Figure 1.
Figure 2.
Figure 3.
CDS1 (CHEK2) expression public 23Q2 and drug sensitivity (PRISM repurposing primary screen)
| Compound | Pearson | Spearman | Slope | Intercept | p-value (linregress) |
|---|---|---|---|---|---|
| aminophylline | 0.127 | 0.131 | 3.78E-2 | −4.29E-1 | 2.69E-3 |
| levomepromazine | 0.125 | 0.124 | 2.94E-2 | −5.82E-2 | 3.26E-3 |
| chloropyramine | 0.117 | 0.127 | 7.68E-2 | −2.00E+0 | 6.23E-3 |
| chlorhexidine | 0.150 | 0.133 | 8.26E-2 | −8.63E-2 | 4.36E-4 |
| parbendazole | 0.123 | 0.124 | 1.21E-1 | −2.26E+0 | 3.81E-3 |
| bisacodyl | −0.217 | −0.190 | −7.49E-2 | 3.66E-1 | 2.76E-7 |
| anisomycin | 0.128 | 0.126 | 1.11E-1 | −3.16E+0 | 2.71E-3 |
| mepacrine | −0.141 | −0.131 | −4.70E-2 | 4.50E-1 | 1.02E-3 |
| trifluridine | 0.140 | 0.137 | 1.10E-1 | −1.21E+0 | 1.31E-3 |
The list of Chondrosarcoma cell lines
| Name of the cell lines | Diseases Subtype |
|---|---|
| CAL78 | Dedifferentiated Chondrosarcoma |
| CHSA0011 | Chondrosarcoma |
| CHSA0108 | Chondrosarcoma |
| CHSA8926 | Chondrosarcoma |
| CS1 | Chondrosarcoma |
| HEMCSS | Extraskeletal Myxoid Chondrosarcoma |
| OUMS27 | Chondrosarcoma |
| SW1353 | Chondrosarcoma |