Abstract
Current studies are focused on medicinal plants secondary metabolites as a source of new anticancer agents. The aim of this study was to evaluate in vitro influence of methanolic extracts of Achillea thracica Velen. from natural habitat, in vitro propagated and ex vitro established plants on tumor cells proliferation/viability. All extract tested (50 µg/ml for 24 hours) significantly inhibited SK-HEP-1 cell line proliferation/viability (Р ≤ 0.05). The inhibitory effect of ex vitro established plants was slightly weaker in comparison with A. thracica grown in its natural habitat. So, ex situ conservation of A. thracica enables an opportunity to explore its valuable phytochemicals.