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Cytotoxic effects of individual and binary combinations of zearalenone and ochratoxin a on liver Cover

Cytotoxic effects of individual and binary combinations of zearalenone and ochratoxin a on liver

By: D.E. Marin,  G. C. Pistol and  I. Taranu  
Open Access
|Oct 2020

References

  1. Alshannaq A, Yu JH. 2017. Occurrence, Toxicity, and Analysis of Major Mycotoxins in Food. Int J Environ Res Public Health 14(6).10.3390/ijerph14060632
  2. Bellver Soto J, Fernandez-Franzon M, Ruiz MJ, Juan-Garcia A. 2014. Presence of ochratoxin A (OTA) mycotoxin in alcoholic drinks from southern European countries: wine and beer. J Agric Food Chem 62(31):7643-51.10.1021/jf501737h
  3. Chou TC. 2006. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58(3):621-81.10.1124/pr.58.3.10
  4. Diekman MA, Green ML. 1992. Mycotoxins and reproduction in domestic livestock. J Anim Sci 70(5):1615-27.10.2527/1992.7051615x
  5. Kifer D, Jaksic D, Segvic Klaric M. 2020. Assessing the Effect of Mycotoxin Combinations: Which Mathematical Model Is (the Most) Appropriate? Toxins (Basel) 12(3).10.3390/toxins12030153
  6. Kuiper-Goodman T, Scott PM. 1989. Risk assessment of the mycotoxin ochratoxin A. Biomed Environ Sci 2(3):179-248.
  7. Kuiper-Goodman T, Scott PM, Watanabe H. 1987. Risk assessment of the mycotoxin zearalenone. Regul Toxicol Pharmacol 7(3):253-306.10.1016/0273-2300(87)90037-7
  8. Li Y, Wang TQ, Wu J, Zhang XL, Xu YY, Qian YZ. 2018. Multi-parameter analysis of combined hepatotoxicity induced by mycotoxin mixtures in HepG2 cells. World Mycotoxin Journal 11(2):225-235.10.3920/WMJ2017.2201
  9. Liew WP, Mohd-Redzwan S. 2018. Mycotoxin: Its Impact on Gut Health and Microbiota. Front Cell Infect Microbiol 8:60.10.3389/fcimb.2018.00060583442729535978
  10. Marin DE, Pistol GC, Bulgaru CV, Taranu I. 2019. Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites. Naunyn Schmiedebergs Arch Pharmacol 392(8):937-947.10.1007/s00210-019-01644-z30919009
  11. Monbaliu S, Van Poucke C, Detavernier Cl, Dumoulin F, Van De Velde M, Schoeters E, Van Dyck S, Averkieva O, Van Peteghem C, De Saeger S. 2010. Occurrence of Mycotoxins in Feed as Analyzed by a Multi-Mycotoxin LC-MS/MS Method. Journal of Agricultural and Food Chemistry 58(1):66-71.10.1021/jf903859z19994896
  12. Pazaiti A, Kontos M, Fentiman IS. 2012. ZEN and the art of breast health maintenance. Int J Clin Pract 66(1):28-36.10.1111/j.1742-1241.2011.02805.x22145580
  13. Shin HS, Lee HJ, Pyo MC, Ryu D, Lee KW. 2019. Ochratoxin A-Induced Hepatotoxicity through Phase I and Phase II Reactions Regulated by AhR in Liver Cells. Toxins (Basel) 11(7).10.3390/toxins11070377666948931261931
  14. Streit E, Schatzmayr G, Tassis P, Tzika E, Marin D, Taranu I, Tabuc C, Nicolau A, Aprodu I, Puel O and others. 2012. Current situation of mycotoxin contamination and co-occurrence in animal feed--focus on Europe. Toxins (Basel) 4(10):788-809.10.3390/toxins4100788349698923162698
  15. Torovic L, Trajkovic Pavlovic L, Popovic M. 2017. Ochratoxin A and aflatoxin B1 in breakfast cereals marketed in Serbia - occurrence and health risk characterisation. Food Addit Contam Part B Surveill 10(3):176-184.10.1080/19393210.2017.128535828112034
  16. Zheng N, Gao YN, Liu J, Wang HW, Wang JQ. 2018. Individual and combined cytotoxicity assessment of zearalenone with ochratoxin A or alpha-zearalenol by full factorial design. Food Sci Biotechnol 27(1):251-259.10.1007/s10068-017-0197-9604976230263747
  17. Zhu L, Zhang B, Dai Y, Li H, Xu W. 2017. A Review: Epigenetic Mechanism in Ochratoxin A Toxicity Studies. Toxins 9(4):113.10.3390/toxins9040113540818728333080
DOI: https://doi.org/10.2478/azibna-2020-0007 | Journal eISSN: 2344-4592 | Journal ISSN: 1016-4855
Language: English
Page range: 73 - 80
Published on: Oct 2, 2020
Published by: National Institute for Research-Development in Biology and Animal Nutrition
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2020 D.E. Marin, G. C. Pistol, I. Taranu, published by National Institute for Research-Development in Biology and Animal Nutrition
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.