Abstract
Respiratory tract infections are the most common infections find at pediatric age. Children with lower respiratory tract infections can presents severe forms, which is why early diagnosis and treatment are essential. Choosing the therapy is made according to the etiology, but at the time of admission it is difficult to establish the etiology of the disease and for this reason, most often, it is decided to initiate the antibiotic therapy. Excessive antibiotic prescription, in cases that it is not justified, is really a problem because it contributes to the increase of antimicrobial resistance. A study was conducted in order to limit the hypothesis of prolonged antibiotic therapy, which also prolongs the duration of hospitalization. By anticipating C-reactive protein and procalcitonin levels we could guide or reconsider the antibiotic treatment.