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Akkermansia Muciniphila is Associated with Human Health: What Should we Know? Cover

Akkermansia Muciniphila is Associated with Human Health: What Should we Know?

Advancements of Microbiology
Volume 64 (2025): Issue 3 (September 2025)
By:
Open Access
|Sep 2025

Figures & Tables

Figure1.

Summary of the role of A.muciniphila in health and disease. Illustration created using Biorender (www.biorender.com). Agreement number: CA28PV7H2E
Summary of the role of A.muciniphila in health and disease. Illustration created using Biorender (www.biorender.com). Agreement number: CA28PV7H2E

Akkermansia muciniphila is positively associated with improved metabolic profiles, enhanced mucosal immunity, and a robust epithelial barrier_

MechanismEffectReference
Mucin degradation + mucus stimulationPromotes goblet cell proliferation and maintains mucus thicknessSi et al. (2022)
Barrier reinforcementEnhances tight junctions (ZO1, occludin, claudins), and TER ↑
Immune modulation↓ proinflammatory cytokines, ↑ IL-10, and ↑ Tregs
DOI: https://doi.org/10.2478/am-2025-0011 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
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Language: English, Polish
Page range: 141 - 146
Submitted on: Apr 29, 2025
Accepted on: Jul 23, 2025
Published on: Sep 30, 2025
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
disease,
microbiota,
probiotics
Related subjects:
Life sciences,
Microbiology and virology

© 2025 Bartosz Ostrowski, Beata Krawczyk, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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