Figure 1.
Figure 2.
Demographics_
| Characteristics | Loose MST n = 168 | Pouched MST n = 61 | Overall N = 229 |
|---|---|---|---|
| Mean age (SD), years | 37.6 (11.61) | 36.9 (10.75) | 37.4 (11.37) |
| Sex, n (%) | |||
| Male | 160 (95.2) | 54 (88.5) | 214 (93.4) |
| Female | 8 (4.8) | 7 (11.5) | 15 (6.6) |
| Race, n (%) | |||
| American Indian / Alaska native | 4 (2.4) | 1 (1.6) | 5 (2.2) |
| Asian | 1 (0.6) | — | 1 (0.4) |
| Black | 16 (9.5) | 9 (14.8) | 25 (10.9) |
| White | 145 (86.3) | 50 (82.0) | 195 (85.2) |
| Multiple | 2 (1.2) | 1 (1.6) | 3 (1.3) |
| Ethnicity, n (%) | |||
| Hispanic or Latino | 3 (1.8) | 3 (4.9) | 6 (2.6) |
| Not Hispanic or Latino | 165 (98.2) | 58 (95.1) | 223 (97.4) |
| Mean BMI (SD), kg/m2 | 29.3 (5.21) | 29.4 (4.97) | 29.3 (5.14) |
Summary statistics for product use behavior_ Data reflect a product use period of 16 h_
| Product use behavior | N | Mean | SD | Min | Median | Max |
|---|---|---|---|---|---|---|
| Loose MST | ||||||
| Average duration of use (min) | 168 | 73.95 | 33.884 | 15.6 | 70.48 | 188.00 |
| Average pinch mass (g) | 168 | 4.34 | 2.194 | 0.6 | 3.91 | 14.70 |
| Total number of use occasions/day | 168 | 6.50 | 2.240 | 2.0 | 6.00 | 14.00 |
| Total duration of use (min/day) | 168 | 451.6 | 203.040 | 103.0 | 434.50 | 1108.00 |
| Total weight used (g/day) | 168 | 28.14 | 18.222 | 3.5 | 24.47 | 132.70 |
| Pouched MST | ||||||
| Average duration of use (min) | 61 | 69.07 | 32.493 | 21.0 | 61.00 | 172.30 |
| Average number of pouches per use | 61 | 2.23 | 0.966 | 1.0 | 2.00 | 7.20 |
| Total number of use occasions/day | 61 | 6.00 | 2.640 | 1.0 | 5.00 | 15.00 |
| Total duration use (min/day) | 61 | 395.84 | 186.93 | 21.0 | 400.00 | 809.00 |
| Total number used/day | 61 | 13.3 | 7.380 | 2.0 | 12.00 | 36.00 |
Summary statistics for biomarkers of exposure_
| Biomarker of exposure | MST product format | N | Mean | SD | Min | Median | Max | Geometric mean | 95% CI of Geomean |
|---|---|---|---|---|---|---|---|---|---|
| Nicotine equivalents (mg/24 h) | Loose | 168 | 26.27 | 18.111 | 4.3 | 22.29 | 144.90 | 21.62 | 19.65–23.78 |
| Pouch | 61 | 20.40 | 11.807 | 3.5 | 17.19 | 52.60 | 17.46 | 15.08–20.23 | |
| NNN (ng/24 h) | Loose | 168 | 78.00 | 91.712 | 7.3 | 53.56 | 908.80 | 53.32 | 46.80–60.76 |
| Pouch | 61 | 61.99 | 43.714 | 1.9 | 44.17 | 183.93 | 46.44 | 37.62–57.33 |