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Establishment of Acenocoumarol Pharmacogenetic Algorithm Including CYP2C9 and VKORC1 Genotypes in Bulgarian Patients Treated with Coumarin Anticoagulants Cover

Establishment of Acenocoumarol Pharmacogenetic Algorithm Including CYP2C9 and VKORC1 Genotypes in Bulgarian Patients Treated with Coumarin Anticoagulants

Open Access
|Jun 2025

Authors

R. Tzveova

renitzveova@abv.bg

Institute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences – Sofia, Bulgaria

R. Saraeva

Eurofins Biomnis – Lyon, France

A. Dimitrova-Karamfilova

Department of Clinical Laboratory, XXV Diagnostic Consultative Center – Sofia, Bulgaria

G. Nachev

Department of Cardiovascular Surgery, University Multiprofile Hospital for Active Treatment “Sv. Ekaterina” – Sofia, Bulgaria

V. Mitev

Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University – Sofia, Bulgaria

R. Kaneva

Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University – Sofia, Bulgaria

D. Pendicheva-Duhlenska

Department of Pharmacology, Faculty of Pharmacy, Medical University – Pleven, Bulgaria
DOI: https://doi.org/10.2478/amb-2025-0039 | Journal eISSN: 2719-5384 | Journal ISSN: 0324-1750
Language: English
Page range: 12 - 23
Submitted on: Aug 22, 2024
|
Accepted on: Feb 3, 2025
|
Published on: Jun 19, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 R. Tzveova, R. Saraeva, A. Dimitrova-Karamfilova, G. Nachev, V. Mitev, R. Kaneva, D. Pendicheva-Duhlenska, published by Medical University - Sofia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.