Figure 1.
Figure 2.
Figure 3.
Figure 4.
Figure 5.
Figure 6.
Figure 7.
Figure 8.
Test for precision, repeatability, and stability of the method_
| Target | Primary content (μg) | Additive quantity (μg) | Detection value (μg) | Average recovery (%) | Intraday RSD (%) | Interday RSD (%) |
|---|---|---|---|---|---|---|
| Nicotine | 3152 | 1500 | 4349.6 | 93.5 | 1.4 | 2.1 |
| 3000 | 6459.6 | 105 | 1.5 | 1.9 | ||
| 6000 | 9518.0 | 104 | 0.6 | 0.9 |
FTIR peak wavenumbers, assignments, and interpretations_
| Wavenumber (cm−1) | Assignment | Interpretation |
|---|---|---|
| 3381–3417 | –OH stretch vibration | Hydrogen bond reduction after crosslinking |
| 2923, 2848 | C–H stretch vibration | Aliphatic groups present in all materials |
| 1704 | C=O stretch vibration | Ester bond formation after crosslinking |
| 1645 | C=O stretch vibration | Carboxycarbonyl group |
| 1058, 1110 | C–O–C stretch and bend vibration | Cellulose backbone structure |
| 1031, 1163 | C–OH stretch vibration | Hydroxyl groups in cellulose |
Dissolution results of BC and 10% CA-BC at different nicotine contents_
| Material | Dissolution parameters | Nicotine content (%) | ||||
|---|---|---|---|---|---|---|
| 2.0 | 1.6 | 1 | 0.4 | 0.2 | ||
| 10% CA-BC | Dissolution degree (%) | 72.19 | 74.47 | 87.03 | 96.77 | 98.62 |
| Rate coefficient k (min−1) | 0.0345 | 0.0513 | 0.0536 | 0.0728 | 0.0905 | |
| Nicotine dissolution amount (μg) | 2165.7 | 1787.3 | 1305.5 | 580.6 | 295.9 | |
| BC | Dissolution degree (%) | 97.59 | 99.93 | 98.45 | 98.21 | 98.60 |
| Rate coefficient k (min−1) | 0.1546 | 0.1540 | 0.1236 | 0.1230 | 0.1467 | |
| Nicotine dissolution amount (μg) | 2927.7 | 2398.3 | 1476.8 | 589.3 | 295.8 | |
Model fitting results for dissolution profiles of BC and CA-BC aerogels_
| Parameters | BC | 1% CA-BC | 2% CA-BC | 5% CA-BC | 10% CA-BC | 20% CA-BC | 50% CA-BC | 100% CA-BC |
|---|---|---|---|---|---|---|---|---|
| FB/Fmax | 0.9987 | 0.9721 | 0.9253 | 0.9077 | 0.8444 | 0.8059 | 0.9281 | 0.9812 |
| k1 (min−1) | 0.0849 | 0.0538 | 0.0352 | 0.0280 | 0.0201 | 0.0213 | 0.0304 | 0.0720 |
| k2 (min−1) | 1.6163 | 0.8050 | 0.8014 | 0.7539 | 0.5947 | 0.5922 | 0.5858 | 0.8796 |
Operating curve regression equation, LODs, and LOQs of nicotine_
| Target | Linear range (μg × L−1) | Linear regression equation | R2 | LODs (ng × mL−1) | LOQs (ng × mL−1) |
|---|---|---|---|---|---|
| Nicotine | 9.1–182 | y = 0.002826 x- 0.0017 | 0.9999 | 95 | 316 |