Molecular and Cellular Markers in Chickens Exposed to Stressors and the Ability of Feed Supplements to Overcome Negative Effects –A Review

Alireza Seidavi; Babak Hosseintabar-Ghasemabad; František Zigo; Olga Vilorievna Kvan; Elena Vladimirovna Sheida; Galimzhan Kalihanovich Duskaev; Colin G. Scanes

doi:10.2478/aoas-2024-0110

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Molecular and Cellular Markers in Chickens Exposed to Stressors and the Ability of Feed Supplements to Overcome Negative Effects –A Review

Annals of Animal Science

Volume 25 (2025): Issue 3 (July 2025)

By: Alireza Seidavi, Babak Hosseintabar-Ghasemabad, František Zigo, Olga Vilorievna Kvan, Elena Vladimirovna Sheida, Galimzhan Kalihanovich Duskaev and Colin G. Scanes

Open Access

|Jul 2025

Abstract

Performance of chickens is negatively impacted by stressors such as heat stress, infection with Campylobacter jejuni, the mycotoxins –aflatoxin B₁ and deoxynivalenol, the glucocorticoid dexethasone, insecticides and Eimeria tenella. Effects of stressors include reduced gastrointestinal function and induction of inflammation. Stressors influence the following molecular and cellular structures and functions: gastrointestinal integrity, villus height, crypt depth, mast cell number, expression of pro-inflammatory cytokines, concentrations of leukocytes, and antioxidant status. In multiple studies, adverse effects of multiple stressors were overcome partly by supplementation. The utility of these parameters is discussed and recommendations/guidelines for future research made.

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Articles in this issue

DOI: https://doi.org/10.2478/aoas-2024-0110 | Journal eISSN: 2300-8733 | Journal ISSN: 1642-3402

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Language: English

Page range: 955 - 965

Submitted on: Jun 28, 2024

Accepted on: Sep 27, 2024

Published on: Jul 24, 2025

Published by: National Research Institute of Animal Production

In partnership with: Paradigm Publishing Services

Publication frequency: Volume open

Keywords:

gastrointestinal morphology

Related subjects:

Zoology,

© 2025 Alireza Seidavi, Babak Hosseintabar-Ghasemabad, František Zigo, Olga Vilorievna Kvan, Elena Vladimirovna Sheida, Galimzhan Kalihanovich Duskaev, Colin G. Scanes, published by National Research Institute of Animal Production
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 25 (2025): Issue 3 (July 2025)