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Impacts of Using Aloe Vera as a Feed Additive in Aquatic Animals Feeding Trials: A Mini-Review Cover

Impacts of Using Aloe Vera as a Feed Additive in Aquatic Animals Feeding Trials: A Mini-Review

Open Access
|Sep 2026

Figures & Tables

Table 1.

The impacts of Aloe vera and its derivatives as feed additive in aquatic animals

Aloe vera and its derivativesAquatic animal – age/weightDose and durationImpactsReferences
12345
Aloe vera leaf powderJuvenile rockfish, Sebastes schlegeli – 25 g0.5% of diet – 6 weeks↑disease resistance to Vibrio alginolyticus(Kim et al., 1999)
Aloe vera leaf powderMatrinxã, Brycon amazonicus – 84.7 g0.002% – bathing treatment – 2 h↑mitigate stress due to transportation(Zanuzzo et al., 2012)
Aloe vera gelRainbow trout, Oncorhynchus mykiss – 50.3 g0.1–1% of diet – 6 weeks
  • ↑growth performance

  • ↑skin alteration

  • ↑gastrointestinal

  • ↑disease resistance to Streptococcus agalactiae

(Heidarieh, 2013)
Aloe vera and propolis mixture (1:1)Juvenile Nile tilapia, Oreochromis niloticus – 54.3 g0.5–2% of diet – 14 days
  • = hematological profile

  • ↑monocyte and neutrophil phagocytic activity

(Dotta et al., 2014)
Aloe vera leaf powderGIFT tilapia, Oreochromis niloticus – 4.83 g1–2% of diet – 60 days
  • ↑hematological profile

  • ↑growth performance

  • = disease resistance to Streptococcus iniae

(Gabriel et al., 2015)
4% of diet – 60 dayscause anemia
Aloe vera leaf powderSteelhead trout, Oncorhynchus mykiss – 133.9 g0.5% of diet – 6 weeks
  • = growth performance

  • = antioxidative responses

  • = regulate immune-related genes expression

(Zanuzzo et al., 2015)
Aloe vera leaf powder
  • Whiteleg shrimp, Litopenaeus vannamei –

  • Bioassay 1 – 80 mg

  • Bioassay 2 – 104 mg

  • Bioassay 3 – 110 mg

  • 0.1–0.4% of diet –

  • 26 days

  • 11 days

  • 7 days

↑disease resistance to Vibrio parahaemolyticus + white spot syndrome virus (WSSV)(Trejo-Flores et al., 2016)
Aloe vera leaf powderGIFT tilapia, Oreochromis niloticus – 4.83 g1–4% of diet – 42 days↑masculinization effects(Gabriel et al., 2017)
Aloe vera leaf powderPacu, Piaractus mesopotamicus – 71.3 g0.5–2% of diet – 10 days
  • ↑mitigate transportation stress

  • ↑immune system

  • ↑disease resistance to Aeromonas hydrophila

(Zanuzzo et al., 2017)
Aloe vera leaf powderWhiteleg shrimp, Litopenaeus vannamei – 2.9 g0.1% of diet – 72 h↑upregulate immune-related genes expression(Trejo-Flores et al., 2018)
Aloe vera polysaccharidesAfrican catfish, Clarias gariepinus – 3.1 g
  • 0.5–2% of diet – 60 days

  • 0.5–1% of diet – 60 days

  • ↑growth performance

  • ↑resistance to low pH environment

  • ↑hematological profile

(Gabriel et al., 2019)
Aloe-emodinRohu, Labeo rohita – 27.8 g0.0005% of diet – 8 weeks
  • ↑hematological profile

  • ↑immune system

  • ↑disease resistance to Aphanomyces invadans

  • ↑upregulate immune-related genes expression

(Devi et al., 2019)
Aloe vera leaf powderRainbow trout, Oncorhynchus mykiss – 10.89 g1.5% of diet – 8 weeks
  • ↑growth performance

  • ↑immunological parameters

  • ↑upregulated immune-related genes expression

  • ↑disease resistance to Saprolegnia parasitica

(Mehrabi et al., 2019)
Aloe vera leaf powderCommon carp, Cyprinus carpio – 1.73 g0.2–1.6% of diet – 90 days
  • ↑growth performance

  • ↑flesh quality

(Khanal et al., 2021)
Aloe vera and Allium sativum mixture (1:1)African catfish, Clarias gariepinus – 12.28 g1% of diet – 60 days
  • ↑growth performance

  • ↑hematological profile

  • ↑resistance to low pH environment

  • ↑flesh quality – lipid content

(Gabriel et al., 2021)
Aloe vera by-productGolden mullet, Liza aurata – 8.93 g2–6% of diet – 91 days
  • = growth performance

  • = flesh quality

  • ↑immunological parameter at 2% only

  • = antioxidative response

(Quirós-Pozo et al., 2021)
Aloe vera leaf gelAtlantic salmon, Salmo salar – 75 g0.04% – 28 days↑relieve inflammation induced by soybean meal(Fehrmann-Cartes et al., 2022)
Aloe vera leaf powderGilthead sea bream, Sparus aurata – 138.35 g0.5–5% of diet – 60 days
  • = growth performance

  • ↑antioxidative response

  • ↑upregulate growth-related genes expression

  • ↓downregulate lipid metabolism-related genes expression

  • ↑hepatic steatosis

(Amri et al., 2022)
Methanolic Aloe vera leaf extractNile tilapia, Oreochromis niloticus – 4.04 g1–3% of diet – 105 days
  • ↑growth performance

  • ↑hematological profile

(Syed et al., 2022)
Aloe vera gelMori fish, Catla catla – 10 g1–3% of diet – 70 days
  • ↑growth performance

  • ↑flesh quality

  • ↑hematological profile

  • ↑antioxidative response

(Yousaf et al., 2025)

[i] ↑ positive impact; ↓ negative impact; = no impact.

DOI: https://doi.org/10.2478/aoas-2025-0080 | Journal eISSN: 2300-8733 (formerly 1642-3402) | Journal ISSN: 1642-3402
Language: English
Page range: 855 - 864
Submitted on: Apr 6, 2025
Accepted on: Jul 17, 2025
Published on: Sep 26, 2026
Published by: National Research Institute of Animal Production
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Related subjects:

© 2026 Seong Wei Lee, Albaris B. Tahiluddin, Hadiana Hadiana, Ahmad Syazni Kamarudin, Arifullah Mohammed, Nor Azra Mohamad, Lau Kia Kian, Wendy Wee, published by National Research Institute of Animal Production
This work is licensed under the Creative Commons Attribution 4.0 License.