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Methodology Differences Impacting Prevalence Estimates of Youth Use of Electronic Nicotine Delivery Systems (ENDS) across Waves 5–7 of the Population Assessment of Tobacco and Health Cover

Methodology Differences Impacting Prevalence Estimates of Youth Use of Electronic Nicotine Delivery Systems (ENDS) across Waves 5–7 of the Population Assessment of Tobacco and Health

Open Access
|Sep 2026

Figures & Tables

Table 1.

Methodology differences between PATH Waves 5–7.

Wave 5Wave 5.5Wave 6Wave 7
Dates of administrationDec 1, 2018 – Nov 30, 2019July 3, 2020 – Dec 31, 2020Mar 1, 2021 – Nov 30, 2021Jan 6, 2022 – April 2, 2023
Survey mode: self-administered100%0%33.9%95.1%
Survey mode: telephone interview0%100%66.1%2.8%
Survey mode: Web interview───3.1%
Age range12–17Not analyzed14–1712–17
Full sample (N)11,976Not analyzed5,58510,650
Comparable across waves (N). Age 14–17 AND self-administered8,797Not analyzed1,6166,829
Not comparable across waves (N). Ages 12–13 OR telephone OR web survey3,179Not analyzed3,9693,821

[i] Note: Wave 5.5 was not analyzed in detail due to incomparability with other waves (i.e., 0% self-administered).

Figure 1.

Youth ENDS use prevalence and patterns of use, PATH Waves 5–7.

Table 2.

Usual/last-used ENDS brand, naïve analysis and comparable-subgroup analysis, PATH Waves 5–7.

Wave 5 (∼2019)Wave 6 (∼2021)Wave 7 (∼2022)p-value c,d (W5→7)p-value c,d (W6→7)
Naïve analysis aNo regular brand62.4%45.3%44.2%NA eNA
Naïve analysisMost common named brands
  • JUUL: 23.9%

  • Blu: 3.0%

  • SMOK: 1.8%

  • E-Swisher: 1.5%

  • Hyde: 10.0%

  • Vuse: 7.8%

  • JUUL: 6.5%

  • Puff: 9.3%

  • Hyde: 12.1%

  • Vuse: 6.1%

  • JUUL: 4.8%

  • Puff: 4.8%

  • Hyde: NA

  • Vuse: < 0.0001

  • JUUL: < 0.0001

  • Puff: NA

  • Hyde: 0.4041

  • Vuse: 0.2746

  • JUUL: 0.2924

  • Puff: 0.0126

Naïve analysisAll other listed brands1.9%4.1%5.6%NANA
Naïve analysisOther brand (not listed)3.2%11.6%10.8%< 0.00010.6954
Comparable subgroup bNo regular brand62.7%51.3%43.2%NANA
Comparable subgroupMost common named brands
  • JUUL: 23.7%

  • Blu: 3.1%

  • SMOK: 1.9%

  • Vuse: 0.4%

  • Hyde: 12.5%

  • Vuse: 9.4%

  • JUUL: 7.8%

  • Puff: 6.5%

  • Hyde: 13.0%

  • Vuse: 6.2%

  • JUUL: 5.5%

  • Puff: 5.1%

  • Hyde: NA

  • Vuse: < 0.0001

  • JUUL: < 0.0001

  • Puff: NA

  • Hyde: 0.8863

  • Vuse: 0.2338

  • JUUL: 0.3579

  • Puff: 0.5216

Comparable subgroupAll other listed brands1.8%2.4%5.1%NANA
Comparable subgroupOther brand (not listed)3.1%3.7%10.5%< 0.00010.0128

a Naïve analysis includes all youth participants, regardless of methodological differences between waves.

b Comparable subgroup analysis includes only youth participants aged 14–17 who self-administered the survey.

c An overall significance test was not possible due to different lists of most common brands across waves; thus, separate significance tests were performed for each brand vs. all others.

d The alpha level for brand comparisons is 0.01, using a Bonferroni correction for 5 tests.

e NA = not applicable

DOI: https://doi.org/10.2478/cttr-2026-0010 | Journal eISSN: 2719-9509 (formerly 1612-9237)
Language: English, French, German
Page range: 148 - 156
Submitted on: Dec 12, 2025
Accepted on: Jun 18, 2026
Published on: Sep 8, 2026
Published by: Beiträge zur Tabakforschung GmbH
In partnership with: Paradigm Publishing Services

© 2026 Arielle Selya, Michael J. Hannon, Sooyong Kim, Saul Shiffman, published by Beiträge zur Tabakforschung GmbH
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.