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Infections Connected with Organ and Tissue Transplantation Cover

Infections Connected with Organ and Tissue Transplantation

Open Access
|Jul 2024

Figures & Tables

Organ transplants in different geographical regions in 2022 (ONT-WHO Global Observatory on Donation and Transplantation)_

Organ transplantation in 2022Geographical region
PolandEuropeanAmericasEastern MediterraneanWestern PacificSouth-East AsiaAfricanGlobal
Kidney87425,36139,1966,36418,21912,696286102,122
Liver3629,84013,3871,8178,3254,067(−)37,436
Heart1732,4444,9961841,090274(−)8,988
Lung932,0733,313551,199144(−)6,784
Pancreas186111,1715615830(−)2,026
Small bowel(−)409014233(−)170
Total organ transplants1,52040,36962,1538,49029,01417,214286157,526

Composition of preservation solutions (Jing et al_ 2018; Guibert et al_ 2011; Finger et al_ 2023; Petrenko et al_ 2019; Latchana et al_ 2015; Datta et al_ 2021)_

SolutionElectrolytes (nmol/L)BufferAntioxidantColloid/ImpermeantAmino acidsOtherpHOsmolality (mOsm/L)Intracellular/Extrracellular
EC (Euro-Collins)K+ (115), Na+ (10), Mg2+ (5), Cl (15)Phosphate (50; 57.5; 60), Bicarbonate (10)Glucose (19.5; 180; 195)7.3; 7.4340; 355; 375I
UW (University of Wisconsin, Viaspan)K+ (125), Na+ (25), Mg2+ (5), Cl (20)Phosphate (25)Glutatione (3), Allopurinol (1)Pentafraction – HES (50 g/L), Lactobionate (100), Raffinose (30)Sulphate (5), Adenosine (5) Insulin (40 U/L), Dexamethasone 16 mg/L), Penicillin G 200,000 UI/L)7.40 (25°C)320; 324I
CelsiorK+ (15), Na+ (100), Mg2+ (13), Ca2+ (0.25), Cl (28; 41.5; 71)Histidine HCl (30)Glutatione (3), Mannitol (60)Lactobionate (80), MannitolHistidine, Glutamate (20)Sucrose7.30 (20°C)242; 360; 368E
HTK (Custodiol)K+ (9; 10), Na+ (15), Mg2+ (4), Ca2+ (0.015), Cl (32; 50)Histidine (180) Histidine HCl (18)Tryptophan (2), Mannitol (30), α-Ketoglutarate (1)MannitolHistidine, Tryptophan, Glutamate 7.02–7.20 (25°C)310E
HTK-New (Custodiol-N)K+ (10), Na+ (16), Mg2+ (8), Ca2+ (0.02), Cl (30)Histidine (124), N-acetyl-L-histidine (57)Tryptophan, α-Ketoglutarate (2)Histidine, Glicyne (10) Tryptophan (2), Alanine (5), Arginine (3), Aspartate (5)Sucrose (33), Deferoxamine (25 × 10−3), LK-614 (7.5 × 10−3)7.0–7.1302E
IGL-1 (Institut Georges Lopez-1)K+ (25; 30), Na+ (120; 125), Mg2+ (5), Ca2+ (0.03–0.5), Cl (0; 20)Phosphate (25)Glutatione (3), Allopurinol (1)Lactobionate (100), Raffinose (30), PEG-35 (0.03; 1)Nitroglycerin, Adenosine (5) Sulphate (5)7.40 (25°C)290; 320E
LPDG (Perfadex)K+ (6), Na+ (138), Mg2+ (0.8), Ca2+ (0.3), Cl (142)Phosphate (0.8), Tris or Bicarbonate (1)Dextran 40 (50)Glucose (5) Sulphate (0.8)7.4295E
Ep4 (EP-TU)K+ (26), Na+ (141), Mg2+ (4), Cl (103)PhosphateDextran 40Glucose (10)E
ET-Kyoto (ETK)K+ (44), Na+ (100)Phosphate (25)Pentafraction – HES (30), Trehalose (41; 120)Sulphate, Gluconate (100), Dibutyryl cAMP7.4370E
HOC – hypertonic citrateK+ (79), Na+ (84), Cl (30)CitrateMannitol (185)I
PBS – phosphate buffered sucroseNa+ (120)Phosphate (60)Sucrose (140)7.40310I
ScotK+ (5), Na+ (118), Mg2+ (1.2), Ca2+ (1.75), Cl (128.9)PEG-20 (30)Glucose (11)7.50302E
HTK-TiProtecK+ (93), Na+ (16), Mg2+ (6; 8), Ca2+ (0.05), Cl (103)Phosphate (1) or Histidine (198) N-acetyl-L-histidine (30)α-Ketoglutarate (2)Glicyne (5; 10) Tryptophan (2), Alanine (5), Aspartate (5; 8)Glucose (10), Sucrose (20; 37), Deferoxamine (82 × 10–3), LK-614 (17 × 10–3)7.0305I
KH (Krebs-Henseleit)K+ (5.9), Na+ (143), Mg2+ (1.2), Ca2+ (1.25), Cl (125.2)Phosphate (1.2) Bicarbonate (25)Sulphate (1.2), Glucose (11)7.8380E
DOI: https://doi.org/10.2478/am-2024-0006 | Journal eISSN: 2545-3149 | Journal ISSN: 0079-4252
Language: English, Polish
Page range: 65 - 80
Submitted on: May 1, 2024
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Accepted on: Jun 1, 2024
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Published on: Jul 3, 2024
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Agnieszka E. Laudy, Stefan Tyski, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.