References
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): Reference Products Used in Tobacco and Smoke Analyses; Tobacco J. Int. 2 (2013) 150–154. Available at: https://www.coresta.org/sites/default/files/pages/tji0213-p150-154-refproducts.pdf (accessed December 2020)
- Hamad, S.H., N.M. Johnson, M.E. Tefft, M.C. Brinkman, S.M. Gordon, P.I. Clark, and S.S. Buehler: Little Cigars vs 3R4F Cigarette: Physical Properties and HPHC Yields; Tob. Regul. Sci. 3 (2017) 459–478. DOI: 10.18001/TRS.3.4.7
- van der Toorn, M., K. Koshibu, W.K. Schlage, S. Majeed, P. Pospisil, J. Hoeng, and M.C. Peitsch: Comparison of Monoamine Oxidase Inhibition by Cigarettes and Modified Risk Tobacco Products; Toxicol. Rep. 6 (2019) 1206–1215. DOI: 10.1016/j.toxrep.2019.11.008
- Zanetti, F., A. Sewer, B. Titz, W.K. Schlage, A.R. Iskandar, A. Kondylis, P. Leroy, E. Guedj, K. Trivedi, A. Elamin, F. Martin, S. Frentzel, N.V. Ivanov, M.C. Peitsch, and J. Hoeng: Assessment of a 72-Hour Repeated Exposure to Swedish Snus Extract and Total Particulate Matter from 3R4F Cigarette Smoke on Gingival Organotypic Cultures; Food Chem. Toxicol. 125 (2019) 252–270. DOI: 10.1016/j.fct.2018.12.056
- Munakata, S., K. Ishimori, N. Kitamura, S. Ishikawa, Y. Takanami, and S. Ito: Oxidative Stress Responses in Human Bronchial Epithelial Cells Exposed to Cigarette Smoke and Vapor from Tobacco- and Nicotine-Containing Products; Regul. Toxicol. Pharmacol. 99 (2018) 122–128. DOI: 10.1016/j.yrtph.2018.09.009
- Takahashi, Y., Y. Kanemaru, T. Fukushima, K. Eguchi, S. Yoshida, J. Miller-Holt, and I. Jones: Chemical Analysis and In Vitro Toxicological Evaluation of Aerosol from a Novel Tobacco Vapor Product: A Comparison with Cigarette Smoke; Regul. Toxicol. Pharmacol. 92 (2018) 94–103. DOI: 10.1016/j.yrtph.2017.11.009
- Ito, S., M. Taylor, S. Mori, D. Thorne, T. Nishino, D. Breheny, M. Gaça, K. Yoshino, and C. Proctor: An Inter-Laboratory In Vitro Assessment of Cigarettes and Next Generation Nicotine Delivery Products; Toxicol. Lett. 315 (2019) 14–22. DOI: 10.1016/j.toxlet.2019.08.004
- Ishikawa, S., K. Matsumura, N. Kitamura, Y. Takanami, K. Ishimori, and S. Ito: Application of a Direct Aerosol Exposure System for the Assessment of Biological Effects of Cigarette Smoke and Novel Tobacco Product Vapor on Human Bronchial Epithelial Cultures; Regul. Toxicol. Pharmacol. 96 (2018) 85–93. DOI: 10.1016/j.yrtph.2018.05.004
- Phillips, B., E. Veljkovic, S. Boué, W.K. Schlage, G. Vuillaume, F. Martin, B. Titz, P. Leroy, A. Buettner, A. Elamin, A. Oviedo, M. Cabanski, H.D. León, E. Guedj, T. Schneider, M. Talikka, N.V. Ivanov, P. Vanscheeuwijck, M.C. Peitsch, and J. Hoeng: An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe−/− Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes; Toxicol. Sci. 149 (2016) 411–432. DOI: 10.1093/toxsci/kfv243
- Walczak, J., D. Malińska, K. Drabik, B. Michalska, M. Prill, S. Johne, K. Luettich, J. Szymański, M.C. Peitsch, J. Hoeng, J. Duszyński, M.R. Więckowski, M. van der Toorn, and J. Szczepanowska: Mitochondrial Network and Biogenesis in Response to Short and Long-Term Exposure of Human BEAS-2B Cells to Aerosol Extracts from the Tobacco Heating System 2.2; Cell Physiol. Biochem. 54 (2020) 230–251. DOI: 10.33594/000000216
- Rayner, R.E., P. Makena, G.L. Prasad, and E. Cormet-Boyaka: Cigarette and ENDS Preparations Differentially Regulate Ion Channels and Mucociliary Clearance in Primary Normal Human Bronchial 3D Cultures; Am. J. Physiol. Lung. Cell. Mol. Physiol. 317 (2019) L295–L302. DOI: 10.1152/ajplung.00096.2019
- Jaccard, G., D.T. Djoko, A. Korneliou, R. Stabbert, M. Belushkin, and M. Esposito: Mainstream Smoke Constituents and In Vitro Toxicity Comparative Analysis of 3R4F and 1R6F Reference Cigarettes; Toxicol. Rep. 6 (2019) 222–231. DOI: 10.1016/j.toxrep.2019.02.009
- International Organization for Standardization (ISO): ISO 3308:2012: Routine Analytical Cigarette-Smoking Machine – Definitions and Standard Conditions; ISO, Geneva, Switzerland, 2012.
- International Organization for Standardization (ISO): ISO 20778:2018: Cigarettes – Routine Analytical Cigarette Smoking Machine – Definitions and Standard Conditions with an Intense Smoking Regime; ISO, Geneva, Switzerland, 2018.
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): In Vitro Toxicity Testing Sub-Group: Technical Report: Rationale and Strategy for In Vitro Toxicity Testing of Combustible Tobacco Products; Ref. IVT-225-CTR; Available at: https://www.coresta.org/rationale-and-strategy-vitrot-toxi-city-testing-combustible-tobacco-products-32586.html (accessed December 2020)
- Pryor, W.A. and K. Stone: Oxidants in Cigarette Smoke. Radicals, Hydrogen Peroxide, Peroxynitrate, and Peroxynitrite; Ann. N. Y. Acad. Sci. 686 (1993) 12–27. DOI: 10.1111/j.1749-6632.1993.tb39148.x
- van der Vaart, H., D.S. Postma, W. Timens, and N.H. ten Hacken: Acute Effects of Cigarette Smoke on Inflammation and Oxidative Stress: A Review; Thorax. 59 (2004) 713–721. DOI: 10.1136/thx.2003.012468
- Sekine, T., T. Hirata, T. Mine, and Y. Fukano: Activation of Transcription Factors in Human Bronchial Epithelial Cells Exposed to Aqueous Extracts of Main-stream Cigarette Smoke In Vitro; Toxicol. Mech. Meth. 26 (2016) 22–31. DOI: 10.3109/15376516.2015.1123788
- College of Agriculture, Food and Environment: Center for Tobacco Reference Products: 3R4F CIGARETTES. 3R4F Composition: Preliminary Analysis. Available at: https://ctrp.uky.edu/products/gallery/Reference%20Cigarettes/detail/936 (accessed December 2020)
- College of Agriculture, Food and Environment: Center for Tobacco Reference Products: 1R6F CIGARETTES. 1R6F Composition: Preliminary Analysis. Available at: https://ctrp.uky.edu/products/gallery/Reference%20Cigarettes/detail/937 (accessed December 2020)
- International Organization for Standardization (ISO): ISO 3402:1999: Tobacco and Tobacco Products – Atmosphere for Conditioning and Testing; ISO, Geneva, Switzerland, 1999.
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): The CORESTA Unit (CU); Available at: https://www.coresta.org/coresta-unit-cu (accessed December 2020)
- International Organization for Standardization (ISO): ISO 4387:2019: Cigarettes – Determination of Total and Nicotine-Free Dry Particulate Matter Using a Routine Analytical Smoking Machine; ISO, Geneva, Switzerland, 2019.
- International Organization for Standardization (ISO): ISO 10315:2013: Cigarettes – Determination of Nicotine in Smoke Condensates – Gas-Chromatographic Method; ISO, Geneva, Switzerland, 2013.
- International Organization for Standardization (ISO): ISO 8454:2007/AMD 2:2019: Cigarettes – Determination of Carbon Monoxide in the Vapour Phase of Cigarette Smoke – NDIR Method – Amendment 2; ISO, Geneva, Switzerland, 2019.
- International Organization for Standardization (ISO): ISO 19290:2016: Cigarettes – Determination of Tobacco Specific Nitrosamines in Mainstream Cigarette Smoke – Method Using LC-MS/MS; ISO, Geneva, Switzerland, 2016.
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): CORESTA Recommended Method No. 74 – Determination of Selected Carbonyls in Mainstream Cigarette Smoke by High Performance Liquid Chromatography (HPLC) (2018). Available at: https://www.coresta.org/determination-selected-carbonyls-mainstream-cigarette-smoke-high-performance-liquid-chromatography (accessed December 2020)
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): CORESTA Recommended Method No. 70 – Determination of Selected Volatile Organic Compounds in the Mainstream Smoke of Cigarettes – Gas Chromatography-Mass Spectrometry Method (2018). Available at: https://www.coresta.org/determination-selected-volatile-organic-compounds-mainstream-smoke-cigarettes-gas-chromatography (accessed December 2020)
- Health Canada: Official Method T-107: Determination of Hydrogen Cyanide in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Health Canada: Official Method T-103: Determination of Benzo[a]pyrene in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): CORESTA Recommended Method No. 78 – Determination of Selected Phenolic Compounds in Mainstream Cigarette Smoke by HPLCFLD (2018). Available at: https://www.coresta.org/determination-selected-phenolic-compounds-mainstream-cigarette-smoke-hplc-fld-29201.html (accessed December 2020)
- Health Canada: Official Method T-101: Determination of Ammonia in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Health Canada Official Method T-110: Determination of Oxides of Nitrogen in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Health Canada: Official Method T-112: Determination of Pyridine, Quinoline, and Styrene in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Smith, C.J., G.L. Dooly, and S.C. Moldoveanu: New Technique Using Solid-Phase Extraction for the Analysis of Aromatic Amines in Mainstream Cigarette Smoke; J. Chromatogr. A. 991 (2003) 99–107. DOI: 10.1016/s0021-9673(03)00205-x
- Health Canada: Official Method T-108: Determination of Mercury in Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 1999.
- Organisation for Economic Co-operation and Development (OECD): OECD GUIDELINE FOR TESTING OF CHEMICALS: Test No. 471: Bacterial Reverse Mutation Test; OECD, Paris, France, 1997.
- Organisation for Economic Co-operation and Development (OECD): OECD GUIDELINE FOR TESTING OF CHEMICALS: Test No. 487: In Vitro Mammalian Cell Micronucleus Test; OECD, Paris, France, 2014.
- Health Canada: Official Method T-502: Neutral Red Uptake Assay for Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 2004.
- Oldham, M.J., H.J. Haussmann, W. Gomm, L.T. Rimmer, M.J. Morton, and W.J. McKinney Jr.: Discriminatory Power of Standard Toxicity Assays Used to Evaluate Ingredients Added to Cigarettes; Regul. Toxicol. Pharmacol. 62 (2012) 49–61. DOI: 10.1016/j.yrtph.2011.11.018
- Schaller, J.P., D. Keller, L. Poget, P. Pratte, E. Kaelin, D. McHugh, G. Cudazzo, D. Smart, A.R. Tricker, L. Gautier, M. Yerly, R.R. Pires, S.L. Bouhellec, D. Ghosh, I. Hofer, E. Garcia, P. Vanscheeuwijck, and S. Maeder: Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical Composition, Genotoxicity, Cytotoxicity, and Physical Properties of the Aerosol; Regul. Toxicol. Pharmacol. 81 (2016) S27–S47. DOI: 10.1016/j.yrtph.2016.10.001
- Thorne, D., D. Breheny, C. Proctor, and M. Gaca: Assessment of Novel Tobacco Heating Product THP1.0. Part 7: Comparative In Vitro Toxicological Evaluation; Regul. Toxicol. Pharmacol. 93 (2017) 71–83. DOI: 10.1016/j.yrtph.2017.08.017
- Cooperation Center for Scientific Research Relative to Tobacco (CORESTA): In Vitro Toxicity Testing of Tobacco Smoke Sub-Group: Technical Report: Ames Assay Proficiency Study; Ref. IVT-077-CTR. Available at: https://www.coresta.org/ames-assay-proficiency-study-29536.html (accessed December 2020)
- Health Canada: Official Method T-503: In Vitro Micro-nucleus Assay for Mainstream Tobacco Smoke; Health Canada, Ottawa, Canada, 2004.
- Robertson, M.L., D.A. Eastmond, and M.T. Smith: Two Benzene Metabolites, Catechol and Hydroquinone, Produce a Synergistic Induction of Micronuclei and Toxicity in Cultured Human Lymphocytes; Mutat. Res. 249 (1991) 201–209. DOI: 10.1016/0027-5107(91)90147-G
- Tewes. F.J., T.J. Meisgen, D.J. Veltel, E. Roemer, and G. Patskan: Toxicological Evaluation of an Electrically Heated Cigarette. Part 3: Genotoxicity and Cytotoxicity of Mainstream Smoke; J. Appl. Toxicol. 23 (2003) 341–348. DOI: 10.1002/jat.925
- Goel, R., Z.T. Bitzer, S.M. Reilly, J. Foulds, J. Muscat, R.J. Elias, and J.P. Richie Jr.: Influence of Smoking Puff Parameters and Tobacco Varieties on Free Radicals Yields in Cigarette Mainstream Smoke; Chem. Res. Toxicol. 31 (2018) 325–331. DOI: 10.1021/acs.chemrestox.8b00011