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Fluoride ion emission, shear bond strength, and adhesive remnant index of calcium fluoride nanoparticles-containing orthodontic primer: an In Vitro study Cover

Fluoride ion emission, shear bond strength, and adhesive remnant index of calcium fluoride nanoparticles-containing orthodontic primer: an In Vitro study

Open Access
|Jun 2025

References

  1. Tufekci E, Dixon JS, Gunsolley J, Lindauer SJ. Prevalence of white spot lesions during orthodontic treatment with fixed appliances. Angle Orthod 2011;81:206–10.
  2. Buschang PH, Chastain D, Keylor CL, Crosby D, Julien KC. Incidence of white spot lesions among patients treated with clear aligners and traditional braces. Angle Orthod 2019;89:359–64.
  3. Willmot D, ed. White spot lesions after orthodontic treatment. Seminars in Orthodontics.■: Elsevier; 2008.
  4. Sardana D, Schwendicke F, Kosan E, Tüfekçi E. White spot lesions in orthodontics: consensus statements for prevention and management. Angle Orthod 2023;93:621–8.
  5. Khoroushi M, Kachuie M. Prevention and treatment of white spot lesions in orthodontic patients. Contemp Clin Dent 2017;8:11.
  6. Temel S, Kaya B. Diagnosis, prevention and treatment of white spot lesions related to orthodontics. Int J Oral Dent Health 2019;5:1–7.
  7. Guzmán-Armstrong S, Chalmers J, Warren JJ. White spot lesions: prevention and treatment. Am J Orthod Dentofacial Orthop 2010;138:690–6.
  8. Wilson RM, Donly KJ. Demineralization around orthodontic brackets bonded with resin-modified glass ionomer cement and fluoride-releasing resin composite. Pediatric Dentistry 2001;23:255–9.
  9. Chatzistavrou E, Eliades T, Zinelis S, Athanasiou AE, Eliades G. Fluoride release from an orthodontic glass ionomer adhesive in vitro and enamel fluoride uptake in vivo. Am J Orthod Dentofacial Orthop 2010;137:458. e1-. e8
  10. Dantagnan C-A, Boudrot M, Francois P, Abdel-Gawad S, Attal J-P. Shear bond strength of a RMGIC for orthodontic bracket bonding to enamel. 2023
  11. Boudrot M, François P, Abdel-Gawad S, Attal J-P, Dantagnan C-A. Shear bond strength of a RMGIC for orthodontic bracket bonding to enamel. BDJ Open 2024;10:1.
  12. Allahverdiyev AM, Kon KV, Abamor ES, Bagirova M, Rafailovich M. Coping with antibiotic resistance: combining nanoparticles with antibiotics and other antimicrobial agents. Expert Rev Anti-infective Therapy 2011;9:1035–52.
  13. Hernández-Sierra JF, Ruiz F, Pena DCC, Martínez-Gutiérrez F, Martínez AE, Guillén AdJP, et al. The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold. Nanomed: Nanotechnol Biol Med 2008;4:237–40.
  14. Zhang K, Melo MAS, Cheng L, Weir MD, Bai Y, Xu HH. Effect of quaternary ammonium and silver nanoparticle-containing adhesives on dentin bond strength and dental plaque microcosm biofilms. Dental Mater 2012;28:842–52.
  15. Beer C, Foldbjerg R, Hayashi Y, Sutherland DS, Autrup H. Toxicity of silver nanoparticles—nanoparticle or silver ion? Toxicol Lett 2012;208:286–92.
  16. Aydin Sevinç B, Hanley L. Antibacterial activity of dental composites containing zinc oxide nanoparticles. J Biomed Mater Res B: Appl Biomater 2010;94:22–31.
  17. Cao B, Wang Y, Li N, Liu B, Zhang Y. Preparation of an orthodontic bracket coated with an nitrogen-doped TiO2-xNy thin film and examination of its antimicrobial performance. Dental Mater J 2013;32:311–6.
  18. Borzabadi-Farahani A, Borzabadi E, Lynch E. Nanoparticles in orthodontics, a review of antimicrobial and anti-caries applications. Acta Odontologica Scandinavica 2014;72:413–7.
  19. ten Cate J. Contemporary perspective on the use of fluoride products in caries prevention. Br Dental J 2013;214:161–7.
  20. Zheng X, Cheng X, Wang L, Qiu W, Wang S, Zhou Y, et al. Combinatorial effects of arginine and fluoride on oral bacteria. J Dental Res 2015;94:344–53.
  21. Shinohara MS, Mario F, Schneider LFJ, Ferracane JL, Pereira PN, Di Hipólito V, Nikaido T. Fluoride-containing adhesive: durability on dentin bonding. Dental Mater 2009;25:1383–91.
  22. Davis HB, Gwinner F, Mitchell JC, Ferracane JL. Ion release from, and fluoride recharge of a composite with a fluoride-containing bioactive glass. Dental Mater 2014;30:1187–94.
  23. Baik A, Alamoudi N, El-Housseiny A, Altuwirqi A. Fluoride varnishes for preventing occlusal dental caries: a review. Dentistry J 2021;9:64.
  24. Nassar Y, Brizuela M. The role of fluoride on caries prevention.■: StatPearls [Internet]: StatPearls Publishing; 2023.
  25. Arifa MK, Ephraim R, Rajamani T. Recent advances in dental hard tissue remineralization: a review of literature. Int J Clin Pediatric Dentistry 2019;12:139.
  26. Mitchell L. An investigation into the effect of a fluoride releasing adhesive on the prevalence of enamel surface changes associated with directly bonded orthodontic attachments. Br J Orthod 1992;19:207–14.
  27. Yi J, Weir MD, Melo MA, Li T, Lynch CD, Oates TW, et al. Novel rechargeable nano-CaF2 orthodontic cement with high levels of long-term fluoride release. J Dentistry 2019;90:103214.
  28. Al Tuma RR, Yassir YA. Evaluation of a newly developed calcium fluoride nanoparticles-containing orthodontic primer: an in-vitro study. J Mech Behav Biomed Mater 2021;122:104691.
  29. Suebsureekul P, Viteporn S. Release of fluoride from orthodontic adhesives and penetration into enamel. J Orofacial Orthop/Fortschritte Kieferorthopadie 2017;78:3.
  30. Årtun J, Bergland S. Clinical trials with crystal growth conditioning as an alternative to acid-etch enamel pretreatment. Am J Orthod 1984;85:333–40.
  31. Abou Neel EA, Aljabo A, Strange A, Ibrahim S, Coathup M, Young AM, et al. Demineralization–remineralization dynamics in teeth and bone. Int J Nanomed 2016:4743–63.
  32. Ghafar H, Khan MI, Sarwar HS, Yaqoob S, Hussain SZ, Tariq I, et al. Development and characterization of bioadhesive film embedded with lignocaine and calcium fluoride nanoparticles. Aaps Pharmscitech 2020;21:1–12.
  33. Sanzari I, Leone A, Ambrosone A. Nanotechnology in plant science: to make a long story short. Front Bioeng Biotechnol 2019;7:120.
  34. Al Tuma RR, Yassir YA. Effect of calcium fluoride nanoparticles in prevention of demineralization during orthodontic fixed appliance treatment: a randomized clinical trial. Eur J Orthod 2023;45:122–32.
  35. Margolis H, Moreno E, Murphy B. Effect of low levels of fluoride in solution on enamel demineralization in vitro. J Dental Res 1986;65:23–9.
  36. Lynch RM, Navada R, Walia R. Low-levels of fluoride in plaque and saliva and their effects on the demineralisation and remineralisation of enamel; role of fluoride toothpastes. Int Dental J 2004;54:304–9.
  37. Pajor K, Pajchel L, Kolmas J. Hydroxyapatite and fluorapatite in conservative dentistry and oral implantology—a review. Materials 2019;12:2683.
  38. Bayrak S, Tunc ES, Aksoy A, Ertas E, Guvenc D, Ozer S. Fluoride release and recharge from different materials used as fissure sealants. Eur J Dentistry 2010;4:245–50.
  39. Patil SS, Kontham UR, Kontham RK, Patil SS, Kamble SP. Fluoride release and fluoride-recharging ability of three different sealants. J Indian Soc Pedodontics Preventive Dent 2020;38:247–52.
  40. Kosior P, Dobrzynski M, Zakrzewska A, Grosman L, Korczynski M, Blicharski T, et al. Preliminary in vitro study of fluoride release from selected ormocer materials. Materials 2021;14:2244.
  41. El Mallakh B, Sarkar N. Fluoride release from glass-ionomer cements in de-ionized water and artificial saliva. Dental Mater 1990;6:118–22.
  42. Rezk-Lega F, Ögaard B, Rölla G. Availability of fluoride from glass-ionomer luting cements in human saliva. Europ J Oral Sci 1991;99:60–3.
  43. Levallois B, Fovet Y, Lapeyre L, Gal JY. In vitro fluoride release from restorative materials in water versus artificial saliva medium (SAGF). Dental Materials 1998;14:441–7.
  44. Kelić M, Kilić D, Kelić K, Šutej I, Par M, Peroš K, Tarle Z. The fluoride ion release from ion-releasing dental materials after surface loading by topical treatment with sodium fluoride gel. J Functional Biomaterials 2023;14:102.
  45. Reynolds I. A review of direct orthodontic bonding. British J Orthod 1975;2:171–8.
  46. Gossett LA. Effects of refrigerant spray on orthodontic composite resin-bracket debond strength and associated adhesive remnant index. University of Missouri-Kansas City; 2012
  47. Mohammed RR, Rafeeq RA. Evaluation of the shear bond strength of chitosan nanoparticles-containing orthodontic primer: an in vitro study. Int J Dentistry 2023;2023.
  48. Pickett KL, Lionel Sadowsky P, Jacobson A, Lacefield W. Orthodontic in vivo bond strength: comparison with in vitro results. Angle Orthod 2001;71:141–8.
  49. Sodagar A, Akhoundi MSA, Bahador A, Jalali YF, Behzadi Z, Elhaminejad F, Mirhashemi AH. Effect of TiO2 nanoparticles incorporation on antibacterial properties and shear bond strength of dental composite used in Orthodontics. Dental Press J Orthod 2017;22:67–74.
  50. Mirhashemi AH, Pourhajibagher M, Zebardast B, Bahrami R, Fard MJK. In vitro effects of antimicrobial properties and shear bond strength of different concentrations of Emodin nanoparticles incorporated orthodontic composites. Int Orthod 2024;22:100836.
  51. Rangrazi A, Daneshmand MS, Ghazvini K, Shafaee H. Effects of magnesium oxide nanoparticles incorporation on shear bond strength and antibacterial activity of an orthodontic composite: an in vitro study. Biomimetics 2022;7:133.
  52. Kumari A, Singla R, Guliani A, Yadav SK. Nanoencapsulation for drug delivery. EXCLI J 2014;13:265.
  53. Makvandi P, Josic U, Delfi M, Pinelli F, Jahed V, Kaya E, et al. Drug delivery (nano) platforms for oral and dental applications: tissue regeneration, infection control, and cancer management. Adv Sci 2021;8:2004014.
  54. Liechty WB, Kryscio DR, Slaughter BV, Peppas NA. Polymers for drug delivery systems. Annu Rev Chem Biomol Eng 2010;1:149–73.
  55. Ahmadi H, Haddadi-Asl V, Ghafari H-A, Ghorbanzadeh R, Mazlum Y, Bahador A. Shear bond strength, adhesive remnant index, and anti-biofilm effects of a photoexcited modified orthodontic adhesive containing curcumin doped poly lactic-co-glycolic acid nanoparticles: An ex-vivo biofilm model of S. mutans on the enamel slab bonded brackets. Photodiagnosis Photodyn Therapy 2020;30:101674.
  56. Behnaz M, Dalaie K, Mirmohammadsadeghi H, Salehi H, Rakhshan V, Aslani F. Shear bond strength and adhesive remnant index of orthodontic brackets bonded to enamel using adhesive systems mixed with tio 2 nanoparticles. Dental Press J Orthod 2018;23:43. e1-. e7
  57. Mirzakouchaki B, Shirazi S, Sharghi R, Shirazi S, Moghimi M, Shahrbaf S. Shear bond strength and debonding characteristics of metal and ceramic brackets bonded with conventional acid-etch and self-etch primer systems: an in-vivo study. J Clin Exp Dent 2016;8:e38.
  58. Mesaroş A, Mesaroş M, Buduru S. Orthodontic bracket removal using LASER-technology—a short systematic literature review of the past 30 years. Materials 2022;15:548.
  59. Yang S-Y, Han AR, Kim K-M, Kwon J-S. Acid neutralizing and remineralizing orthodontic adhesive containing hydrated calcium silicate. J Dent 2022;123:104204.
DOI: https://doi.org/10.2478/aoj-2025-0016 | Journal eISSN: 2207-7480 | Journal ISSN: 2207-7472
Language: English
Page range: 215 - 228
Submitted on: Oct 1, 2024
Accepted on: Apr 1, 2025
Published on: Jun 3, 2025
Published by: Australian Society of Orthodontists Inc.
In partnership with: Paradigm Publishing Services
Publication frequency: 1 times per year

© 2025 Nurin Afrina Syasya Azren, Sunittha Gopala Krishnan, May Nak Lau, Yasmin Kamarudin, Ghee Seong Lim, Nosizana Mohd Salleh, Ninie Suhana Abdul Manan, published by Australian Society of Orthodontists Inc.
This work is licensed under the Creative Commons Attribution 4.0 License.