Trends in Pancreatic Cancer Mortality in Serbia: A Joinpoint Regression Analysis

Year	Total			Men			Women
Year	N	Crude rate	ASR^a	N	Crude rate	ASR^a	N	Crude rate	ASR^a
2000	747	9.94	5.30	401	10.97	6.48	346	8.96	4.28
2001	772	10.29	5.34	445	12.20	7.04	327	8.48	3.96
2002	835	11.13	5.72	466	12.78	7.22	369	9.58	4.49
2003	855	11.43	5.87	451	12.40	6.98	404	10.51	4.88
2004	852	11.42	5.70	476	13.12	7.32	376	9.81	4.29
2005	988	13.32	6.61	518	14.32	8.07	470	6.25	3.11
2006	910	12.28	6.11	520	14.43	7.99	390	10.24	4.54
2007	966	13.09	6.18	491	13.68	7.42	475	12.52	5.13
2008	1034	14.07	6.60	561	15.70	8.29	473	12.53	5.17
2009	1020	13.03	6.49	546	15.34	8.19	474	12.60	5.01
2010	1088	14.92	7.06	566	15.96	9.51	522	13.94	5.78
2011	1055	14.58	6.73	570	16.18	8.32	485	13.06	5.43
2012	1099	15.26	6.65	573	16.34	8.04	526	14.24	5.46
2013	1070	14.93	6.56	585	16.76	8.24	485	13.19	5.12
2014	1056	14.81	6.41	573	16.50	7.99	483	13.20	5.09
2015	1134	15.98	6.89	618	17.89	8.44	516	14.18	5.61
2016	1151	16.31	6.83	599	17.42	8.15	552	15.25	5.81
2017	1156	16.47	6.77	619	18.10	8.35	537	14.91	5.44
2018	1168	16.73	6.98	615	18.08	8.41	553	15.44	5.79
2019	1206	17.36	7.14	640	18.91	8.69	566	15.89	5.80
2020	1169	16.94	6.81	625	18.60	8.46	544	15.37	5.39
2021	1157	16.93	6.76	595	17.88	7.97	562	16.02	5.74
Overall	22488	14.15	6.43	12053	15.62	8.24	10435	12.55	5.06

Trends of age-standardized pancreatic cancer mortality rates in Serbia by sex, in the period 2000–2021.

Distribution of pancreatic cancer mortality by age groups in Serbia, 2000 – 2021.

Trend in mortality of pancreatic cancer in Serbia, 2000 – 2021.

Table 2.

Joinpoint regression analysis^* of pancreatic cancer mortality by age in Serbia, 2000 – 2021.

	Total		Men		Women
	ASR±SD	AAPC^a (95% CI^b)	ASR±SD	AAPC^a (95% CI^b)	ASR±SD	AAPC^a (95% CI^b)
25 – 29	0.2±0.2		0.1±0.2		0.2±0.3
30 – 34	0.3±0.3		0.3±0.4		0.3±0.5
35 – 39	0.4±0.4	−0.9 (−4.5–2.9)	1.2±0.7		0.3±0.5
40 – 44	2.1±0.6	−1.3 (−3.6–1.2)	3.1±1.5	−1.5 (−4.3–1.5)	1.4±0.7
45 – 49	5.01±1.2	0.4 (−1.4–2.4)	6.3±2.0	−0.5 (−2.5–1.6)	3.9±1.8	2.1 (−2.4–7.1)
50 – 54	10.4±1.2	0.1 (−0.8–0.9)	13.8±4.2	−0.1 (−1.9–1.7)	7.8±1.5	0.5 (−1.2–2.3)
55 – 59	18.7±2.1	0.1 (−0.8–1.1)	24.5±3.9	−0.7 (−1.9–0.5)	13.3±2.4	1.9^* (0.6–3.2)
60 – 64	27.8±3.0	1.2^* (0.5–1.8)	35.2±5.1	1.1^* (0.1–2.2)	20.7±4.1	1.7 (−0.2–3.7)
65 – 69	40.0±5.5	1.7^* (1.1–2.4)	50.6±7.4	1.^* (1.0–2.5)	30.2±5.8	2.1^* (0.6–3.7)
70 – 74	52.2±6.1	1.6^* (0.6–2.6)	63.5±9.8	1.6^* (0.6–2.6)	42.9±6.6	0.9^* (0.01–1.8)
75 – 79	62.1±9.4	2.5^* (1.2–3.7)	71.3±14.5	2.1^* (0.6–3.6)	53.7±9.0	2.9^* (0.3–3.6)
80 – 84	70.4±10.0	1.7^* (0.7–2.8)	77.9±18.1	1.5 (−1.1–4.3)	65.2±12.2	2.1^* (0.7–3.4)
85+	63.3±11.4	3.1^* (1.6–4.5)	68.2±22.9		57.9±13.3	4.4^* (2.1–6.4)

a AAPC – Average Annual Percent Change

b CI – Confidence Interval

* Statistically significant trend

References

Authors

Metrics

Articles in this issue

DOI: https://doi.org/10.2478/eabr-2025-0007 | Journal eISSN: 2956-2090 (formerly 2335-075X, 2956-0454) | Journal ISSN: 2956-0454 (formerly 1820-8665)

Journal RSS Feed

Language: English

Page range: 353 - 360

Submitted on: Apr 4, 2025

Accepted on: May 8, 2025

Published on: Aug 7, 2025

Published by: University of Kragujevac, Faculty of Medical Sciences

In partnership with: Paradigm Publishing Services

Keywords:

Pancreatic cancer,

age-standardized rates,

mortality trend,

joinpoint analysis

UDC:

616.37-006.6-036.8(497.11)"2000/2021"

Related subjects:

Medicine,

Clinical medicine,

Clinical medicine, other

© 2025 Sanja Ilic, Filip Dzudovic, Jovana Radovanovic, Viktor Selakovic, Emilija Subanovic, Natalija Djurovic, Dragana Andric, Zorana Babic, Svetlana Vukosavljevic, Maja Mirocevic Rotolo, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 26 (2025): Issue 4 (December 2025)

Trends in Pancreatic Cancer Mortality in Serbia: A Joinpoint Regression Analysis

Figures & Tables

Table 1.

Figure 1.

Figure 2.

Figure 3.

Table 2.

Paradigm

My account