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Cytotoxicity evaluation of different clear aligner materials using MTT analysis Cover

Cytotoxicity evaluation of different clear aligner materials using MTT analysis

Open Access
|Nov 2022

Figures & Tables

Table I.

Clear aligner brands and their contents.

BrandMaterial contentSupplier
DuranPolyethylene terephalate glycol (PETG)Scheu-Dental GmbH
Essix C+Polypropylene/ethylene copolymer (>95%), stabilizers (<5%)Raintree Essix, Inc.
Smart TrackPolyurethane from methylene diphenyl diisocyanate and 1,6-hexanedial, AdditivesAlign Technology, Inc.
ZenduraPolyurethane resinBay Materials LLC
TaglusPolyethylene terephthalate glycol (PETG)Laxmi Dental Export
Zendura FlxCopolyester and Polyurethane resinBay Materials LLC
Table II.

Cell proliferation obtained from MTT analysis.

Clear alignernMean±SD (Min-Max)Kruskal Wallis Test Statistic** pa** pb*** pc** pd** pe
Duran692.625±26.345
(53.15–124.59)
p=0.001*
Essix C+694.947±8.543
(81.29–103.82)
1.000
Smart Track687.662±5.535
(78.01–93.03)
1.0001.000
Zendura667.31±16.209
(38.13–81.01)
0.3970.4561.000
Taglus6113.183±7.459
(104.51–123.77)
0.9370.8270.0850.001
Zendura Flx6106.922±12.765
(83.75–120.35)
1.0001.0000.5980.0111.000

1* p indicates the differences between groups.

2** Post-hoc binary group comparisons according to Dunn-Bonferroni test: a — Differences between Duran, b — Differences between Essix C+, c — Differences between Smart Track, d — Differences between Zendura, e — Differences between Taglus.

Figure 1.

Percentile score distribution of cell proliferation of primary gingival fibroblasts obtained from MTT analysis in clear aligner groups.

DOI: https://doi.org/10.2478/aoj-2022-0034 | Journal eISSN: 2207-7480 | Journal ISSN: 2207-7472
Language: English
Page range: 348 - 354
Submitted on: Feb 1, 2022
Accepted on: Sep 1, 2022
Published on: Nov 21, 2022
Published by: Australian Society of Orthodontists Inc.
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2022 Esra Cifci Ozkan, Gulay Dumanli Gok, Nazli Ece Ordueri, Tugba Elgun, published by Australian Society of Orthodontists Inc.
This work is licensed under the Creative Commons Attribution 4.0 License.