Assessment of Antioxidant effect of the essential oil and methanol extract of Centaurea dimorpha Viv. aerial parts from Algeria.

Belkassam, Abdelwahab; Zellagui, Amar; Gherraf, Noureddine; Flamini, Guido; Cioni, Pier Luigi; Rebbas, Khellaf; Smaili, Tahar

doi:10.2478/asn-2019-0008

Abstract

The essential oils obtained by hydrodistillation of aerial parts of Centaurea dimorpha Viv. were analyzed by means of gas chromatography-mass spectrometry (GC-MS). The main constituents were Caryophyllene oxide (09.88%), limonene (5.73%), tetradecanoic acid (5.68%), spathulenol (5.44%), methyl hexadecanoate (4.45%), and α-pinene (03.08%). To our best knowledge this is the first study of essential oils from the aerial parts of Centaurea dimorpha growing in Algeria. Moreover the essential oil and methanolic extract were screened for their possible in vitro antioxidant activity by DPPH free radical-scavenging test. The findings showed that the percentage inhibition is 10.67 and 77.01 respectively at a concentration of 1mole/L.

References

[1] Quezel, P.; Santa, S., Nouvelle Flore de L’Algérie et des Régions Désertiques Méridionales. Editions Du Centre National de la Recherche Scientifique (C.N.R.S), France, Paris, 1963, Tome II. 663 p.
Search in Google Scholar Back to article
[2] Ozenda, P., Flore et végétation du Sahara. Edition, Centre National de la Recherche Scientifique (C.N.R.S), Paris, 1991. 453 p.10.1016/S0016-6995(06)80408-0
Search in Google Scholar Back to article
[3] Yayli, N.; Yasar, A.; Güleç, C.; Usta, A.; Kolayli, S.; Coskunçelebi.; Karaoglu, S., Composition and antimicrobial activity of essential oils from Centaurea sessilis and Centaurea armena, Phytochemistry, 2005,66, 1741-1745.10.1016/j.phytochem.2005.04.006
Search in Google Scholar Back to article
[4] Csupor, D.; Blazso, G.; Balogh, A.; Hohmann, J., The traditional Hungarian medicinal plant Centaurea sadleriana Janka accelerates wound healing in rats. Journal of Ethnopharmacology, 2010,127, 193-195.10.1016/j.jep.2009.09.049
Search in Google Scholar Back to article
[5] Zengin, G.; Cakmak,Y. S.; Guler, G.O.; Aktumsek, A., In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey, Food and Chemical Toxicology, 2010,48, 2638-2641.
Search in Google Scholar Back to article
[6] Köse, Y.B.; Iscan, G.; Demirci, B.; Baser, K.H.C. Celik, S., Antimicrobial activity of the essential oil of Centaurea aladagensis, Fitoterapia, 2007,78, 253-254.10.1016/j.fitote.2006.12.002
Search in Google Scholar Back to article
[7] Wei, H.X.; Gao,W.Y.; Tian, Y.K.; Guan, Y.K.; Huang, M.H.; Cheng, D.L., Neweudesmane sesquiterpene and thiophene derivatives from the roots of Rhaponticum uniflorum, Die Pharmazie, 1997,52, 245–247.10.1002/chin.199727193
Search in Google Scholar Back to article
[8] Akkol, E.K.; Arif, R.; Ergun, F.; Yesilada, E., Sesquiterpene lactones with antinoceptive and antipyretic activity from two Centaurea specirs, Journal of Ethnopharmacology, 2009,122, 210–215.10.1016/j.jep.2009.01.019
Search in Google Scholar Back to article
[9] Sepulveda, S.; Delhvi, S.; Koch, B.; Zilliken, F., Constituents of Centaurea chilensis, Fitoterapia, 1994,65, 88–89.
Search in Google Scholar Back to article
[10] Al-Easa, H.S.; Kamel, A.; Rızık, A.F., Flavonoids from Centaurea sinaica, Fitoterapia, 1992,63, 468–469.
Search in Google Scholar Back to article
[11] Vazquez, F.M.; Suarez, M.A.; Perez, A., Medicinal plants used in the Barros Area, Badajoz Province (Spain), Journal of Ethnopharmacology, 1997,55, 81-85.10.1016/S0378-8741(96)01491-2
Search in Google Scholar Back to article
[12] Ali, Y.E.; Omar, A.A.; Sarg, T.M.; Slatkin, D.J., Chemical constituents of Centaurea pallescens, Planta Medica, 1987,53, 503–504.10.1055/s-2006-962790
Search in Google Scholar Back to article
[13] Kamanzi, K.; Raynaud, J.; Voirin, B., The C-glycosyl flavonoids from flowers of Centaurea malitensis, Plantes Medicinal et Phytotherapie, 1983,17, 47–51.
Search in Google Scholar Back to article
[14] Gonzalez, A.G.; Darias, V.; Alonso, G.; Boada, J.N.; Feria, M., Cytostatic activity of sesquiterpene lactones from compositae of the Canary Island, Planta Medica, 1978,33, 356–359..10.1055/s-0028-1097391
Search in Google Scholar Back to article
[15] Gurbuz, I.; Yesilada, E., Evaluation of the anti-ulcerogenic effect of sesquiterpene lactones from Centaurea solstitialis L. ssp. solstitialis by using various in vivo and biochemical techniques, Journal of Ethnopharmacology,2007,112, 284–291.10.1016/j.jep.2007.03.009
Search in Google Scholar Back to article
[16] Koca, U.; Nahar, L.; Süntar, I. P.; Keles, H.; Yesilada, E.; Akkol, E. K., In vivo anti-inflammatory and wound healing activities of Centaurea iberica Trev. ex Spreng, Journal of Ethnopharmacology, 2009,126, 551-556.10.1016/j.jep.2009.08.017
Search in Google Scholar Back to article
[17] Rice-Evans, C.A.; Miller, N.J.; Bolwell, P.G.; Bramley, P.M.; Pridham, J.B., The relative antioxidant activities of plant derived polyphenolic flavonoids, Free Radical Research, 1995,22, 375–38310.3109/10715769509145649
Search in Google Scholar Back to article
[18] Masuda, T.; Yonemori, S.; Oyama, Y.; Takeda, Y.; Tanaka, T.; Andoh, T.; Shinohara, A.; Nakata, M., Evaluation of the antioxidant activity of environmental plants: Activity of the leaf extracts from seashore plants, Journal of Agriculture and Food Chemistry, 1999,47(4), 1749–1754.10.1021/jf980864s
Search in Google Scholar Back to article
[19] Viegi, L.; Vangelisti, R.; Cecotti, R.; Tava, A., Essential oil composition of some Centaurea Sp. (Asteraceae) from different Italian islands, Atti Soc. Tosc. Sci. Nat., Mem., Serie B, 2014, 121
Search in Google Scholar Back to article
[20] Tastan, P.; Fafal, T.; Tuzun, B. S.; Gonenc, T.; Demirci, B.; Kivcak, B., Composition of essential oil and fatty acids of Centaurea pichleri ssp. Pichleri, Int. J. Sec. Metabolite,2017, 4(3), 37-4210.21448/ijsm.356269
Search in Google Scholar Back to article
[21] Rosselli, S.; Bruno, M.; Maggio, A.; Raccuglia, R.A.; Bancheva, S.; Senatore, F.; Formisano, C., Essential oils from the aerial parts of Centaurea cuneifolia Sibth. & Sm. and C. euxina Velen., tow species growing wild in Bulgaria, Biochemical Systematics and Ecology, 2009,37, 426-431.10.1016/j.bse.2009.05.001
Search in Google Scholar Back to article
[22] Rosselli, S.; Bruno, M.; Maggio, A.; Raccuglia, R.A.; Bancheva, S.; Senatore, F.; Formisano, C., Essential oil composition of two endemic Centaurea species from Turkey, Centaurea mucronifera and Centaurea chrysantha, collected in the same habitat, Biochemical Systematics and Ecology, 2009,31, 1417-1425.10.1016/S0305-1978(03)00128-5
Search in Google Scholar Back to article
[23].Kilic, O., Essential oil compounds of three Centaurea L. taxa from Turkey and their chemotaxonomy. J. Medic. Plants Res.,2013, 7(19), 1344-1350.
Search in Google Scholar Back to article
[24] Davies., N.W., Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicone and Carbowax 20M phases, Journal of Chromatography, 1990,50, 1-2410.1016/S0021-9673(01)81487-4
Search in Google Scholar Back to article
[25] Zengin,Y.S.; Cakmak, G.O.; Guler, A.; Aktumsek, A., In vitro antioxidant capacities and fatty acid compositions of three Centaurea species collected from Central Anatolia region of Turkey, Food and Chemical Toxicology, 2010,48, 2638-2641.10.1016/j.fct.2010.06.033
Search in Google Scholar Back to article
[26] Louaar, S.; Zellagui, A.; Gherraf, N.; Medjroubi, K.; Derbre, S.; Seguin, E.; Laouer, H.; Akkal, S., Antiradical Activity of Flavonoids from the Algerian Native Plant: Centaurea microcarpa Coss. et Dur. Journal of Biologically Active Products from Nature TBAP,2014, 4 (3), 249 – 253.10.1080/22311866.2014.902754
Search in Google Scholar Back to article
[27] Marian, E.; Vicas, L. G.; Tunde, J.; Muresan, M.; Stan, R. L.; Sevastere, B. Z.; Diaconeasa, C.; Ionescu, A.; Hangan, C., Comparative Study on the biologic activity of Centaurea cyanus versus, Calendula officinalis, Farmacia, 2017, 65, 6.
Search in Google Scholar Back to article
[28]. Chougule, P.; Pawar, R.; Limaye, D.; Joshi, Y. M.; Kadam, V., In-Vitro Antioxidant Activity of Ethanolic Extract of Centaurea behen, Journal of Applied Pharmaceutical Science,2012,02 (04), 106-110.10.7324/JAPS.2012.2421
Search in Google Scholar Back to article
[29] Öa, E.-D.; Pekmez, M.B.; Bona, M.C.; Aras-Perk, A.C.; Arda, N., Total Phenolic Contents, Antioxidant Activities and Cytotoxicity of Three Centaurea Species: C. calcitrapa subsp. calcitrapa, C. ptosimopappa and C. spicata, Free Radicals and Antioxidants, 2011,1, (2), 31-3610.5530/ax.2011.2.7
Search in Google Scholar Back to article

Assessment of Antioxidant effect of the essential oil and methanol extract of Centaurea dimorpha Viv. aerial parts from Algeria.

Abstract

Paradigm

My account