Fig. 1.

Fig. 2.

Top 10 institutes by number of publications on sepsis and gut microbiome_
| Institutions | Publications | Percentage (%)* |
|---|---|---|
| University of California | 88 | 3.54 |
| University of Amsterdam | 85 | 3.42 |
| Udice French Research Universities | 63 | 2.54 |
| University of Chicago | 60 | 2.41 |
| Institute National De La Sante | 50 | 2.01 |
| University of Michigan | 45 | 1.81 |
| Harvard University | 39 | 1.57 |
| Newcastle University UK | 35 | 1.41 |
| Southern Medical University China | 34 | 1.37 |
| University of Minnesota | 30 | 1.21 |
Top 10 authors by number of publications on sepsis and gut microbiome_
| Ranks | Authors | Publications | Percentage (%)* |
|---|---|---|---|
| 1 | Wiersinga WJ | 44 | 1.77 |
| 2 | Alverdy John C | 17 | 0.68 |
| 3 | Berrington JE | 14 | 0.56 |
| 4 | Leelahavanichkul A | 15 | 0.60 |
| 5 | Embleton ND | 12 | 0.48 |
| 6 | van der Poll T | 11 | 0.44 |
| 7 | Stewart CJ | 10 | 0.40 |
| 8 | Dickson RP | 7 | 0.28 |
| 9 | Wang W | 6 | 0.24 |
| 10 | Haak BW | 6 | 0.2 |
Distribution of keywords_
| Keywords | Frequency | Percentage (%)* |
|---|---|---|
| Sepsis | 2174 | 87.48 |
| Microbiome | 991 | 39.88 |
| Microbiota | 765 | 30.78 |
| Flora | 382 | 15.37 |
| Antibiotics | 337 | 13.56 |
| Gut microbiota | 306 | 12.31 |
| Immune system | 218 | 8.77 |
| Bacteria | 184 | 7.40 |
| Gut | 163 | 6.56 |
| Gastrointestinal microbiome | 152 | 6.12 |
Type of publications on sepsis and gut microbiome_
| Type | Publications | Percentage (%)* |
|---|---|---|
| Original articles | 1671 | 67.24 |
| Reviews | 279 | 11.23 |
| Clinical trial | 105 | 4.23 |
| Meeting | 228 | 9.18 |
| Editorials | 72 | 2.90 |
| Abstract | 63 | 2.54 |
| Online first | 27 | 1.09 |
| Case Report | 40 | 1.61 |
Research directions of publications on sepsis and gut microbiome_
| Directions | Publications | Percentage (%)* |
|---|---|---|
| Infectious diseases | 1657 | 66.68 |
| Gastroenterology hepatology | 1428 | 57.46 |
| Biochemistry molecular biology | 1074 | 43.22 |
| Immunology | 1039 | 41.81 |
| Pathology | 956 | 38.49 |
| Microbiology | 931 | 37.46 |
| Nutrition dietetics | 914 | 36.78 |
| Pharmacology pharmacy | 879 | 35.37 |
| Food Science technology | 708 | 28.49 |
| Genetics heredity | 703 | 28.29 |
Centrality of countries in the studies on sepsis and gut microbiome_
| Ranks | Countries | Centrality |
|---|---|---|
| 1 | USA | 0.36 |
| 2 | France | 0.24 |
| 3 | Germany | 0.21 |
| 4 | England | 0.20 |
| 5 | Italy | 0.17 |
| 6 | Netherlands | 0.16 |
| 7 | Spain | 0.15 |
| 8 | Australia | 0.13 |
| 9 | Canada | 0.12 |
| 10 | China | 0.11 |
Top 10 authors by centrality on sepsis and gut microbiom_
| Ranks | Authors | Centrality |
|---|---|---|
| 1 | Wiersinga WJ | 0.26 |
| 2 | Alverdy John C | 0.23 |
| 3 | Leelahavanichkul A | 0.19 |
| 4 | Embleton ND | 0.18 |
| 5 | Wang YJ | 0.17 |
| 6 | Cao ZJ | 0.17 |
| 7 | Wang W | 0.17 |
| 8 | He ZY | 0.15 |
| 9 | Liu S | 0.14 |
| 10 | Li SL | 0.13 |
Top 10 journals by publication of literatures on sepsis and microbiome
| Journals | Publications | Percentage (%)* | 2022 IF |
|---|---|---|---|
| Figshare | 166 | 6.67 | Database |
| Nutrients | 90 | 3.64 | 6.706 |
| Critical Care | 81 | 3.24 | 19.334 |
| Plos One | 78 | 3.13 | 3.752 |
| Scientific Reports | 73 | 2.93 | 4.996 |
| European Nucleotide Archive | 68 | 2.73 | Database |
| Frontiers in Microbiology | 60 | 2.42 | 6.064 |
| Frontiers in Immunology | 50 | 2.02 | 8.786 |
| Pediatric Research | 45 | 1.82 | 3.953 |
| International Journal of Molecular Sciences | 40 | 1.62 | 6.208 |
Top 10 institutes by centrality on sepsis and gut microbiome_
| Ranks | Institutions | Centrality |
|---|---|---|
| 1 | University of California | 0.24 |
| 2 | University of Amsterdam | 0.23 |
| 3 | University of Chicago | 0.18 |
| 4 | Udice French Research Universities | 0.17 |
| 5 | Institut National De La Sante | 0.15 |
| 6 | University of Michigan | 0.14 |
| 7 | University of Florida | 0.13 |
| 8 | Chulalongkorn University | 0.12 |
| 9 | Northumbria University | 0.11 |
| 10 | Universidade De Sao Paulo | 0.11 |