrhea
18	AN-RES	19	15,2	hypotrophic-lanugo	hypotrophic	regular menstrual cycle
19	AN-RES	20	14,7	normal	hypotrophic	secondary amenorrhea
20	AN-RES	20	15,1	pale-lanugo	hypotrophic-hypotonic	secondary amenorrhea
21	OSFED	23	17,1	normal	normotrophic-normotonic	regular menstrual cycle
22	AN-PUR	24	14,2	hypotrophic-lanugo	hypotrophic	secondary amenorrhea
23	AN-RES	29	15,1	cyanosis	hypotrophic-hypotonic	secondary amenorrhea
24	BN	29	15,7	pale-dehydrated	hypotrophic-hypotonic	secondary amenorrhea
25	BN	29	23,3	normal	hypotonic (Bechet syndrome)	secondary amenorrhea
26	AN-PUR	32	14,6	normal	hypotrophic	secondary amenorrhea
27	AN-PUR	32	16,0	pale-dehydrated	normotrophic-normotonic	secondary amenorrhea
28	OSFED	50	23,3	normal	normotrophic-normotonic	regular menstrual cycle

Vitamin D3 as possible diagnostic marker of Eating Disorders

Figures & Tables

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Sociodemographic characteristics (age) and clinical characteristics (BMI, clinical manifestations in the skin, muscle and genitourinary tract) of all the patients in the study according to type of EDs_

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