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Understanding Probiotics, Prebiotics, Synbiotics, and Postbiotics: A Comprehensive Review of the Newest Definitions, Selected Strains and Products Cover

Understanding Probiotics, Prebiotics, Synbiotics, and Postbiotics: A Comprehensive Review of the Newest Definitions, Selected Strains and Products

Advancements of Microbiology
Volume 64 (2025): Issue 3 (September 2025)
By:
Open Access
|Sep 2025

References

  1. <bold>Abouelela ME, Helmy YA</bold>. Next-generation probiotics as novel therapeutics for improving human health: current trends and future perspectives. Microorganisms. 2024 Mar; 12:430. <a href="https://doi.org/10.3390/microorganisms12030430" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/microorganisms12030430</a>
    Search in Google ScholarBack to article
  2. <bold>Aggarwal S, Sabharwal V, Kaushik P, et al</bold>. Postbiotics: from emerging concept to application. Front Sustain Food Syst. 2022 May; 6:887642. <a href="https://doi.org/10.3389/fsufs.2022.887642" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fsufs.2022.887642</a>
    Search in Google ScholarBack to article
  3. <bold>Aleman RS, Moncada M, Aryana KJ</bold>. Leaky Gut and the Ingredients That Help Treat It: A Review. Molecules. 2023 Jan; 28:619. <a href="https://doi.org/10.3390/MOLECULES28020619" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/MOLECULES28020619</a>
    Search in Google ScholarBack to article
  4. <bold>Al-Fakhrany OM, Elekhnawy E</bold>. Next-generation probiotics: the upcoming biotherapeutics. Mol Biol Rep. 2024 Jan; 51:505–515. <a href="https://doi.org/10.1007/s11033-024-09398-5" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s11033-024-09398-5</a>
    Search in Google ScholarBack to article
  5. <bold>Andresen V, Gschossmann J, Layer P</bold>. Heat-inactivated Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial. Lancet Gastroenterol Hepatol. 2020 Aug; 5:658–666. <a href="https://doi.org/10.1016/S2468-1253(20)30056-X" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/S2468-1253(20)30056-X</a>
    Search in Google ScholarBack to article
  6. <bold>Arumugam M, Raes J, Pelletier E, et al</bold>. Enterotypes of the human gut microbiome. Nature. 2011 May; 473:174–180. <a href="https://doi.org/10.1038/NATURE09944" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/NATURE09944</a>
    Search in Google ScholarBack to article
  7. <bold>Barros CP, Grom LC, Guimarães JT, et al</bold>. Paraprobiotic obtained by ohmic heating added in whey–grape juice drink is effective to control postprandial glycemia in healthy adults. Food Res Int. 2021 Apr; 140:109905. <a href="https://doi.org/10.1016/j.foodres.2020.109905" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.foodres.2020.109905</a>
    Search in Google ScholarBack to article
  8. <bold>Beane KE, Redding MC, Wang X, et al</bold>. Effects of dietary fibers, micronutrients, and phytonutrients on gut microbiome: a review. Appl Biol Chem. 2021 May; 64:36. <a href="https://doi.org/10.1186/s13765-021-00605-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/s13765-021-00605-6</a>
    Search in Google ScholarBack to article
  9. <bold>Bolzon V, Bulfoni M, Pesando M, et al</bold>. A streamlined workflow for a fast and cost-effective count of tyndallized probiotics using flow cytometry. Front Microbiol. 2024 Aug; 15:1389069. <a href="https://doi.org/10.3389/fmicb.2024.1389069" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fmicb.2024.1389069</a>
    Search in Google ScholarBack to article
  10. <bold>Boyte ME, Benkowski A, Pane M, Shehata HR</bold>. Probiotic and postbiotic analytical methods: a perspective of available enumeration techniques. Front Microbiol. 2023 Nov; 14:1304621. <a href="https://doi.org/10.3389/fmicb.2023.1304621" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fmicb.2023.1304621</a>
    Search in Google ScholarBack to article
  11. <bold>Buccigrossi V, Poeta M, Cioffi V, et al</bold>. Lacticaseibacillus rhamnosus GG counteracts rotavirus-induced ion secretion and enterocyte damage by inhibiting oxidative stress and apoptosis through specific effects of living and postbiotic preparations. Front Cell Infect Microbiol. 2022 Feb; 12:854989. <a href="https://doi.org/10.3389/fcimb.2022.854989" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fcimb.2022.854989</a>
    Search in Google ScholarBack to article
  12. <bold>Bulygin I, Shatov V, Rykachevskiy A, et al</bold>. Absence of enterotypes in the human gut microbiomes reanalyzed with non-linear dimensionality reduction methods. PeerJ. 2023 Jun; 9:e15838. <a href="https://doi.org/10.7717/PEERJ.15838/SUPP-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.7717/PEERJ.15838/SUPP-1</a>
    Search in Google ScholarBack to article
  13. <bold>Bustos Fernández LM, Man F, Lasa JS</bold>. Impact of Saccharomyces boulardii CNCM I-745 on Bacterial Overgrowth and Composition of Intestinal Microbiota in Diarrhea-Predominant Irritable Bowel Syndrome Patients: Results of a Randomized Pilot Study. Dig Dis. 2023 May; 41:798–809. <a href="https://doi.org/10.1159/000528954" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1159/000528954</a>
    Search in Google ScholarBack to article
  14. <bold>Caballero-Flores G, Pickard JM, Núñez G</bold>. Microbiota-mediated colonization resistance: mechanisms and regulation. Nat Rev Microbiol. 2023 May; 21:347–360. <a href="https://doi.org/10.1038/S41579-022-00833-7" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41579-022-00833-7</a>
    Search in Google ScholarBack to article
  15. <bold>Carucci L, Nocerino R, Paparo L, et al</bold>. Therapeutic effects elicited by the probiotic Lacticaseibacillus rhamnosus GG in children with atopic dermatitis. The results of the ProPAD trial. Pediatr Allergy Immunol. 2022 Aug; 33:e13836. <a href="https://doi.org/10.1111/pai.13836" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/pai.13836</a>
    Search in Google ScholarBack to article
  16. <bold>Cerdó T, Ruíz A, Acuña I, et al</bold>. A synbiotics, long chain polyunsaturated fatty acids, and milk fat globule membranes supplemented formula modulates microbiota maturation and neurodevelopment. Clin Nutr. 2022 Oct; 41:1697–1711. <a href="https://doi.org/10.1016/j.clnu.2022.05.013" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.clnu.2022.05.013</a>
    Search in Google ScholarBack to article
  17. <bold>Chae YR, Lee YR, Kim YS, Park HY</bold>. Diet-Induced Gut Dysbiosis and Leaky Gut Syndrome. J Microbiol Biotechnol. 2024 May; 34:747. <a href="https://doi.org/10.4014/JMB.2312.12031" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.4014/JMB.2312.12031</a>
    Search in Google ScholarBack to article
  18. <bold>Chen PR, Wei Y, Li X, et al</bold>. Precision engineering of the probiotic Escherichia coli Nissle 1917 with prime editing. Appl Environ Microbiol. 2025 Mar; 91:e00031-25. <a href="https://doi.org/10.1128/AEM.00031-25" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1128/AEM.00031-25</a>
    Search in Google ScholarBack to article
  19. <bold>Chen T, Long W, Zhang C, et al</bold>. Fiber-utilizing capacity varies in Prevotella-versus Bacteroides-dominated gut microbiota. Sci Rep. 2017 Jun; 7:2594. <a href="https://doi.org/10.1038/S41598-017-02995-4" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41598-017-02995-4</a>
    Search in Google ScholarBack to article
  20. <bold>Cheng L-H, Liu Y-W, Wu C-C, et al</bold>. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. J Food Drug Anal. 2019 Apr; 27:632–648. <a href="https://doi.org/10.1016/j.jfda.2019.01.002" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.jfda.2019.01.002</a>
    Search in Google ScholarBack to article
  21. <bold>Cheng M, Ning K</bold>. Stereotypes About Enterotype: The Old and New Ideas. Genomics Proteomics Bioinformatics. 2019 Feb; 17:4–12. <a href="https://doi.org/10.1016/J.GPB.2018.02.004" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.GPB.2018.02.004</a>
    Search in Google ScholarBack to article
  22. <bold>Chollet L, Heumel S, Deruyter L, et al</bold>. Faecalibacterium duncaniae as a novel next generation probiotic against influenza. Front Immunol. 2024 Jul; 15:1347676. <a href="https://doi.org/10.3389/FIM-MU.2024.1347676/FULL" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/FIM-MU.2024.1347676/FULL</a>
    Search in Google ScholarBack to article
  23. <bold>Christensen L, Sørensen CV, Wøhlk FU, et al</bold>. Microbial enterotypes beyond genus level: Bacteroides species as a predictive biomarker for weight change upon controlled intervention with arabinoxylan oligosaccharides in overweight subjects. Gut Microbes. 2020 Dec; 12:1847627. <a href="https://doi.org/10.1080/19490976.2020.1847627" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2020.1847627</a>
    Search in Google ScholarBack to article
  24. <bold>Cordaillat-Simmons M, Rouanet A, Pot B</bold>. Live biotherapeutic products: the importance of a defined regulatory framework. Exp Mol Med. 2020 Aug; 52:1397–1406. <a href="https://doi.org/10.1038/S12276-020-0437-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S12276-020-0437-6</a>
    Search in Google ScholarBack to article
  25. <bold>Costea PI, Hildebrand F, Manimozhiyan A, et al</bold>. Enterotypes in the landscape of gut microbial community composition. Nat Microbiol. 2017 Jan; 3:8–16. <a href="https://doi.org/10.1038/S41564-017-0072-8" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41564-017-0072-8</a>
    Search in Google ScholarBack to article
  26. <bold>Cukrowska B, Ceregra A, Maciorkowska E, et al</bold>. The Effectiveness of Probiotic Lactobacillus rhamnosus and Lactobacillus casei Strains in Children with Atopic Dermatitis and Cow’s Milk Protein Allergy: A Multicenter, Randomized, Double Blind, Placebo Controlled Study. Nutrients. 2021 Apr; 13:1169. <a href="https://doi.org/10.3390/NU13041169" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU13041169</a>
    Search in Google ScholarBack to article
  27. <bold>Culp EJ, Goodman AL. Cross-feeding in the gut microbiome: ecology and mechanisms</bold>. Cell Host Microbe. 2023 Apr; 31:485–499. <a href="https://doi.org/10.1016/J.CHOM.2023.03.016" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.CHOM.2023.03.016</a>
    Search in Google ScholarBack to article
  28. <bold>da Silva Vale A, de Melo Pereira GV, de Oliveira AC, et al</bold>. Production, Formulation, and Application of Postbiotics in the Treatment of Skin Conditions. Fermentation. 2023 Mar; 9:264. <a href="https://doi.org/10.3390/FERMENTATION9030264/S1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/FERMENTATION9030264/S1</a>
    Search in Google ScholarBack to article
  29. <bold>Daniali M, Nikfar S, Abdollahi M</bold>. Antibiotic resistance propagation through probiotics. Expert Opin Drug Metab Toxicol. 2020 Dec; 16:1207–1215. <a href="https://doi.org/10.1080/17425255.2020.1825682" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/17425255.2020.1825682</a>
    Search in Google ScholarBack to article
  30. <bold>De Bruyn F, James K, Cottenet G, et al</bold>. Combining Bifidobacterium longum subsp. infantis and human milk oligosaccharides synergistically increases short chain fatty acid production ex vivo. Commun Biol. 2024 Feb; 7:146. <a href="https://doi.org/10.1038/S42003-024-06628-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S42003-024-06628-1</a>
    Search in Google ScholarBack to article
  31. <bold>Di Chiano M, Sallustio F, Fiocco D, et al</bold>. Psychobiotic properties of Lactiplantibacillus plantarum in neurodegenerative diseases. Int J Mol Sci. 2024 Sep; 25:9489. <a href="https://doi.org/10.3390/IJMS25179489" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/IJMS25179489</a>
    Search in Google ScholarBack to article
  32. <bold>Di Tommaso N, Gasbarrini A, Ponziani FR</bold>. Intestinal Barrier in Human Health and Disease. Int J Environ Res Public Health. 2021 Dec; 18:12836. <a href="https://doi.org/10.3390/IJERPH182312836" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/IJERPH182312836</a>
    Search in Google ScholarBack to article
  33. <bold>Ding Q, Sun X, Cao S, et al</bold>. Heat-killed <em>Lactobacillus acidophilus</em> mediates <em>Fusobacterium nucleatum</em>-induced pro-inflammatory responses in epithelial cells. FEMS Microbiol Lett. 2021 Jan; 368:fnab160. <a href="https://doi.org/10.1093/femsle/fnab160" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1093/femsle/fnab160</a>
    Search in Google ScholarBack to article
  34. <bold>Docampo MJ, Batruch M, Oldrati P, et al</bold>. Clinical and immunologic effects of paraprobiotics in long-COVID patients: a pilot study. Neurol Neuroimmunol Neuroinflamm. 2024 Mar; 11:e200296. <a href="https://doi.org/10.1212/nxi.0000000000200296" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1212/nxi.0000000000200296</a>
    Search in Google ScholarBack to article
  35. <bold>Dziedzic A, Maciak K, Bliźniewska-Kowalska K, et al</bold>. The power of psychobiotics in depression: a modern approach through the microbiota–gut–brain axis: a literature review. Nutrients. 2024 Apr; 16:1054. <a href="https://doi.org/10.3390/NU16071054" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU16071054</a>
    Search in Google ScholarBack to article
  36. <bold>Eguren C, Navarro-Blasco A, Corral-Forteza M, et al</bold>. A Randomized Clinical Trial to Evaluate the Efficacy of an Oral Probiotic in Acne Vulgaris. Acta Derm Venereol. 2024 Mar; 104:33206. <a href="https://doi.org/10.2340/ACTADV.V104.33206" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.2340/ACTADV.V104.33206</a>
    Search in Google ScholarBack to article
  37. <bold>El-Sayed A, Aleya L, Kamel M</bold>. Microbiota’s role in health and diseases. Environ Sci Pollut Res Int. 2021 Jul; 28:36967. <a href="https://doi.org/10.1007/S11356-021-14593-Z" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/S11356-021-14593-Z</a>
    Search in Google ScholarBack to article
  38. <bold>Esawie M, Matboli M, Bushra MS, et al</bold>. ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats. Diabetol Metab Syndr. 2025 Jan; 17:45. <a href="https://doi.org/10.1186/S13098-025-01600-3" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S13098-025-01600-3</a>
    Search in Google ScholarBack to article
  39. European Pharmacopoeia Commission. Live biotherapeutic products for human use (3053). European Pharmacopoeia. 2018.
    Search in Google ScholarBack to article
  40. <bold>Eze UJ, Lal A, Elkoush MI, et al</bold>. Recurrent Lactobacillus rhamnosus bacteremia and complications in an immunocompromised patient with history of probiotic use: a case report. Cureus. 2024 Apr; 16(4):e54879. <a href="https://doi.org/10.7759/cureus.54879" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.7759/cureus.54879</a>
    Search in Google ScholarBack to article
  41. FAO/WHO. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. FAO/WHO Report. 2001. Accessed 2 Dec 2024
    Search in Google ScholarBack to article
  42. FDA. Early clinical trials with live biotherapeutic products: chemistry, manufacturing, and control information; guidance for industry. FDA Guidance. 2016.
    Search in Google ScholarBack to article
  43. <bold>Flaujac Lafontaine GM, Fish NM, Connerton IF</bold>. In vitro evaluation of the effects of commercial prebiotic GOS and FOS products on human colonic Caco–2 cells. Nutrients. 2020 May; 12:1281. <a href="https://doi.org/10.3390/NU12051281" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU12051281</a>
    Search in Google ScholarBack to article
  44. <bold>Franciosa G, Guida S, Jesus Gomez Miguel M, Von Hunolstein C</bold>. Live biotherapeutic products and their regulatory framework in Italy and Europe. Ann Ist Super Sanità. 2023 Jan; 59:56–67. <a href="https://doi.org/10.4415/ann_23_01_09" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.4415/ann_23_01_09</a>
    Search in Google ScholarBack to article
  45. <bold>Gao G, Ma T, Zhang T, et al</bold>. Adjunctive Probiotic Lactobacillus rhamnosus Probio-M9 Administration Enhances the Effect of An-ti-PD-1 Antitumor Therapy via Restoring Antibiotic-Disrupted Gut Microbiota. Front Immunol. 2021 Dec; 14:12:772532. <a href="https://doi.org/10.3389/FIMMU.2021.772532" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/FIMMU.2021.772532</a>
    Search in Google ScholarBack to article
  46. <bold>Garcia-Vello P, Tytgat HLP, Elzinga J, et al</bold>. The lipooligosaccharide of the gut symbiont Akkermansia muciniphila exhibits a remarkable structure and TLR signaling capacity. Nat Commun. 2024 Jan; 15(1):12. <a href="https://doi.org/10.1038/s41467-024-52683-x" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/s41467-024-52683-x</a>
    Search in Google ScholarBack to article
  47. <bold>Garvey SM, Mah E, Blonquist TM, et al</bold>. The probiotic Bacillus subtilis BS50 decreases gastrointestinal symptoms in healthy adults: a randomized, double-blind, placebo-controlled trial. Gut Microbes. 2022 Nov; 14:2122668. <a href="https://doi.org/10.1080/19490976.2022.2122668" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2022.2122668</a>
    Search in Google ScholarBack to article
  48. <bold>Ghyselinck J, Teixeira J, Marzorati M, Harthoorn L</bold>. A novel synbiotic blend of galactooligosaccharide (GOS) and a two-strain probiotic acts synergistically to increase lactate and short-chain fatty acid production in a short-term ex vivo colon fermentation model‥ Int J Nutr Sci. 2024 Mar; 9(1): 1082
    Search in Google ScholarBack to article
  49. <bold>Gibson GR, Hutkins R, Sanders ME, et al</bold>. The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol. 2017 Aug; 14:491–502. <a href="https://doi.org/10.1038/nrgastro.2017.75" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/nrgastro.2017.75</a>
    Search in Google ScholarBack to article
  50. <bold>Gibson GR, Roberfroid MB</bold>. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995 Jun; 125:1401–1412. <a href="https://doi.org/10.1093/JN/125.6.1401" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1093/JN/125.6.1401</a>
    Search in Google ScholarBack to article
  51. <bold>Gomez Quintero DF, Kok CR, Hutkins R</bold>. The future of synbiotics: rational formulation and design. Front Microbiol. 2022 Jul; 13:919725. <a href="https://doi.org/10.3389/FMICB.2022.919725" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/FMICB.2022.919725</a>
    Search in Google ScholarBack to article
  52. <bold>Gorvitovskaia A, Holmes SP, Huse SM</bold>. Interpreting Prevotella and Bacteroides as biomarkers of diet and lifestyle. Microbiome. 2016 Aug; 4:276. <a href="https://doi.org/10.1186/S40168-016-0160-7" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S40168-016-0160-7</a>
    Search in Google ScholarBack to article
  53. <bold>Gurbatri CR, Radford GA, Vrbanac L, et al</bold>. Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia. Nat Commun. 2024 Jan; 15:646. <a href="https://doi.org/10.1038/S41467-024-44776-4" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41467-024-44776-4</a>
    Search in Google ScholarBack to article
  54. <bold>Hasnain MA, Kang D, Moon GS</bold>. Research trends of next generation probiotics. Food Sci Biotechnol. 2024 Aug; 33:2111–2121. <a href="https://doi.org/10.1007/S10068-024-01626-9" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/S10068-024-01626-9</a>
    Search in Google ScholarBack to article
  55. <bold>Hays KE, Pfaffinger JM, Ryznar R</bold>. The interplay between gut microbiota, short-chain fatty acids, and implications for host health and disease. Gut Microbes. 2024 Jul; 16:2393270. <a href="https://doi.org/10.1080/19490976.2024.2393270" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2024.2393270</a>
    Search in Google ScholarBack to article
  56. <bold>He C, Xie Y, Zhu Y, et al</bold>. Probiotics modulate gastrointestinal microbiota after Helicobacter pylori eradication: A multicenter randomized double-blind placebo-controlled trial. Front Immunol. 2022 Oct; 13:1033063. <a href="https://doi.org/10.3389/fimmu.2022.1033063" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fimmu.2022.1033063</a>
    Search in Google ScholarBack to article
  57. <bold>Hill C, Guarner F, Reid G, et al</bold>. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014 Jul; 11:506–514. <a href="https://doi.org/10.1038/nrgastro.2014.66" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/nrgastro.2014.66</a>
    Search in Google ScholarBack to article
  58. <bold>Hillestad EMR, van der Meeren A, Nagaraja BH, et al</bold>. Gut bless you: The microbiota-gut-brain axis in irritable bowel syndrome. World J Gastroenterol. 2022 Jan; 28:412–431. <a href="https://doi.org/10.3748/WJG.V28.I4.412" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3748/WJG.V28.I4.412</a>
    Search in Google ScholarBack to article
  59. <bold>Hutkins R, Walter J, Gibson GR, et al</bold>. Classifying compounds as prebiotics—scientific perspectives and recommendations. Nat Rev Gastroenterol Hepatol. 2024 Jan; 22:54–70. <a href="https://doi.org/10.1038/s41575-024-00981-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/s41575-024-00981-6</a>
    Search in Google ScholarBack to article
  60. <bold>Ioannou A, Berkhout MD, Geerlings SY, Belzer C</bold>. Akkermansia muciniphila: biology, microbial ecology, host interactions and therapeutic potential. Nat Rev Microbiol. 2024 Mar; 23(3):162-177. <a href="https://doi.org/10.1038/s41579-024-01106-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/s41579-024-01106-1</a>
    Search in Google ScholarBack to article
  61. <bold>Ivashkin V, Maev I, Poluektova E, et al</bold>. Efficacy and Safety of Postbiotic Contained Inactivated Lactobacillus reuteri (Limosi-lactobacillus reuteri) DSM17648 as Adjuvant Therapy in the Eradication of Helicobacter pylori in Adults With Functional Dyspepsia: A Randomized Double-Blind Placebo-Controlled Trial. Clin Transl Gastroenterol. 2024 Jan; 15:e1. <a href="https://doi.org/10.14309/CTG.0000000000000750" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.14309/CTG.0000000000000750</a>
    Search in Google ScholarBack to article
  62. <bold>Jamieson PE, Smart EB, Bouranis JA, et al</bold>. Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults. Gut Microbes. 2024 Jan; 16:2315633. <a href="https://doi.org/10.1080/19490976.2024.2315633" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2024.2315633</a>
    Search in Google ScholarBack to article
  63. <bold>Jenkins G, Mason P</bold>. The role of prebiotics and probiotics in human health: a systematic review with a focus on gut and immune health. Food Nutr J. 2022 Aug; 7:245. <a href="https://doi.org/10.29011/2575-7091.100245" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.29011/2575-7091.100245</a>
    Search in Google ScholarBack to article
  64. <bold>Jiao J, Xu P, Wang X, et al</bold>. Enterotypes in asthenospermia patients with obesity. Sci Rep. 2022 Oct; 12:17134. <a href="https://doi.org/10.1038/S41598-022-20574-0" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41598-022-20574-0</a>
    Search in Google ScholarBack to article
  65. <bold>Jung S, Kim KM, Youn SM, Kim KN</bold>. A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effects of Multi-Strain Synbiotic in Patients with Functional Diarrhea and High Fecal Calprotectin Levels: A Pilot Study. Nutrients. 2022 Dec; 14:5017. <a href="https://doi.org/10.3390/nu14235017" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/nu14235017</a>
    Search in Google ScholarBack to article
  66. <bold>Kang CH, Jung ES, Jung SJ, et al</bold>. Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2024 Dec; 16:4037. <a href="https://doi.org/10.3390/NU16234037" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU16234037</a>
    Search in Google ScholarBack to article
  67. <bold>Katkowska M, Garbacz K, Kusiak A</bold>. Probiotics: Should All Patients Take Them? Microorganisms. 2021 Dec; 9:2620. <a href="https://doi.org/10.3390/MICROORGANISMS9122620" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/MICROORGANISMS9122620</a>
    Search in Google ScholarBack to article
  68. <bold>Kato K, Arai S, Sato S, et al</bold>. Effects of heat-killed Lacticaseibacillus paracasei MCC1849 on immune parameters in healthy adults—a randomized, double-blind, placebo-controlled, parallel-group study. Nutrients. 2024 Jan; 16:216. <a href="https://doi.org/10.3390/NU16020216" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU16020216</a>
    Search in Google ScholarBack to article
  69. <bold>Kim CS, Cha L, Sim M, et al</bold>. Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial. J Gerontol A Biol Sci Med Sci. 2020 Nov; 76:32–40. <a href="https://doi.org/10.1093/GERONA/GLAA090" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1093/GERONA/GLAA090</a>
    Search in Google ScholarBack to article
  70. <bold>Kleerebezem M, Führen J</bold>. Synergistic vs. complementary synbiotics: the complexity of discriminating synbiotic concepts using a Lactiplantibacillus plantarum exemplary study. Microbiome Res Rep. 2024 Aug; 3:46. <a href="https://doi.org/10.20517/MRR.2024.48" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.20517/MRR.2024.48</a>
    Search in Google ScholarBack to article
  71. <bold>Kwoji ID, Aiyegoro OA, Okpeku M, Adeleke MA</bold>. Multi-Strain Probiotics: Synergy among Isolates Enhances Biological Activities. Biology (Basel). 2021 Apr; 10:322. <a href="https://doi.org/10.3390/BIOLOGY10040322" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/BIOLOGY10040322</a>
    Search in Google ScholarBack to article
  72. <bold>Lai H, Li Y, He Y, et al</bold>. Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial. Gut Microbes. 2023 May; 15:2197837. <a href="https://doi.org/10.1080/19490976.2023.2197837" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2023.2197837</a>
    Search in Google ScholarBack to article
  73. <bold>Lau RI, Su Q, Lau ISF, et al</bold>. A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2024 Feb; 24:256–265. <a href="https://doi.org/10.1016/S1473-3099(23)00685-0" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/S1473-3099(23)00685-0</a>
    Search in Google ScholarBack to article
  74. <bold>Lee M, Bang WY, Lee HB, et al</bold>. Safety assessment and evaluation of probiotic potential of Lactobacillus bulgaricus IDCC 3601 for human use. Microorganisms. 2024 Oct; 12:2063. <a href="https://doi.org/10.3390/MICROORGANISMS12102063/S1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/MICROORGANISMS12102063/S1</a>
    Search in Google ScholarBack to article
  75. <bold>Lee NK, Park YS, Kang DK, Paik HD</bold>. Paraprobiotics: definition, manufacturing methods, and functionality. Food Sci Biotechnol. 2023 Nov; 32:1981–1993. <a href="https://doi.org/10.1007/s10068-023-01378-y" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s10068-023-01378-y</a>
    Search in Google ScholarBack to article
  76. <bold>Lee S, You H, Lee M, et al</bold>. Different reactions in each enterotype depending on the intake of probiotic yogurt powder. Microorganisms. 2021 Jun; 9:1277. <a href="https://doi.org/10.3390/MICROORGANISMS9061277/S1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/MICROORGANISMS9061277/S1</a>
    Search in Google ScholarBack to article
  77. <bold>Leser T, Baker A</bold>. Molecular mechanisms of Lacticaseibacillus rhamnosus, LGG® probiotic function. Microorganisms. 2024 Apr; 12(4):794. <a href="https://doi.org/10.3390/microorganisms12040794" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/microorganisms12040794</a>
    Search in Google ScholarBack to article
  78. <bold>Li X, Hu S, Yin J, et al</bold>. Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial. Gut Microbes. 2023 Aug; 15:2247025. <a href="https://doi.org/10.1080/19490976.2023.2247025" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2023.2247025</a>
    Search in Google ScholarBack to article
  79. <bold>Liang C, Tseng HC, Chen HM, et al</bold>. Diversity and enterotype in gut bacterial community of adults in Taiwan. BMC Genomics. 2017 Dec; 18:932. <a href="https://doi.org/10.1186/S12864-016-3261-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S12864-016-3261-6</a>
    Search in Google ScholarBack to article
  80. <bold>Liang D, Wu F, Zhou D, et al</bold>. Commercial probiotic products in public health: current status and potential limitations. Crit Rev Food Sci Nutr. 2024 Jul; 64:6455–6476. <a href="https://doi.org/10.1080/10408398.2023.2169858" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/10408398.2023.2169858</a>
    Search in Google ScholarBack to article
  81. <bold>Lilly DM, Stillwell RH</bold>. Probiotics: growth-promoting factors produced by microorganisms. Science. 1965 Feb; 147:747–748. <a href="https://doi.org/10.1126/SCIENCE.147.3659.747" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1126/SCIENCE.147.3659.747</a>
    Search in Google ScholarBack to article
  82. <bold>Liu YW, Liong MT, Chung YCE, et al</bold>. Effects of Lactobacillus plantarum PS128 on children with autism spectrum disorder in Taiwan: a randomized, double-blind, placebo-controlled trial. Nutrients. 2019 Apr; 11:820. <a href="https://doi.org/10.3390/nu11040820" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/nu11040820</a>
    Search in Google ScholarBack to article
  83. <bold>Logan AC, Katzman M</bold>. Major depressive disorder: probiotics may be an adjuvant therapy. Med Hypotheses. 2005 Mar; 64:533–538. <a href="https://doi.org/10.1016/j.mehy.2004.08.019" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.mehy.2004.08.019</a>
    Search in Google ScholarBack to article
  84. <bold>Łukasik J, Dierikx T, Besseling-Van Der Vaart I, et al</bold>. Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. JAMA Pediatr. 2022 Aug; 176:860. <a href="https://doi.org/10.1001/JAMAPEDIATRICS.2022.1973" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1001/JAMAPEDIATRICS.2022.1973</a>
    Search in Google ScholarBack to article
  85. <bold>Ma J, Lyu Y, Liu X, et al</bold>. Engineered probiotics. Microb Cell Fact. 2022 Feb; 21:9. <a href="https://doi.org/10.1186/S12934-022-01799-0" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S12934-022-01799-0</a>
    Search in Google ScholarBack to article
  86. <bold>Ma L, Tu H, Chen T</bold>. Postbiotics in Human Health: A Narrative Review. Nutrients. 2023 Jan; 15:291. <a href="https://doi.org/10.3390/NU15020291" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU15020291</a>
    Search in Google ScholarBack to article
  87. <bold>Magalhães-Guedes KT</bold>. Psychobiotic therapy: method to reinforce the immune system. Clin Psychopharmacol Neurosci. 2022 Jan; 20:17. <a href="https://doi.org/10.9758/CPN.2022.20.1.17" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.9758/CPN.2022.20.1.17</a>
    Search in Google ScholarBack to article
  88. <bold>Maldonado Galdeano C, Cazorla SI, María J, et al</bold>. Beneficial Effects of Probiotic Consumption on the Immune System. Review Article. Ann Nutr Metab. 2019 Jan; 74:115–124. <a href="https://doi.org/10.1159/000496426" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1159/000496426</a>
    Search in Google ScholarBack to article
  89. <bold>Mändar R, Sõerunurk G, Štšepetova J, et al</bold>. Impact of Lactobacillus crispatus-containing oral and vaginal probiotics on vaginal health: a randomised double-blind placebo controlled clinical trial. Benef Microbes. 2023 Apr; 14:143–152. <a href="https://doi.org/10.3920/BM2022.0091" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3920/BM2022.0091</a>
    Search in Google ScholarBack to article
  90. <bold>Markowiak P, Śliżewska K</bold>. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017 Sep; 9:1021. <a href="https://doi.org/10.3390/NU9091021" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU9091021</a>
    Search in Google ScholarBack to article
  91. <bold>Markowska E, Kiersztan A</bold>. Akkermansia muciniphila – a promising candidate for a next generation probiotic. Postepy Hig Med Dosw. 2021; 75:724–748. <a href="https://doi.org/10.2478/AHEM-2021-0036" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.2478/AHEM-2021-0036</a>
    Search in Google ScholarBack to article
  92. <bold>Martinović A, Chittaro M, Mora D, Arioli S</bold>. The ability of Streptococcus thermophilus BT01 to modulate urease activity in healthy subjects’ fecal samples depends on the biomass production process. Mol Nutr Food Res. 2023 Mar; 67:e2200529. <a href="https://doi.org/10.1002/mnfr.202200529" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/mnfr.202200529</a>
    Search in Google ScholarBack to article
  93. <bold>Mayer EA, Nance K, Chen S</bold>. The Gut-Brain Axis. Annu Rev Med. 2022 Jan; 73:439–453. <a href="https://doi.org/10.1146/annurev-med-042320" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1146/annurev-med-042320</a>
    Search in Google ScholarBack to article
  94. <bold>McFarland LV</bold>. Efficacy of single-strain probiotics versus multistrain mixtures: systematic review of strain and disease specificity. Dig Dis Sci. 2021 Mar;66(3):694–704. <a href="https://doi.org/10.1007/S10620-020-06244-Z" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/S10620-020-06244-Z</a>
    Search in Google ScholarBack to article
  95. <bold>Mellai M, Allesina M, Edoardo B, et al</bold>. A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of Opuntia ficus-indica Prebiotic Supplementation in Subjects with Gut Dysbiosis. Nutrients. 2024 Feb; 16:586. <a href="https://doi.org/10.3390/nu16050586" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/nu16050586</a>
    Search in Google ScholarBack to article
  96. <bold>Metchnikoff E</bold>. Lactic acid as inhibiting intestinal putrefaction. In: The prolongation of life: Optimistic studies. London: William Heinemann; 1907. p. 161–183
    Search in Google ScholarBack to article
  97. <bold>Mobeen F, Sharma V, Tulika P</bold>. Enterotype Variations of the Healthy Human Gut Microbiome in Different Geographical Regions. Bioinformation. 2018 Dec; 14:560–573. <a href="https://doi.org/10.6026/97320630014560" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.6026/97320630014560</a>
    Search in Google ScholarBack to article
  98. <bold>Morgan RL, Preidis GA, Kashyap PC, et al</bold>. Probiotics reduce mortality and morbidity in preterm, low-birth-weight infants: a systematic review and network meta-analysis of randomized trials. Gastroenterology. 2020 Aug;159(2):467–480.e19. <a href="https://doi.org/10.1053/J.GASTRO.2020.05.096" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1053/J.GASTRO.2020.05.096</a>
    Search in Google ScholarBack to article
  99. <bold>Mudaliar SB, Poojary SS, Bharath Prasad AS, Mazumder N</bold>. Probiotics and paraprobiotics: effects on microbiota–gut–brain axis and their consequent potential in neuropsychiatric therapy. Probiotics Antimicrob Proteins. 2024 Aug; 16:1440–1464. <a href="https://doi.org/10.1007/s12602-024-10214-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s12602-024-10214-6</a>
    Search in Google ScholarBack to article
  100. <bold>Munawar N, Ahsan K, Muhammad K, et al</bold>. Hidden role of gut microbiome dysbiosis in schizophrenia: antipsychotics or psychobiotics as therapeutics? Int J Mol Sci. 2021 Jul; 22:7671. <a href="https://doi.org/10.3390/ijms22147671" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/ijms22147671</a>
    Search in Google ScholarBack to article
  101. <bold>Naghibi M, Pont-Beltran A, Lamelas A, et al</bold>. Effect of Postbiotic Bifidobacterium longum CECT 7347 on Gastrointestinal Symptoms, Serum Biochemistry, and Intestinal Microbiota in Healthy Adults: A Randomised, Parallel, Double-Blind, Placebo-Controlled Pilot Study. Nutrients. 2024 Nov; 16:3952. <a href="https://doi.org/10.3390/nu16223952" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/nu16223952</a>
    Search in Google ScholarBack to article
  102. <bold>Niu HL, Xiao JY</bold>. The efficacy and safety of probiotics in patients with irritable bowel syndrome: Evidence based on 35 randomized controlled trials. Int J Surg. 2020 Mar; 75:116–127. <a href="https://doi.org/10.1016/J.IJSU.2020.01.142" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.IJSU.2020.01.142</a>
    Search in Google ScholarBack to article
  103. <bold>O’Riordan KJ, Collins MK, Moloney GM, et al</bold>. Short chain fatty acids: microbial metabolites for gut-brain axis signalling. Mol Cell Endocrinol. 2022 Sep; 546:111572. <a href="https://doi.org/10.1016/j.mce.2022.111572" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.mce.2022.111572</a>
    Search in Google ScholarBack to article
  104. <bold>O’Toole PW, Marchesi JR, Hill C</bold>. Next-generation probiotics: the spectrum from probiotics to live biotherapeutics. Nat Microbiol. 2017 May; 2:17057. <a href="https://doi.org/10.1038/nmicrobiol.2017.57" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/nmicrobiol.2017.57</a>
    Search in Google ScholarBack to article
  105. Okburan G, Kızıler S. Human milk oligosaccharides as prebiotics. Pediatr Neonatol. 2023 Apr; 64:231–238. <a href="https://doi.org/10.1016/j.pedneo.2022.09.017" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.pedneo.2022.09.017</a>
    Search in Google ScholarBack to article
  106. <bold>Osbelt L, Wende M, Almási É, et al</bold>. Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition. Cell Host Microbe. 2021 Dec; 29:1663–1679. <a href="https://doi.org/10.1016/j.chom.2021.09.003" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.chom.2021.09.003</a>
    Search in Google ScholarBack to article
  107. <bold>Ottman N, Reunanen J, Meijerink M, et al</bold>. Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function. PLoS One. 2017 Mar; 12(3):e0173004. <a href="https://doi.org/10.1371/journal.pone.0173004" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1371/journal.pone.0173004</a>
    Search in Google ScholarBack to article
  108. <bold>Ouwehand AC, Invernici MM, Furlaneto FAC, Messora MR</bold>. Effectiveness of multistrain versus single-strain probiotics: current status and recommendations for the future. J Clin Gastroenterol. 2018 Nov/Dec;52(Suppl 1):S35–S40. <a href="https://doi.org/10.1097/MCG.0000000000001052" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1097/MCG.0000000000001052</a>
    Search in Google ScholarBack to article
  109. <bold>Piewngam P, Khongthong S, Roekngam N, et al</bold>. Probiotic for pathogen-specific Staphylococcus aureus decolonisation in Thailand: a phase 2, double-blind, randomised, placebo-controlled trial. Lancet Microbe. 2023 Feb; 4:e75–e85. <a href="https://doi.org/10.1016/S2666-5247(22)00322-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/S2666-5247(22)00322-6</a>
    Search in Google ScholarBack to article
  110. <bold>Poaty Ditengou JIC, Ahn SI, Chae B, Choi NJ</bold>. Are heat-killed probiotics more effective than live ones on colon length shortness, disease activity index, and the histological score of an inflammatory bowel disease-induced murine model? A meta-analysis. J Appl Microbiol. 2023 Dec; 134:lxad008. <a href="https://doi.org/10.1093/jambio/lxad008" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1093/jambio/lxad008</a>
    Search in Google ScholarBack to article
  111. <bold>Prygiel M, Mosiej E, Górska P, Zasada AA</bold>. Diphtheria–tetanus–pertussis vaccine: past, current &amp; future. Future Microbiol. 2022 Mar; 17:185–197. <a href="https://doi.org/10.2217/fmb-2021-0167" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.2217/fmb-2021-0167</a>
    Search in Google ScholarBack to article
  112. <bold>Puccetti M, Xiroudaki S, Ricci M, Giovagnoli S</bold>. Postbiotic-enabled targeting of the host–microbiota–pathogen interface: hints of antibiotic decline? Pharmaceutics. 2020 Jul; 12:624. <a href="https://doi.org/10.3390/pharmaceutics12070624" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/pharmaceutics12070624</a>
    Search in Google ScholarBack to article
  113. <bold>Rafique N, Yousuf Jan S, Hussain Dar A, et al</bold>. Promising bioactivities of postbiotics: a comprehensive review. J Agric Food Res. 2023 May; 14:100708. <a href="https://doi.org/10.1016/j.jafr.2023.100708" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.jafr.2023.100708</a>
    Search in Google ScholarBack to article
  114. <bold>Rahman A, Alqaisi S, Nath J</bold>. Internal Medicine, Memorial Hospital Pembroke, Pembroke Pines, USA 3. Imaging Cardiology, Memorial Hospital Pembroke. Cureus. 2023 Dec; 15:e38049. <a href="https://doi.org/10.7759/cureus.38049" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.7759/cureus.38049</a>
    Search in Google ScholarBack to article
  115. <bold>Rios Garza D, Gonze D, Zafeiropoulos H, et al</bold>. Metabolic models of human gut microbiota: Advances and challenges. Cell Syst. 2023 Jan; 14:109–121. <a href="https://doi.org/10.1016/J.CELS.2022.11.002" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.CELS.2022.11.002</a>
    Search in Google ScholarBack to article
  116. <bold>Roth W, Zadeh K, Vekariya R, et al</bold>. Tryptophan Metabolism and Gut-Brain Homeostasis. Int J Mol Sci. 2021 Mar; 22:2973. <a href="https://doi.org/10.3390/ijms22062973" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/ijms22062973</a>
    Search in Google ScholarBack to article
  117. <bold>Ruszkowski J, Szewczyk A, Witkowski JM</bold>. Przegląd doustnych pre-biotyków, probiotyków, synbiotyków i postbiotyków dostępnych na polskim rynku aptecznym. Farm Pol. 2018 Mar; 74:114–122. <a href="https://doi.org/10.32383/farmpol/119464" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.32383/farmpol/119464</a>
    Search in Google ScholarBack to article
  118. <bold>Saad M, Ibrahim W, Hasanin AH, et al</bold>. Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway. RSC Med Chem. 2024 Oct; 15:3817. <a href="https://doi.org/10.1039/D4MD00477A" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1039/D4MD00477A</a>
    Search in Google ScholarBack to article
  119. <bold>Salminen S, Collado MC, Endo A, et al</bold>. The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nat Rev Gastroenterol Hepatol. 2021 Sep; 18:649–667. <a href="https://doi.org/10.1038/s41575-021-00440-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/s41575-021-00440-6</a>
    Search in Google ScholarBack to article
  120. <bold>Salva S, Tiscornia I, Gutiérrez F, et al</bold>. Lactobacillus rhamnosus postbiotic-induced immunomodulation as safer alternative to the use of live bacteria. Cytokine. 2021 Aug; 146:155631. <a href="https://doi.org/10.1016/j.cyto.2021.155631" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.cyto.2021.155631</a>
    Search in Google ScholarBack to article
  121. <bold>Sarkar A, Harty S, Johnson KVA, et al</bold>. The role of the microbiome in the neurobiology of social behaviour. Biol Rev Camb Philos Soc. 2020 Aug; 95:1131–1166. <a href="https://doi.org/10.1111/BRV.12603" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/BRV.12603</a>
    Search in Google ScholarBack to article
  122. <bold>Sarkar A, Lehto SM, Harty S, et al</bold>. Psychobiotics and the manipulation of bacteria–gut–brain signals. Trends Neurosci. 2016 Nov; 39:763–781. <a href="https://doi.org/10.1016/J.TINS.2016.09.002" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.TINS.2016.09.002</a>
    Search in Google ScholarBack to article
  123. <bold>Segers A, de Vos WM</bold>. Mode of action of Akkermansia muciniphila in the intestinal dialogue: role of extracellular proteins, metabolites and cell envelope components. Microbiome Res Rep. 2023 Jun; 2:6. <a href="https://doi.org/10.20517/MRR.2023.05" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.20517/MRR.2023.05</a>
    Search in Google ScholarBack to article
  124. <bold>Sharma R, Gupta D, Mehrotra R, Mago P</bold>. Psychobiotics: the next-generation probiotics for the brain. Curr Microbiol. 2021 Feb; 78:449–463. <a href="https://doi.org/10.1007/s00284-020-02289-5" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s00284-020-02289-5</a>
    Search in Google ScholarBack to article
  125. <bold>Shukla VV, Shah RC</bold>. Vaccinations in primary care. Indian J Pediatr. 2018 Dec; 85:1118–1127. <a href="https://doi.org/10.1007/s12098-017-2555-2" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s12098-017-2555-2</a>
    Search in Google ScholarBack to article
  126. <bold>Shuoker B, Pichler MJ, Jin C, et al</bold>. Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria. Nat Commun. 2023 Apr;14:2182. <a href="https://doi.org/10.1038/S41467-023-37533-6" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41467-023-37533-6</a>
    Search in Google ScholarBack to article
  127. <bold>Singh TP, Natraj BH</bold>. Next-generation probiotics: a promising approach towards designing personalized medicine. Crit Rev Microbiol. 2021 Jul; 47:479–498. <a href="https://doi.org/10.1080/1040841x.2021.1902940" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/1040841x.2021.1902940</a>
    Search in Google ScholarBack to article
  128. <bold>Sionek B, Kołożyn-Krajewska D</bold>. Bezpieczeństwo stosowania probiotyków przez ludzi. Żywność Nauka Technologia Jakość. 2019; 26:5–21. <a href="https://doi.org/10.15193/ZNTJ/2019/120/293" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.15193/ZNTJ/2019/120/293</a>
    Search in Google ScholarBack to article
  129. <bold>Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, et al</bold>. The Effectiveness of Synbiotic Preparation Containing Lactobacillus and Bifidobacterium Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome—A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020 Jul; 12:1999. <a href="https://doi.org/10.3390/NU12071999" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU12071999</a>
    Search in Google ScholarBack to article
  130. <bold>Socała K, Doboszewska U, Szopa A, et al</bold>. The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders. Pharmacol Res. 2021 Jul; 172:105840. <a href="https://doi.org/10.1016/j.phrs.2021.105840" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.phrs.2021.105840</a>
    Search in Google ScholarBack to article
  131. <bold>Song EJ, Han K, Lim TJ, et al</bold>. Effect of probiotics on obesity-related markers per enterotype: a double-blind, placebo-controlled, randomized clinical trial. EPMA J. 2020 Mar; 11:31–44. <a href="https://doi.org/10.1007/S13167-020-00198-Y" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/S13167-020-00198-Y</a>
    Search in Google ScholarBack to article
  132. <bold>Spacova I, O’Neill C, Lebeer S</bold>. Lacticaseibacillus rhamnosus GG inhibits infection of human keratinocytes by Staphylococcus aureus through mechanisms involving cell surface molecules and pH reduction. Benef Microbes. 2020 Nov; 11(8):703-716. <a href="https://doi.org/10.3920/BM2020.0075" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3920/BM2020.0075</a>
    Search in Google ScholarBack to article
  133. <bold>Srivastava S, Basak U, Naghibi M, et al</bold>. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024 Jan-Dec; 16:. <a href="https://doi.org/10.1080/19490976.2024.2338322" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2024.2338322</a>
    Search in Google ScholarBack to article
  134. <bold>Stage M, Wichmann A, Jørgensen M, et al</bold>. Lactobacillus rhamnosus GG genomic and phenotypic stability in an industrial production process. Appl Environ Microbiol. 2020 Apr; 86:e02780-19. <a href="https://doi.org/10.1128/AEM.02780-19/SUPPL_FILE/AEM.02780-19-S0001.PDF" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1128/AEM.02780-19/SUPPL_FILE/AEM.02780-19-S0001.PDF</a>
    Search in Google ScholarBack to article
  135. <bold>Sun Z, Zhao Z, Fang B, et al</bold>. Effect of thermal inactivation on antioxidant, anti-inflammatory activities and chemical profile of postbiotics. Foods. 2023 Oct; 12:3579. <a href="https://doi.org/10.3390/foods12193579" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/foods12193579</a>
    Search in Google ScholarBack to article
  136. <bold>Swanson KS, Gibson GR, Hutkins R, et al</bold>. The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics. Nat Rev Gastroenterol Hepatol. 2020 Oct; 17:687–701. <a href="https://doi.org/10.1038/S41575-020-0344-2" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/S41575-020-0344-2</a>
    Search in Google ScholarBack to article
  137. <bold>Tanihiro R, Yuki M, Sasai M, et al</bold>. Effects of Prebiotic Yeast Mannan on Gut Health and Sleep Quality in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients. 2024 Jan; 16:141. <a href="https://doi.org/10.3390/NU16010141/S1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/NU16010141/S1</a>
    Search in Google ScholarBack to article
  138. <bold>Tian P, Chen Y, Zhu H, et al</bold>. Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: a randomized clinical trial. Brain Behav Immun. 2022 Mar; 100:233–241. <a href="https://doi.org/10.1016/J.BBI.2021.11.023" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.BBI.2021.11.023</a>
    Search in Google ScholarBack to article
  139. <bold>Vallet N, Salmona M, Malet-Villemagne J, et al</bold>. Circulating T cell profiles associate with enterotype signatures underlying hematological malignancy relapses. Cell Host Microbe. 2023 Aug; 31:1386– 1403.e6. <a href="https://doi.org/10.1016/J.CHOM.2023.06.009" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.CHOM.2023.06.009</a>
    Search in Google ScholarBack to article
  140. <bold>Vega-Sagardía M, Delgado J, Ruiz-Moyano S, Garrido D</bold>. Proteomic analyses of Bacteroides ovatus and Bifidobacterium longum in xylan bidirectional culture shows sugar cross-feeding interactions. Food Res Int. 2023 Jun; 170:113025. <a href="https://doi.org/10.1016/J.FOODRES.2023.113025" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.FOODRES.2023.113025</a>
    Search in Google ScholarBack to article
  141. <bold>Vergin F</bold>. Antiund Probiotika. Hippokrates. 1954; 25:116–119
    Search in Google ScholarBack to article
  142. <bold>Vinderola G, Sanders ME, Cunningham M, Hill C</bold>. Frequently asked questions about the ISAPP postbiotic definition. Front Microbiol. 2024 Jan; 14:1324565. <a href="https://doi.org/10.3389/fmicb.2023.1324565" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fmicb.2023.1324565</a>
    Search in Google ScholarBack to article
  143. <bold>Vinderola G, Sanders ME, Salminen S</bold>. The concept of postbiotics. Foods. 2022 Apr; 11:1077. <a href="https://doi.org/10.3390/foods11081077" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/foods11081077</a>
    Search in Google ScholarBack to article
  144. <bold>Walter J, Maldonado-Gómez MX, Martínez I</bold>. To engraft or not to engraft: an ecological framework for gut microbiome modulation with live microbes. Curr Opin Biotechnol. 2018 Dec; 49:129–139. <a href="https://doi.org/10.1016/J.COPBIO.2017.08.008" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.COPBIO.2017.08.008</a>
    Search in Google ScholarBack to article
  145. <bold>Wang Y, Li N, Yang JJ, et al</bold>. Probiotics and fructo-oligosaccharide intervention modulate the microbiota–gut brain axis to improve autism spectrum, reducing also the hyper-serotonergic state and the dopamine metabolism disorder. Pharmacol Res. 2020 May; 157:104784. <a href="https://doi.org/10.1016/j.phrs.2020.104784" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.phrs.2020.104784</a>
    Search in Google ScholarBack to article
  146. <bold>Warda AK, Rea K, Fitzgerald P, et al</bold>. Heat-killed lactobacilli alter both microbiota composition and behaviour. Behav Brain Res. 2019 Mar; 362:213–223. <a href="https://doi.org/10.1016/J.BBR.2018.12.047" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/J.BBR.2018.12.047</a>
    Search in Google ScholarBack to article
  147. <bold>Wu J, Xin Y, Kong J, Guo T</bold>. Genetic tools for the development of recombinant lactic acid bacteria. Microb Cell Fact. 2021 Jul; 20:168. <a href="https://doi.org/10.1186/S12934-021-01607-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S12934-021-01607-1</a>
    Search in Google ScholarBack to article
  148. <bold>Yang J, Hou L, Wang A, et al</bold>. Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled trial. J Clin Invest. 2024 Feb; 134:e176507. <a href="https://doi.org/10.1172/JCI176507" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1172/JCI176507</a>
    Search in Google ScholarBack to article
  149. <bold>Yoon SA, Lim Y, Byeon HR, et al</bold>. Heat-killed Akkermansia muciniphila ameliorates allergic airway inflammation in mice. Front Microbiol. 2024 Jul; 15:1386428. <a href="https://doi.org/10.3389/fmicb.2024.1386428" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fmicb.2024.1386428</a>
    Search in Google ScholarBack to article
  150. <bold>Yuan H, Zhou J, Li N, et al</bold>. Isolation and identification of mucin-degrading bacteria originated from human faeces and their potential probiotic efficacy according to host-microbiome enterotype. J Appl Microbiol. 2022 Jul; 133:362–374. <a href="https://doi.org/10.1111/JAM.15560" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/JAM.15560</a>
    Search in Google ScholarBack to article
  151. <bold>Zhang Y, Tan P, Zhao Y, Ma X</bold>. Enterotoxigenic Escherichia coli: intestinal pathogenesis mechanisms and colonization resistance by gut microbiota. Gut Microbes. 2022 Apr; 14:2055943. <a href="https://doi.org/10.1080/19490976.2022.2055943" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/19490976.2022.2055943</a>
    Search in Google ScholarBack to article
  152. <bold>Zheng J, Wittouck S, Salvetti E, et al</bold>. A taxonomic note on the genus Lactobacillus: description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae. Int J Syst Evol Microbiol. 2020 Jul; 70:2782–2858. <a href="https://doi.org/10.1099/IJSEM.0.004107/CITE/REFWORKS" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1099/IJSEM.0.004107/CITE/REFWORKS</a>
    Search in Google ScholarBack to article
  153. <bold>Zheng QX, Jiang XM, Wang HW, et al</bold>. Probiotic supplements alleviate gestational diabetes mellitus by restoring the diversity of gut microbiota: a study based on 16S rRNA sequencing. J Microbiol. 2021 Jul; 59:827–839. <a href="https://doi.org/10.1007/S12275-021-1094-8" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/S12275-021-1094-8</a>
    Search in Google ScholarBack to article
  154. <bold>Zhong Y, Wang T, Luo R, et al</bold>. Recent advances and potentiality of postbiotics in the food industry: composition, inactivation methods, current applications in metabolic syndrome, and future trends. Crit Rev Food Sci Nutr. 2024 Jun; 64:5768–5792. <a href="https://doi.org/10.1080/10408398.2022.2158174" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/10408398.2022.2158174</a>
    Search in Google ScholarBack to article
  155. <bold>Zhong Y, Wang T, Luo R, et al</bold>. Recent advances and potentiality of postbiotics in the food industry: composition, inactivation methods, current applications in metabolic syndrome, and future trends. Crit Rev Food Sci Nutr. 2022 Nov; 64:5768–5792. <a href="https://doi.org/10.1080/10408398.2022.2158174" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/10408398.2022.2158174</a>
    Search in Google ScholarBack to article
  156. <bold>Zhou Z, Chen X, Sheng H, et al</bold>. Engineering probiotics as living diagnostics and therapeutics for improving human health. Microb Cell Fact. 2020 May; 19:111. <a href="https://doi.org/10.1186/S12934-020-01318-Z" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/S12934-020-01318-Z</a>
    Search in Google ScholarBack to article
  157. <bold>Zhu R, Fang Y, Li H, et al</bold>. Psychobiotic Lactobacillus plantarum JYLP-326 relieves anxiety, depression, and insomnia symptoms in test-anxious college students via modulating the gut microbiota and its metabolism. Front Immunol. 2023 Apr; 14:1158137. <a href="https://doi.org/10.3389/FIMMU.2023.1158137/FULL" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/FIMMU.2023.1158137/FULL</a>
    Search in Google ScholarBack to article
  158. <bold>Zhu Y, Xiao M, Kang T, et al</bold>. The role of inactivation methods in shaping postbiotic composition and modulating bioactivity: a review. Foods. 2025 Jul; 14:2358. <a href="https://doi.org/10.3390/foods14132358" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/foods14132358</a>
    Search in Google ScholarBack to article
  159. <bold>Zikou E, Dovrolis N, Dimosthenopoulos C, et al</bold>. The effect of probiotic supplements on metabolic parameters of people with type 2 diabetes in Greece—A randomized, double-blind, placebo-controlled study. Nutrients. 2023 Nov; 15:4663. <a href="https://doi.org/10.3390/nu15214663" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/nu15214663</a>
    Search in Google ScholarBack to article
DOI: https://doi.org/10.2478/am-2025-0013 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
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Language: English, Polish
Page range: 160 - 181
Submitted on: Apr 29, 2025
Accepted on: Sep 25, 2025
Published on: Sep 30, 2025
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
probiotics,
prebiotics,
synbiotics,
postbiotics,
next-generation probiotics,
live biotherapeutic products
Related subjects:
Life sciences,
Microbiology and virology

© 2025 Antoni Woźniak, Agata Dorotkiewicz-Jach, Monika Brzychczy-Włoch, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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